Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 7wrh
Q-score: 0.468
Li L, Han P, Huang B, Xie Y, Li W, Zhang D, Han P, Xu Z, Bai B, Zhou J, Kang X, Li X, Zheng A, Zhang R, Qiao S, Zhao X, Qi J, Wang Q, Liu K, Gao GF
Cell Discov (2022) 8 pp. 65-65 [ Pubmed: 35821014 DOI: doi:10.1038/s41421-022-00431-0 ]
- Sars-cov-2 omicron ba.1 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 omicron ba.1 spike protein with mouse ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (138 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Mouse ace2 (Complex)
- Processed angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with S309 fab
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7xco
Q-score: 0.433
Zhao Z, Zhou J, Tian M, Huang M, Liu S, Xie Y, Han P, Bai C, Han P, Zheng A, Fu L, Gao Y, Peng Q, Li Y, Chai Y, Zhang Z, Zhao X, Song H, Qi J, Wang Q, Wang P, Gao GF
Nat Commun (2022) 13 pp. 4958- [ DOI: doi:10.1038/s41467-022-32665-7 ]
- Cryo-em structure of sars-cov-2 omicron spike protein in complex with s309 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- S309 fab (Complex)
- Sars-cov-2 omicron spike protein (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S309 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (138 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 7y9z
Q-score: 0.365
Zhao Z, Zhou J, Tian M, Huang M, Liu S, Xie Y, Han P, Bai C, Han P, Zheng A, Fu L, Gao Y, Peng Q, Li Y, Chai Y, Zhang Z, Zhao X, Song H, Qi J, Wang Q, Wang P, Gao GF
Nat Commun (2022) 13 pp. 4958-4958 [ DOI: doi:10.1038/s41467-022-32665-7 Pubmed: 36002453 ]
- Processed angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Processed angiotensin-converting enzyme 2 (Complex)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (Complex from Homo sapiens)
- Cryo-em structure of sars-cov-2 omicron spike protein in complex with human ace2 ectodomain (one-rbd-up state) (Complex from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of SARS-CoV-2 Omicron RBD in complex with S309 fab (local refinement)
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7xck
Q-score: 0.548
Zhao Z, Zhou J, Tian M, Huang M, Liu S, Xie Y, Han P, Bai C, Han P, Zheng A, Fu L, Gao Y, Peng Q, Li Y, Chai Y, Zhang Z, Zhao X, Song H, Qi J, Wang Q, Wang P, Gao GF
Nat Commun (2022) 13 pp. 4958- [ DOI: doi:10.1038/s41467-022-32665-7 ]
- Spike protein s1 (30 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 omicron rbd in complex with s309 fab (local refinement) (Complex from Homo sapiens)
- Sars-cov-2 omicron rbd (Complex)
- S309 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- S309 heavy chain (24 kDa, Protein from Homo sapiens)
- S309 light chain (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of S309-RBD-RBD-S309 in the S309-bound Omicron spike protein (local refinement)
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 7yad
Q-score: 0.439
Zhao Z, Zhou J, Tian M, Huang M, Liu S, Xie Y, Han P, Bai C, Han P, Zheng A, Fu L, Gao Y, Peng Q, Li Y, Chai Y, Zhang Z, Zhao X, Song H, Qi J, Wang Q, Wang P, Gao GF
Nat Commun (2022) 13 pp. 4958-4958 [ DOI: doi:10.1038/s41467-022-32665-7 Pubmed: 36002453 ]
- Cryo-em structure of the omicron rbd-rbd-s309 complex from the s309-bound omicron spike protein (local refinement) (Complex from Homo sapiens)
- S309 neutralizing antibody light chain (11 kDa, Protein from Homo sapiens)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S309 antibody fab (Complex)
- Sars-cov-2 omicron rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- S309 neutralizing antibody heavy chain (13 kDa, Protein from Homo sapiens)
The complex structure of Omicron BA.1 RBD with BD604, S309,and S304
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 7x1m
Q-score: 0.552
Huang M, Wu L, Zheng A, Xie Y, He Q, Rong X, Han P, Du P, Han P, Zhang Z, Zhao R, Jia Y, Li L, Bai B, Hu Z, Hu S, Niu S, Hu Y, Liu H, Liu B, Cui K, Li W, Zhao X, Liu K, Qi J, Wang Q, Gao GF
Immunity (2022) 55 pp. 1501-1514.e3 [ Pubmed: 35777362 DOI: doi:10.1016/j.immuni.2022.06.005 ]
- Bd-604 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Omicron ba.1 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Bd-604 fab light chain (23 kDa, Protein from Homo sapiens)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- S309 fab heavy chain (24 kDa, Protein from Homo sapiens)
- S304 fab haavy chain (23 kDa, Protein from Homo sapiens)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
- Bd604 fab, s309 fab and s304 fab complex with omicron ba.1 rbd (Complex)
- Bd604 fab, s309 fab and s304 fab (Complex from Homo sapiens)