Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8iv4
Q-score: 0.506
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
- Heavy chain of 8h12 (13 kDa, Protein from Mus musculus)
- Light chain of 8h12 (11 kDa, Protein from Mus musculus)
- Cryo-em structure of sars-cov-2 spike protein in complex with double nabs 3e2 and 1c4 (Complex)
- Heavy chain of 3e2 (13 kDa, Protein from Mus musculus)
- Light chain of 3e2 (11 kDa, Protein from Mus musculus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Nabs 8h12 and 3e2 (Complex from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.77 Å
EM Method: Single-particle
Fitted PDBs: 8iv5
Q-score: 0.494
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
- Heavy chain of 1c4 (13 kDa, Protein from Mus musculus)
- Heavy chain of 8h12 (13 kDa, Protein from Mus musculus)
- Light chain of 8h12 (11 kDa, Protein from Mus musculus)
- Nabs 8h12,1c4 (Complex from Mus musculus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 spike protein in complex with 8h12 (Complex)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 1c4 (11 kDa, Protein from Mus musculus)
Resolution: 3.92 Å
EM Method: Single-particle
Fitted PDBs: 8iv8
Q-score: 0.444
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
- Heavy chain of 1c4 (13 kDa, Protein from Mus musculus)
- Cryo-em structure of sars-cov-2 spike protein in complex with double nabs 3e2 and 1c4 (Complex)
- Heavy chain of 3e2 (13 kDa, Protein from Mus musculus)
- Light chain of 3e2 (11 kDa, Protein from Mus musculus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Nabs 3e2 and 1c4 (Complex from Mus musculus)
- Light chain of 1c4 (11 kDa, Protein from Mus musculus)
Resolution: 3.95 Å
EM Method: Single-particle
Fitted PDBs: 8iva
Q-score: 0.46
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
- Heavy chain of xma01 (13 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 spike protein in complex with double nabs 3e2 and 1c4 (Complex)
- Light chain of xma01 (11 kDa, Protein from Homo sapiens)
- Heavy chain of 3e2 (13 kDa, Protein from Mus musculus)
- Light chain of 3e2 (11 kDa, Protein from Mus musculus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Nab 3e2 (Complex from Mus musculus)
- Nab xma01 (Complex from Homo sapiens)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8fdt
Q-score: 0.426
Ton WD, Wang Y, Chai P, Beauchamp-Perez C, Flint NT, Lammers LG, Xiong H, Zhang K, Markus SM
Nat Struct Mol Biol (2023) 30 pp. 1365-1379 [ DOI: doi:10.1038/s41594-023-01010-x Pubmed: 37322240 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Engineered human dynein motor domain in microtubule-unbound state with lis1 complex in the buffer containing atp-vi (490 kDa, Complex from Homo sapiens)
- Vanadate ion (114 Da, Ligand)
- Cytoplasmic dynein 1 heavy chain 1,serine--trna ligase (357 kDa, Protein from Homo sapiens)
- Platelet-activating factor acetylhydrolase ib subunit beta (66 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8fdu
Q-score: 0.431
Ton WD, Wang Y, Chai P, Beauchamp-Perez C, Flint NT, Lammers LG, Xiong H, Zhang K, Markus SM
Nat Struct Mol Biol (2023) 30 pp. 1365-1379 [ DOI: doi:10.1038/s41594-023-01010-x Pubmed: 37322240 ]
- Platelet-activating factor acetylhydrolase ib subunit beta,platelet-activating factor acetylhydrolase ib subunit beta,human lis1 protein with a snap tag (66 kDa, Protein from Homo sapiens)
- Engineered human dynein motor domain in microtubule-unbound state with lis1 complex in the buffer containing atp-vi (490 kDa, Complex from Homo sapiens)
- Cytoplasmic dynein 1 heavy chain 1,serine--trna ligase (357 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7wp8
Q-score: 0.441
