Cryo-EM structure of human dimeric Apelin receptor.
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8xqi
Q-score: 0.454
Yue Y, Liu L, Wu L, Xu C, Na M, Liu S, Liu Y, Li F, Liu J, Shi S, Lei H, Zhao M, Yang T, Ji W, Wang A, Hanson MA, Stevens RC, Liu J, Xu F
Nat Commun (2025) 16 pp. 310-310 [ Pubmed: 39747115 DOI: doi:10.1038/s41467-024-55555-6 ]
- Soluble cytochrome b562,apelin receptor (54 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Homodimer of apelin receptor (Complex from Homo sapiens)
Cryo-EM structure of APJR complex with agonistic antibody
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8z74
Q-score: 0.394
Yue Y, Liu L, Wu L, Xu C, Na M, Liu S, Liu Y, Li F, Liu J, Shi S, Lei H, Zhao M, Yang T, Ji W, Wang A, Hanson MA, Stevens RC, Liu J, Xu F
Nat Commun (2025) 16 pp. 310-310 [ Pubmed: 39747115 DOI: doi:10.1038/s41467-024-55555-6 ]
- Soluble cytochrome b562,apelin receptor (54 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Agonistic antibody (13 kDa, Protein from Homo sapiens)
- Apjr complex with antibody (Complex from Homo sapiens)
Cryo-EM structure of the LSD-bound hTAAR1-Gs complex
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8zsp
Q-score: 0.408
Jiang K, Zheng Y, Zeng L, Wang L, Li F, Pu J, Lu Y, Zhao S, Xu F
Cell Rep (2024) 43 pp. 114505-114505 [ DOI: doi:10.1016/j.celrep.2024.114505 Pubmed: 39002128 ]
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Nb35 (15 kDa, Protein from Lama glama)
- (8alpha)-n,n-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide (323 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,trace amine-associated receptor 1 (56 kDa, Protein from Homo sapiens)
- The lsd-bound htaar1-gs complex (Complex from Homo sapiens)
Cryo-EM structure of the AA-14-bound GPR101-Gs complex
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8w8r
Q-score: 0.558
Yang Z, Wang JY, Yang F, Zhu KK, Wang GP, Guan Y, Ning SL, Lu Y, Li Y, Zhang C, Zheng Y, Zhou SH, Wang XW, Wang MW, Xiao P, Yi F, Zhang C, Zhang PJ, Xu F, Liu BH, Zhang H, Yu X, Gao N, Sun JP
Nat Chem Biol (2024) 20 pp. 484-492 [ DOI: doi:10.1038/s41589-023-01456-6 Pubmed: 37945893 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein g(s) subunit (42 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 101 (56 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- Cryo-em structure of the aa14-bound gpr101-gs complex (Complex from Homo sapiens)
- 1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea (311 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (30 kDa, Protein from Homo sapiens)
Cryo-EM structure of the AA14-bound GPR101 complex
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8w8s
Q-score: 0.471
Cryo-EM structure of the PEA-bound TAAR1-Gs complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8w89
Q-score: 0.507
Liu H, Zheng Y, Wang Y, Wang Y, He X, Xu P, Huang S, Yuan Q, Zhang X, Wang L, Jiang K, Chen H, Li Z, Liu W, Wang S, Xu HE, Xu F
Nature (2023) 624 pp. 663-671 [ Pubmed: 37935377 DOI: doi:10.1038/s41586-023-06775-1 ]
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Trace amine-associated receptor 1 (39 kDa, Protein from Homo sapiens)
- Cryo-em structure of the pea-bound taar1-gs complex (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- 2-phenylethylamine (122 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Nanobody35 (15 kDa, Protein from Lama glama)
Cryo-EM structure of SEP-363856 bounded serotonin 1A (5-HT1A) receptor-Gi protein complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8w8b
Q-score: 0.55
Liu H, Zheng Y, Wang Y, Wang Y, He X, Xu P, Huang S, Yuan Q, Zhang X, Wang L, Jiang K, Chen H, Li Z, Liu W, Wang S, Xu HE, Xu F
Nature (2023) 624 pp. 663-671 [ Pubmed: 37935377 DOI: doi:10.1038/s41586-023-06775-1 ]
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- 1-[(7~{s})-5,7-dihydro-4~{h}-thieno[2,3-c]pyran-7-yl]-~{n}-methyl-methanamine (183 Da, Ligand)
- Cryo-em structure of sep-363856 bounded serotonin 1a (5-ht1a) receptor-gi protein complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,5-hydroxytryptamine receptor 1a (60 kDa, Protein from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- Antibody fragment scfv16 (28 kDa, Protein from Homo sapiens)
cryo-EM structure of human NaV1.3/beta1/beta2-bulleyaconitineA
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7w77
Q-score: 0.449
