Structure of STING SAVI-related mutant V147L
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 8gsz
Q-score: 0.445
human STING With agonist HB3089
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8gt6
Q-score: 0.443
Xie Z, Wang Z, Fan F, Zhou J, Hu Z, Wang Q, Wang X, Zeng Q, Zhang Y, Qiu J, Zhou X, Xu H, Bai H, Zhan Z, Ding J, Zhang H, Duan W, Yu X, Geng M
Cell Discov (2022) 8 pp. 133-133 [ Pubmed: 36513640 DOI: doi:10.1038/s41421-022-00481-4 ]
- Stimulator of interferon genes protein (42 kDa, Protein from Homo sapiens)
- Human sting with agonist hb3089 (Complex from Homo sapiens)
- 1-[(2e)-4-{5-carbamoyl-2-[(1-ethyl-3-methyl-1h-pyrazole-5-carbonyl)amino]-7-[3-(morpholin-4-yl)propoxy]-1h-benzimidazol-1-yl}but-2-en-1-yl]-2-[(1-ethyl-3-methyl-1h-pyrazole-5-carbonyl)amino]-7-methyl-1h-furo[3,2-e]benzimidazole-5-carboxamide (873 Da, Ligand)
Complex of Echo 18 and FcRn at pH7.4
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 7xxa
Q-score: 0.49
Chen X, Qu X, Liu C, Zhang Y, Zhang G, Han P, Duan Y, Li Q, Wang L, Ruan W, Wang P, Wei W, Gao GF, Zhao X, Xie Z
Mbio (2022) 13 pp. e0116622-e0116622 [ DOI: doi:10.1128/mbio.01166-22 Pubmed: 35862785 ]
- Vp2 (28 kDa, Protein from Echovirus E18)
- Echovirus e18 (Complex from Echovirus E18)
- Igg receptor fcrn large subunit p51 (29 kDa, Protein from Homo sapiens)
- Homo sapiens (Virus from Homo sapiens)
- Fcrn (Complex)
- Vp3 (26 kDa, Protein from Echovirus E18)
- Vp4 (7 kDa, Protein from Echovirus E18)
- Vp1 (35 kDa, Protein from Echovirus E18)
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 7xxg
Q-score: 0.358
Chen X, Qu X, Liu C, Zhang Y, Zhang G, Han P, Duan Y, Li Q, Wang L, Ruan W, Wang P, Wei W, Gao GF, Zhao X, Xie Z
Mbio (2022) 13 pp. e0116622-e0116622 [ Pubmed: 35862785 DOI: doi:10.1128/mbio.01166-22 ]
- Vp1 (31 kDa, Protein from Echovirus E18)
- Echovirus e18 (Virus from Echovirus E18)
- Vp2 (28 kDa, Protein from Echovirus E18)
- Vp4 (7 kDa, Protein from Echovirus E18)
- Palmitic acid (256 Da, Ligand)
- Vp3 (26 kDa, Protein from Echovirus E18)
Echo 18 incubated with FcRn at pH5.5
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 7xxj
Q-score: 0.491
Chen X, Qu X, Liu C, Zhang Y, Zhang G, Han P, Duan Y, Li Q, Wang L, Ruan W, Wang P, Wei W, Gao GF, Zhao X, Xie Z
Mbio (2022) 13 pp. e0116622-e0116622 [ Pubmed: 35862785 DOI: doi:10.1128/mbio.01166-22 ]
- Echovirus e18 (Virus from Echovirus E18)
- Vp2 (28 kDa, Protein from Echovirus E18)
- Vp4 (7 kDa, Protein from Echovirus E18)
- Palmitic acid (256 Da, Ligand)
- Vp3 (26 kDa, Protein from Echovirus E18)
- Vp1 (31 kDa, Protein from Echovirus E18)
Cryo-EM structure of human TRPV3 determined in lipid nanodisc
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6uw4
Q-score: 0.529
Deng Z, Maksaev G, Rau M, Xie Z, Hu H, Fitzpatrick JAJ, Yuan P
Nat Struct Mol Biol (2020) 27 pp. 635-644 [ DOI: doi:10.1038/s41594-020-0428-2 Pubmed: 32572252 ]
- Human trpv3 (Complex from Homo sapiens)
- Transient receptor potential cation channel subfamily v member 3 (90 kDa, Protein from Homo sapiens)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Sodium ion (22 Da, Ligand)
Cryo-EM structure of the human TRPV3 K169A mutant determined in lipid nanodisc
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 6uw6
Q-score: 0.485
Deng Z, Maksaev G, Rau M, Xie Z, Hu H, Fitzpatrick JAJ, Yuan P
Nat Struct Mol Biol (2020) 27 pp. 635-644 [ DOI: doi:10.1038/s41594-020-0428-2 Pubmed: 32572252 ]
Resolution: 4.02 Å
EM Method: Single-particle
Fitted PDBs: 6uw8
Q-score: 0.434
Deng Z, Maksaev G, Rau M, Xie Z, Hu H, Fitzpatrick JAJ, Yuan P
Nat Struct Mol Biol (2020) 27 pp. 635-644 [ Pubmed: 32572252 DOI: doi:10.1038/s41594-020-0428-2 ]
Resolution: 4.33 Å
EM Method: Single-particle
Fitted PDBs: 6uw9
Q-score: 0.383
Deng Z, Maksaev G, Rau M, Xie Z, Hu H, Fitzpatrick JAJ, Yuan P
Nat Struct Mol Biol (2020) 27 pp. 635-644 [ Pubmed: 32572252 DOI: doi:10.1038/s41594-020-0428-2 ]
Cryo-EM structure of Echovirus 6 complexed with its attachment receptor CD55 at PH 5.5
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6ilj
Q-score: 0.51
Zhao X, Zhang G, Liu S, Chen X, Peng R, Dai L, Qu X, Li S, Song H, Gao Z, Yuan P, Liu Z, Li C, Shang Z, Li Y, Zhang M, Qi J, Wang H, Du N, Wu Y, Bi Y, Gao S, Shi Y, Yan J, Zhang Y, Xie Z, Wei W, Gao GF
Cell (2019) 177 pp. 1553-1565.e16 [ Pubmed: 31104841 DOI: doi:10.1016/j.cell.2019.04.035 ]
- Complement decay-accelerating factor (21 kDa, Protein from Homo sapiens)
- Capsid protein vp3 (26 kDa, Protein from Echovirus E6)
- Capsid protein vp2 (28 kDa, Protein from Echovirus E6)
- Sphingosine (299 Da, Ligand)
- Capsid protein vp1 (31 kDa, Protein from Echovirus E6)
- Capsid protein vp4 (7 kDa, Protein from Echovirus E6)
- Cryo-em structure of echovirus 6 complexed with its attachment receptor cd55 at ph 5.5 (Complex from Echovirus E6)