Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8xqw
Q-score: 0.502
Liang K, Zhan X, Li Y, Yang Y, Xie Y, Jin Z, Xu X, Zhang W, Lu Y, Zhang S, Zou Y, Feng S, Wu J, Yan Z
Cell (2024) 187 pp. 5638-5650.e18 [ Pubmed: 39197449 DOI: doi:10.1016/j.cell.2024.08.002 ]
- Arhl (51 kDa, Protein from Chlamydomonas reinhardtii)
- Tic22 (40 kDa, Protein from Chlamydomonas reinhardtii)
- Diacyl glycerol (625 Da, Ligand)
- Unk (13 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam35 (34 kDa, Protein from Chlamydomonas reinhardtii)
- The ycf2-ftshi motor complex from chlamydomonas (Complex from Chlamydomonas reinhardtii)
- Zinc ion (65 Da, Ligand)
- Dnaj (50 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap6 (109 kDa, Protein from Chlamydomonas reinhardtii)
- 1,2-di-o-acyl-3-o-[6-deoxy-6-sulfo-alpha-d-glucopyranosyl]-sn-glycerol (795 Da, Ligand)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Acp (12 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam34 (34 kDa, Protein from Chlamydomonas reinhardtii)
- Pcya (61 kDa, Protein from Chlamydomonas reinhardtii)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Crtam31 (31 kDa, Protein from Chlamydomonas reinhardtii)
- Fhl3 (120 kDa, Protein from Chlamydomonas reinhardtii)
- Beta-sitosterol (416 Da, Ligand)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Crtam49 (48 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap7 (71 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap1 (107 kDa, Protein from Chlamydomonas reinhardtii)
- Unk (7 kDa, Protein from Chlamydomonas reinhardtii)
- Magnesium ion (24 Da, Ligand)
- Fhl1 (128 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam29 (29 kDa, Protein from Chlamydomonas reinhardtii)
- Fadl (70 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam15 (15 kDa, Protein from Chlamydomonas reinhardtii)
- Ycf2 (342 kDa, Protein from Chlamydomonas reinhardtii)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Crtam39 (39 kDa, Protein from Chlamydomonas reinhardtii)
Cryo-EM structure of the Ycf2-FtsHi motor complex from chlamydomonas reinhardtii in apo state
Liang K, Zhan X, Li Y, Yang Y, Xie Y, Jin Z, Xu X, Zhang W, Lu Y, Zhang S, Zou Y, Feng S, Wu J, Yan Z
Cell (2024) 187 pp. 5638-5650.e18 [ Pubmed: 39197449 DOI: doi:10.1016/j.cell.2024.08.002 ]
- Arhl (51 kDa, Protein from Chlamydomonas reinhardtii)
- Tic22 (40 kDa, Protein from Chlamydomonas reinhardtii)
- Diacyl glycerol (625 Da, Ligand)
- Unk (13 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam35 (34 kDa, Protein from Chlamydomonas reinhardtii)
- The ycf2-ftshi motor complex from chlamydomonas (Complex from Chlamydomonas reinhardtii)
- Zinc ion (65 Da, Ligand)
- Dnaj (50 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap6 (109 kDa, Protein from Chlamydomonas reinhardtii)
- 1,2-di-o-acyl-3-o-[6-deoxy-6-sulfo-alpha-d-glucopyranosyl]-sn-glycerol (795 Da, Ligand)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Acp (12 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam34 (34 kDa, Protein from Chlamydomonas reinhardtii)
- Pcya (61 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam31 (31 kDa, Protein from Chlamydomonas reinhardtii)
- Fhl3 (120 kDa, Protein from Chlamydomonas reinhardtii)
- Beta-sitosterol (416 Da, Ligand)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Crtam49 (48 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap7 (71 kDa, Protein from Chlamydomonas reinhardtii)
- Ctap1 (107 kDa, Protein from Chlamydomonas reinhardtii)
- Unk (7 kDa, Protein from Chlamydomonas reinhardtii)
- Magnesium ion (24 Da, Ligand)
- Fhl1 (128 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam29 (29 kDa, Protein from Chlamydomonas reinhardtii)