Wu Y, Wang S, Zhang Y, Yuan L, Zheng Q, Wei M, Shi Y, Wang Z, Ma J, Wang K, Nie M, Xiao J, Huang Z, Chen P, Guo H, Lan M, Xu J, Hou W, Hong Y, Chen D, Sun H, Xiong H, Zhou M, Liu C, Guo W, Guo H, Gao J, Gan C, Li Z, Zhang H, Wang X, Li S, Cheng T, Zhao Q, Chen Y, Wu T, Zhang T, Zhang J, Cao H, Zhu H, Yuan Q, Guan Y, Xia N
Cell Host Microbe (2022) 30 pp. 1732-1744.e7 [ Pubmed: 36323313 DOI: doi:10.1016/j.chom.2022.10.011 ]
- 85f7 light chain (11 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 85f7 heavy chain (13 kDa, Protein from Mus musculus)
- Neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 recombinant spike protein stfk1628x in complex with three neutralizing antibodies (Complex from Mus musculus)
- Spike protein stfk1628x (Complex)
- 83h7 light chain (11 kDa, Protein from Mus musculus)
- 2b4 light chain (12 kDa, Protein from Mus musculus)
- 83h7 heavy chain (13 kDa, Protein from Mus musculus)
- Spike glycoprotein (20 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2b4 heavy chain (13 kDa, Protein from Mus musculus)
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 7wp6
Q-score: 0.438
Wu Y, Wang S, Zhang Y, Yuan L, Zheng Q, Wei M, Shi Y, Wang Z, Ma J, Wang K, Nie M, Xiao J, Huang Z, Chen P, Guo H, Lan M, Xu J, Hou W, Hong Y, Chen D, Sun H, Xiong H, Zhou M, Liu C, Guo W, Guo H, Gao J, Gan C, Li Z, Zhang H, Wang X, Li S, Cheng T, Zhao Q, Chen Y, Wu T, Zhang T, Zhang J, Cao H, Zhu H, Yuan Q, Guan Y, Xia N
Cell Host Microbe (2022) 30 pp. 1732-1744.e7 [ Pubmed: 36323313 DOI: doi:10.1016/j.chom.2022.10.011 ]
- 85f7 light chain (11 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 85f7 heavy chain (13 kDa, Protein from Mus musculus)
- Neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein stfk (Complex)
- 83h7 light chain (11 kDa, Protein from Mus musculus)
- 83h7 heavy chain (13 kDa, Protein from Mus musculus)
- 36h6 light chain (12 kDa, Protein from Mus musculus)
- 36h6 heavy chain (13 kDa, Protein from Mus musculus)
- Cryo-em structure of sars-cov-2 recombinant spike protein stfk in complex with three neutralizing antibodies (Complex from Mus musculus)
Cryo-EM structure of SARS-CoV-2 spike protein in complex with three nAbs X01, X10 and X17
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 7x7t
Q-score: 0.504
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N
PNAS (2022) 119 pp. e2204256119-e2204256119 [ DOI: doi:10.1073/pnas.2204256119 Pubmed: 35972965 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 spike protein in complex with three nabs x01, x10 and x17 (Complex)
- X01 heavy chain (13 kDa, Protein from Mus musculus)
- Nabs x01, x10 and x17 (Complex from Mus musculus)
- X17 light chain (11 kDa, Protein from Mus musculus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- X17 heavy chain (13 kDa, Protein from Mus musculus)
- X01 light chain (11 kDa, Protein from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- X10 light chain (12 kDa, Protein from Mus musculus)
- X10 heavy chain (13 kDa, Protein from Mus musculus)
Resolution: 3.77 Å
EM Method: Single-particle
Fitted PDBs: 7x7u
Q-score: 0.49
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N
PNAS (2022) 119 pp. e2204256119-e2204256119 [ DOI: doi:10.1073/pnas.2204256119 Pubmed: 35972965 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- X01 heavy chain (13 kDa, Protein from Mus musculus)
- Nabs x01, x10 and x17 (Complex from Mus musculus)
- X10 light chain (12 kDa, Protein from Mus musculus)
- X17 light chain (11 kDa, Protein from Mus musculus)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- X17 heavy chain (13 kDa, Protein from Mus musculus)
- X01 light chain (11 kDa, Protein from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 delta variant spike protein in complex with three nabs x01, x10 and x17 (Complex)
- X10 heavy chain (13 kDa, Protein from Mus musculus)