Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9j1w
Q-score: 0.543
cryo-EM structure of Gs-coupled zebrafish GPR4 at pH 6.5
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8zfz
Q-score: 0.41
Ma Y, Wang Y, Tang M, Weng Y, Chen Y, Xu Y, An S, Wu Y, Zhao S, Xu H, Li D, Liu M, Lu W, Ru H, Song G
Nat Commun (2025) 16 pp. 605-605 [ Pubmed: 39799123 DOI: doi:10.1038/s41467-025-55901-2 ]
- Zgpr4-gs complex (Complex from Danio rerio)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,g-protein coupled receptor 4,lgbit (72 kDa, Protein from synthetic construct)
- Scfv16 (30 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
cryo-EM structure of zebrafish GPR4-Gs complex at pH 8.5
Ma Y, Wang Y, Tang M, Weng Y, Chen Y, Xu Y, An S, Wu Y, Zhao S, Xu H, Li D, Liu M, Lu W, Ru H, Song G
Nat Commun (2025) 16 pp. 605-605 [ DOI: doi:10.1038/s41467-025-55901-2 Pubmed: 39799123 ]
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Scfv16 (31 kDa, Protein from Mus musculus)
- Zgpr4-gs complex (Complex from Danio rerio)
- Soluble cytochrome b562,g-protein coupled receptor 4,lgbit (72 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
Structure of LbCas12a-crRNA complex bound to AcrVA4 (form A complex)
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 6kl9
Q-score: 0.434
Peng R, Li Z, Xu Y, He S, Peng Q, Wu LA, Wu Y, Qi J, Wang P, Shi Y, Gao GF
PNAS (2019) 116 pp. 18928-18936 [ Pubmed: 31467167 DOI: doi:10.1073/pnas.1909400116 ]
- Lbcas12a (143 kDa, Protein from Lachnospiraceae bacterium)
- Water (18 Da, Ligand)
- Rna (42-mer) (13 kDa, RNA from synthetic construct)
- Magnesium ion (24 Da, Ligand)
- Lbcas12a-crrna complex bound to acrva4 (form a complex) (170 kDa, Complex from Lachnospiraceae bacterium)
- Acrva4 (27 kDa, Protein from Moraxella bovoculi)
Structure of LbCas12a-crRNA complex bound to AcrVA4 (form B complex)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6klb
Q-score: 0.224
Peng R, Li Z, Xu Y, He S, Peng Q, Wu LA, Wu Y, Qi J, Wang P, Shi Y, Gao GF
PNAS (2019) 116 pp. 18928-18936 [ Pubmed: 31467167 DOI: doi:10.1073/pnas.1909400116 ]
- Lbcas12a (143 kDa, Protein from Lachnospiraceae bacterium)
- Water (18 Da, Ligand)
- Lbcas12a-crrna complex bound to acrva4 (form b complex) (300 kDa, Complex from Lachnospiraceae bacterium)
- Magnesium ion (24 Da, Ligand)
- Acrva4 (27 kDa, Protein from Moraxella bovoculi)
- Crrna (13 kDa, RNA from synthetic construct)