- Fadl (70 kDa, Protein from Chlamydomonas reinhardtii)
- Crtam15 (15 kDa, Protein from Chlamydomonas reinhardtii)
- Ycf2 (342 kDa, Protein from Chlamydomonas reinhardtii)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Crtam39 (39 kDa, Protein from Chlamydomonas reinhardtii)
Omicron BA.4/5 SARS-CoV-2 S in complex with TH027 Fab
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yve
Q-score: 0.47
Guo Y, Zhang G, Yang Q, Xie X, Lu Y, Cheng X, Wang H, Liang J, Tang J, Gao Y, Shang H, Dai J, Shi Y, Zhou J, Zhou J, Guo H, Yang H, Qi J, Liu L, Ma S, Zhang B, Huo Q, Xie Y, Wu J, Dong F, Zhang S, Lou Z, Gao Y, Song Z, Wang W, Sun Z, Yang X, Xiong D, Liu F, Chen X, Zhu P, Wang X, Cheng T, Rao Z
Nat Commun (2023) 14 pp. 3537-3537 [ Pubmed: 37322000 DOI: doi:10.1038/s41467-023-39267-x ]
- Th027 fab (Complex from Homo sapiens)
- Th027 fab light chain (11 kDa, Protein from Homo sapiens)
- Omicron ba.4/5 sars-cov-2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Omicron ba.5 sars-cov-2 s in complex with th027 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Th027 fab heavy chain (13 kDa, Protein from Homo sapiens)
Omicron BA.4/5 SARS-CoV-2 S in complex with TH132 Fab
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yvg
Q-score: 0.384
Guo Y, Zhang G, Yang Q, Xie X, Lu Y, Cheng X, Wang H, Liang J, Tang J, Gao Y, Shang H, Dai J, Shi Y, Zhou J, Zhou J, Guo H, Yang H, Qi J, Liu L, Ma S, Zhang B, Huo Q, Xie Y, Wu J, Dong F, Zhang S, Lou Z, Gao Y, Song Z, Wang W, Sun Z, Yang X, Xiong D, Liu F, Chen X, Zhu P, Wang X, Cheng T, Rao Z
Nat Commun (2023) 14 pp. 3537-3537 [ Pubmed: 37322000 DOI: doi:10.1038/s41467-023-39267-x ]
- Th132 fab light chain (11 kDa, Protein from Homo sapiens)
- Th027 fab (Complex from Homo sapiens)
- Th132 fab heavy chain (12 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Omicron ba.4/5 sars-cov-2 s (Complex from Severe acute respiratory syndrome coronavirus 2)
- Omicron ba.4/5 sars-cov-2 s in complex with th027 fab (Complex)
Omicron BA.4/5 SARS-CoV-2 S in complex with TH236 Fab
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7yvi
Q-score: 0.414
Guo Y, Zhang G, Yang Q, Xie X, Lu Y, Cheng X, Wang H, Liang J, Tang J, Gao Y, Shang H, Dai J, Shi Y, Zhou J, Zhou J, Guo H, Yang H, Qi J, Liu L, Ma S, Zhang B, Huo Q, Xie Y, Wu J, Dong F, Zhang S, Lou Z, Gao Y, Song Z, Wang W, Sun Z, Yang X, Xiong D, Liu F, Chen X, Zhu P, Wang X, Cheng T, Rao Z
Nat Commun (2023) 14 pp. 3537-3537 [ Pubmed: 37322000 DOI: doi:10.1038/s41467-023-39267-x ]
- Th236 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Th027 fab (Complex from Homo sapiens)
- Th236 fab light chain (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Omicron ba.4/5 sars-cov-2 s (Complex from Severe acute respiratory syndrome coronavirus 2)
- Omicron ba.4/5 sars-cov-2 s in complex with th027 fab (Complex)
Omicron BA.4/5 SARS-CoV-2 S in complex with TH272 Fab
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yvk
Q-score: 0.428
Guo Y, Zhang G, Yang Q, Xie X, Lu Y, Cheng X, Wang H, Liang J, Tang J, Gao Y, Shang H, Dai J, Shi Y, Zhou J, Zhou J, Guo H, Yang H, Qi J, Liu L, Ma S, Zhang B, Huo Q, Xie Y, Wu J, Dong F, Zhang S, Lou Z, Gao Y, Song Z, Wang W, Sun Z, Yang X, Xiong D, Liu F, Chen X, Zhu P, Wang X, Cheng T, Rao Z
Nat Commun (2023) 14 pp. 3537-3537 [ Pubmed: 37322000 DOI: doi:10.1038/s41467-023-39267-x ]
- Th272 fab light chain (11 kDa, Protein from Homo sapiens)
- Th027 fab (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Th272 fab heavy chain (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Omicron ba.4/5 sars-cov-2 s (Complex from Severe acute respiratory syndrome coronavirus 2)
- Omicron ba.4/5 sars-cov-2 s in complex with th027 fab (Complex)