Li X, Xu F, Xu H, Zhang S, Gao Y, Zhang H, Dong Y, Zheng Y, Yang B, Sun J, Zhang XC, Zhao Y, Jiang D
Nat Commun (2022) 13 pp. 1286-1286 [ DOI: doi:10.1038/s41467-022-28808-5 Pubmed: 35277491 ]
- (3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en (544 Da, Ligand)
- Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
- [(1s,2r,3r,4r,5r,6s,8r,9s,13s,16s,17r,18r)-11-ethyl-5-hydroxy-6,16,18-trimethoxy-4-(4-methoxybenzoyl)-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-8-yl] acetate (627 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sodium channel subunit beta-2 (24 kDa, Protein from Homo sapiens)
- Sodium channel complex of type 3 subunit alpha with auxiliary subunits bata-1 and bata-2 (Complex from Homo sapiens)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Sodium channel protein type 3 subunit alpha (221 kDa, Protein from Homo sapiens)
Cryo-EM structure of human NaV1.3/beta1/beta2-ICA121431
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 7w7f
Q-score: 0.44
Li X, Xu F, Xu H, Zhang S, Gao Y, Zhang H, Dong Y, Zheng Y, Yang B, Sun J, Zhang XC, Zhao Y, Jiang D
Nat Commun (2022) 13 pp. 1286-1286 [ DOI: doi:10.1038/s41467-022-28808-5 Pubmed: 35277491 ]
- (3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en (544 Da, Ligand)
- Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
- Sodium channel complex of type 3 subunit alpha with auxiliary beta-1 and beta-2 (Complex from Homo sapiens)
- 2,2-diphenyl-~{n}-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]ethanamide (449 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sodium channel subunit beta-2 (24 kDa, Protein from Homo sapiens)
- Sodium channel protein type 3 subunit alpha (226 kDa, Protein from Homo sapiens)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
Supercomplex for cylic electron transport in cyanobacteria
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6khi
Q-score: 0.525
Pan X, Cao D, Xie F, Xu F, Su X, Mi H, Zhang X, Li M
Nat Commun (2020) 11 pp. 610-610 [ Pubmed: 32001694 DOI: doi:10.1038/s41467-020-14456-0 ]
- Nadh dehydrogenase subunit 5 (72 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Tlr0472 protein (16 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Ferredoxin-1 (10 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Nad(p)h-quinone oxidoreductase subunit j (19 kDa, Protein from Thermosynechococcus elongatus BP-1)
- 1,2-di-o-acyl-3-o-[6-deoxy-6-sulfo-alpha-d-glucopyranosyl]-sn-glycerol (795 Da, Ligand)
- Nad(p)h-quinone oxidoreductase subunit l (8 kDa, Protein from Thermosynechococcus elongatus BP-1)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Nad(p)h-quinone oxidoreductase subunit m (12 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Nad(p)h-quinone oxidoreductase subunit n (16 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nad(p)h-quinone oxidoreductase subunit i (22 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Nad(p)h-quinone oxidoreductase subunit k (25 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Nad(p)h-quinone oxidoreductase chain 4 1 (57 kDa, Protein from Thermosynechococcus elongatus (strain BP-1))
- Nad(p)h-quinone oxidoreductase subunit 4l (11 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Nad(p)h-quinone oxidoreductase subunit 1 (40 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Proton-translocating nadh-quinone dehydrogenase subunit p (4 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Nad(p)h-quinone oxidoreductase subunit h (45 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Nad(p)h-quinone oxidoreductase subunit o (7 kDa, Protein from Thermosynechococcus elongatus (strain BP-1))
- Nad(p)h-quinone oxidoreductase subunit 2 (55 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Tlr0636 protein (12 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Iron/sulfur cluster (351 Da, Ligand)
- Nad(p)h-quinone oxidoreductase subunit 3 (15 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Nadh-quinone oxidoreductase subunit j (21 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Proton-translocating nadh-quinone dehydrogenase subunit q (4 kDa, Protein from Thermosynechococcus elongatus BP-1)
- Beta-carotene (536 Da, Ligand)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Electron transport complex ndh-fd from cyanobacteria (Complex from Thermosynechococcus elongatus BP-1)