Cryo-EM structure of NRG1A(LRR) in complex with EDS1-SAG101-(ADPr-ATP)
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8yn1
Q-score: 0.561
Huang S, Wang J, Song R, Jia A, Xiao Y, Sun Y, Wang L, Mahr D, Wu Z, Han Z, Li X, Parker JE, Chai J
Nature (2025) [ Pubmed: 39939760 DOI: doi:10.1038/s41586-024-08521-7 ]
- Senescence-associated carboxylesterase 101 (61 kDa, Protein from Arabidopsis thaliana)
- Probable disease resistance protein at5g66900 (46 kDa, Protein from Arabidopsis thaliana)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ternary complex of nrg1a(lrr) with eds1-sag101-(adpr-atp) (Complex from Arabidopsis)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Protein eds1 (70 kDa, Protein from Arabidopsis thaliana)
The Cryo-EM structure of DSR2-Tail tube-NAD+ complex
Wang R, Xu Q, Wu Z, Li J, Guo H, Liao T, Shi Y, Yuan L, Gao H, Yang R, Shi Z, Li F
Nat Commun (2024) 15 pp. 6185-6185 [ DOI: doi:10.1038/s41467-024-50410-0 Pubmed: 39039073 ]
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
- Tail tube protein (29 kDa, Protein from Bacillus subtilis)
- Dsr2-tail tube protein-nad+ complex (Complex from Bacillus subtilis)
- Sir2-like domain-containing protein (118 kDa, Protein from Bacillus subtilis)
Cryo-EM structure of the ISFba1 TnpB-reRNA-dsDNA complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8iaz
Q-score: 0.548
Ren K, Zhou F, Zhang F, Yin M, Zhu Y, Wang S, Chen Y, Huang T, Wu Z, He J, Zhang A, Guo C, Huang Z
Cell Res (2024) 34 pp. 370-385 [ DOI: doi:10.1038/s41422-024-00952-1 Pubmed: 38575718 ]
- The complex of protein with grna and target dna (Complex from Firmicutes bacterium AM43-11BH)
- Dna (5'-d(p*cp*cp*ap*tp*tp*ap*gp*gp*ap*gp*cp*tp*gp*ap*tp*g)-3') (4 kDa, DNA from Firmicutes bacterium AM43-11BH)
- Transposase (44 kDa, Protein from Firmicutes bacterium AM43-11BH)
- Dna (5'-d(p*ap*cp*ap*tp*gp*gp*ap*cp*cp*ap*tp*cp*ap*gp*cp*tp*cp*cp*tp*ap*ap*tp*gp*g)-3') (7 kDa, DNA from Firmicutes bacterium AM43-11BH)
- Zinc ion (65 Da, Ligand)
- Rna (207-mer) (66 kDa, RNA from Firmicutes bacterium AM43-11BH)
OEA bound GPR3-Gs complex structure
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8x2k
Q-score: 0.532
Chen G, Staffen N, Wu Z, Xu X, Pan J, Inoue A, Shi T, Gmeiner P, Du Y, Xu J
Cell Res (2024) 34 pp. 262-265 [ Pubmed: 38287118 DOI: doi:10.1038/s41422-023-00919-8 ]
- Gpr3, guanine nucleotide-binding protein g(s) subunit alpha, guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1,guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Gpr3-gs-scfv16 complex (150 kDa, Complex from Homo sapiens)
- Scfv16 (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,g-protein coupled receptor 3 (50 kDa, Protein from Homo sapiens)
- Isoform gnas-2 of guanine nucleotide-binding protein g(s) subunit alpha isoforms short (43 kDa, Protein from Homo sapiens)
- Gpr3 (Complex from Homo sapiens)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- (z)-n-(2-hydroxyethyl)octadec-9-enamide (325 Da, Ligand)
CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with astemizole
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8x5y
Q-score: 0.463
Wang D, Guo Q, Wu Z, Li M, He B, Du Y, Zhang K, Tao Y
Nat Commun (2024) 15 pp. 84-84 [ DOI: doi:10.1038/s41467-023-44477-4 Pubmed: 38167898 ]
- Histamine h1 receptor,soluble cytochrome b562 (50 kDa, Protein from Homo sapiens)
- Cryoem structure of the histamine h1 receptor-bril/anti bril fab complex with astemizole (Complex from Homo sapiens)
- 1-[(4-fluorophenyl)methyl]-n-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1h-benzimidazol-2-amine (458 Da, Ligand)
CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with mepyramine
CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with desloratadine
Cryo-EM structure of human HCAR2-Gi complex with niacin
Resolution: 2.69 Å
EM Method: Single-particle
Fitted PDBs: 8ija
Q-score: 0.574
Pan X, Ye F, Ning P, Zhang Z, Li X, Zhang B, Wang Q, Chen G, Gao W, Qiu C, Wu Z, Li J, Zhu L, Xia J, Gong K, Du Y
Cell Discov (2023) 9 pp. 118-118 [ DOI: doi:10.1038/s41421-023-00610-7 Pubmed: 38012147 ]
- Cryo-em structure of human hcar2-gi complex with niacin (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Hydroxycarboxylic acid receptor 2 (34 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Nicotinic acid (123 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
Multi-drug efflux pump RE-CmeB bound with Erythromycin
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 8gk0
Q-score: 0.441
Zhang Z, Lizer N, Wu Z, Morgan CE, Yan Y, Zhang Q, Yu EW
Microbiol Spectr (2023) 11 pp. e0119723-e0119723 [ DOI: doi:10.1128/spectrum.01197-23 Pubmed: 37289051 ]
- Efflux pump membrane transporter (114 kDa, Protein from Campylobacter jejuni)
- Erythromycin a (733 Da, Ligand)
- Re-cmeb (Complex from Campylobacter jejuni)