Omicron BA.4/5 SARS-CoV-2 S in complex with TH281 Fab
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yvn
Q-score: 0.368
Guo Y, Zhang G, Yang Q, Xie X, Lu Y, Cheng X, Wang H, Liang J, Tang J, Gao Y, Shang H, Dai J, Shi Y, Zhou J, Zhou J, Guo H, Yang H, Qi J, Liu L, Ma S, Zhang B, Huo Q, Xie Y, Wu J, Dong F, Zhang S, Lou Z, Gao Y, Song Z, Wang W, Sun Z, Yang X, Xiong D, Liu F, Chen X, Zhu P, Wang X, Cheng T, Rao Z
Nat Commun (2023) 14 pp. 3537-3537 [ Pubmed: 37322000 DOI: doi:10.1038/s41467-023-39267-x ]
- Th281 fab heavy chain (12 kDa, Protein from Homo sapiens)
- Th281 fab light chain (11 kDa, Protein from Homo sapiens)
- Th281 fab (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Omicron ba.4/5 sars-cov-2 s in complex with th281 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Omicron ba.4/5 sars-cov-2 s (Complex from Severe acute respiratory syndrome coronavirus 2)
Omicron BA.4/5 SARS-CoV-2 S in complex with TH027/132 Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7yvo
Q-score: 0.349
Guo Y, Zhang G, Yang Q, Xie X, Lu Y, Cheng X, Wang H, Liang J, Tang J, Gao Y, Shang H, Dai J, Shi Y, Zhou J, Zhou J, Guo H, Yang H, Qi J, Liu L, Ma S, Zhang B, Huo Q, Xie Y, Wu J, Dong F, Zhang S, Lou Z, Gao Y, Song Z, Wang W, Sun Z, Yang X, Xiong D, Liu F, Chen X, Zhu P, Wang X, Cheng T, Rao Z
Nat Commun (2023) 14 pp. 3537-3537 [ Pubmed: 37322000 DOI: doi:10.1038/s41467-023-39267-x ]
- Th132 fab light chain (11 kDa, Protein from Homo sapiens)
- Th27 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Th132 fab heavy chain (12 kDa, Protein from Homo sapiens)
- Th27 fab light chain (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Omicron ba.4/5 sars-cov-2 s (Complex from Severe acute respiratory syndrome coronavirus 2)
- Omicron ba.4/5 sars-cov-2 s in complex with th027 fab (Complex)
- H132, h027 fab (Complex from Homo sapiens)
Omicron BA.4/5 SARS-CoV-2 S in complex with TH272/281 Fab
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7yvp
Q-score: 0.325
Guo Y, Zhang G, Yang Q, Xie X, Lu Y, Cheng X, Wang H, Liang J, Tang J, Gao Y, Shang H, Dai J, Shi Y, Zhou J, Zhou J, Guo H, Yang H, Qi J, Liu L, Ma S, Zhang B, Huo Q, Xie Y, Wu J, Dong F, Zhang S, Lou Z, Gao Y, Song Z, Wang W, Sun Z, Yang X, Xiong D, Liu F, Chen X, Zhu P, Wang X, Cheng T, Rao Z
Nat Commun (2023) 14 pp. 3537-3537 [ Pubmed: 37322000 DOI: doi:10.1038/s41467-023-39267-x ]
- Th272 fab light chain (11 kDa, Protein from Homo sapiens)
- Th281 fab heavy chain (12 kDa, Protein from Homo sapiens)
- Omicron ba.4/5 sars-cov-2 s in complex with th272/281 fab (Complex)
- Th281 fab light chain (11 kDa, Protein from Homo sapiens)
- Th272/281 fab (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Th272 fab heavy chain (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Omicron ba.4/5 sars-cov-2 s (Complex from Severe acute respiratory syndrome coronavirus 2)
Omicron BA.4/5 SARS-CoV-2 S in complex with TH003 Fab
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8gou
Q-score: 0.362
Guo Y, Zhang G, Yang Q, Xie X, Lu Y, Cheng X, Wang H, Liang J, Tang J, Gao Y, Shang H, Dai J, Shi Y, Zhou J, Zhou J, Guo H, Yang H, Qi J, Liu L, Ma S, Zhang B, Huo Q, Xie Y, Wu J, Dong F, Zhang S, Lou Z, Gao Y, Song Z, Wang W, Sun Z, Yang X, Xiong D, Liu F, Chen X, Zhu P, Wang X, Cheng T, Rao Z
Nat Commun (2023) 14 pp. 3537-3537 [ Pubmed: 37322000 DOI: doi:10.1038/s41467-023-39267-x ]
- Omicron ba.4/5 sars-cov-2 s in complex with th003 fab (Complex)
- Th003 fab light chain (11 kDa, Protein from Homo sapiens)
- Th003 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Omicron ba.4/5 sars-cov-2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Th003 fab (Complex from Homo sapiens)