VMAT1 dimer with MPP+ and reserpine
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8tgg
Q-score: 0.371
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Reserpine (608 Da, Ligand)
- Chromaffin granule amine transporter (50 kDa, Protein from Homo sapiens)
- 1-methyl-4-phenylpyridin-1-ium (170 Da, Ligand)
- Complex of vmat1 with mpp+ and reserpine (105 kDa, Complex from Homo sapiens)
VMAT1 dimer with amphetamine and reserpine
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8tgh
Q-score: 0.479
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Chromaffin granule amine transporter (50 kDa, Protein from Homo sapiens)
- Complex of vmat1 with amphetamine and reserpine (105 kDa, Complex from Homo sapiens)
- Reserpine (608 Da, Ligand)
- (2s)-1-phenylpropan-2-amine (135 Da, Ligand)
VMAT1 dimer with dopamine and reserpine
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8tgi
Q-score: 0.396
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- L-dopamine (153 Da, Ligand)
- Reserpine (608 Da, Ligand)
- Chromaffin granule amine transporter (50 kDa, Protein from Homo sapiens)
- Complex of vmat1 dimer with dopamine and reserpine (105 kDa, Complex from Homo sapiens)
VMAT1 dimer in unbound form and with reserpine
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8tgj
Q-score: 0.363
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Reserpine (608 Da, Ligand)
- Vmat1 dimer in unbound form and with reserpine (50 kDa, Protein from Homo sapiens)
- Complex of vmat1 dimer in unbound form and with reserpine (105 kDa, Complex from Homo sapiens)
VMAT1 dimer with histamine and reserpine
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8tgk
Q-score: 0.42
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Complex of vmat1 dimer with histamine and reserpine (105 kDa, Complex from Homo sapiens)
- Chromaffin granule amine transporter (50 kDa, Protein from Homo sapiens)
- Reserpine (608 Da, Ligand)
- Histamine (111 Da, Ligand)
VMAT1 dimer with norepinephrine and reserpine
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8tgl
Q-score: 0.413
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Reserpine (608 Da, Ligand)
- Chromaffin granule amine transporter (50 kDa, Protein from Homo sapiens)
- Complex of vmat1 with norepinephrine and reserpine (105 kDa, Complex from Homo sapiens)
- L-norepinephrine (169 Da, Ligand)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8tgm
Q-score: 0.457
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Reserpine (608 Da, Ligand)
- Vmat1 dimer with reserpine (105 kDa, Complex from Homo sapiens)
- Vmat1 dimer with reserpine (50 kDa, Protein from Homo sapiens)
VMAT1 dimer with serotonin and reserpine
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8tgn
Q-score: 0.365
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Vmat1 dimer with serotonin and reserpine (105 kDa, Complex from Homo sapiens)
- Chromaffin granule amine transporter (50 kDa, Protein from Homo sapiens)
- Reserpine (608 Da, Ligand)
- Serotonin (176 Da, Ligand)