MPOX E5 hexamer 2ATP, 2ADP, and ssDNA binding comformation
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8wh2
Q-score: 0.516
Xu Y, Wu Y, Zhang Y, Gao K, Wu X, Yang Y, Li D, Yang B, Zhang Z, Dong C
Sci Adv (2024) 10 pp. eadl1150-eadl1150 [ DOI: doi:10.1126/sciadv.adl1150 Pubmed: 39167653 ]
- Dna (5'-d(p*cp*cp*cp*cp*c)-3') (1 kDa, DNA from Spodoptera frugiperda)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Mpox helicase (Complex from Monkeypox virus)
- Uncoating factor opg117 (90 kDa, Protein from Monkeypox virus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8xyd
Q-score: 0.366
Fan W, Xu Y, He X, Luo P, Zhu J, Li J, Wang R, Yuan Q, Wu K, Hu W, Zhao Y, Xu S, Cheng X, Wang Y, Xu HE, Zhuang Y
Cell Rep (2024) 43 pp. 114422-114422 [ Pubmed: 38943642 DOI: doi:10.1016/j.celrep.2024.114422 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- (2r)-2-(acetyloxy)-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate (523 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Ptafr-paf g protein complex (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Mus musculus)
- Platelet-activating factor receptor (39 kDa, Protein from Homo sapiens)
Human URAT1 bound to lesinurad
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9jdz
Q-score: 0.361
Wu C, Zhang C, Jin S, Wang JJ, Dai A, Xu J, Zhang H, Yang X, He X, Yuan Q, Hu W, Xu Y, Wang M, Jiang Y, Yang D, Xu HE
bioRxiv (2024) [ DOI: doi:10.1101/2024.09.11.612394 ]
- Lesinurad (404 Da, Ligand)
- Water (18 Da, Ligand)
- Solute carrier family 22 member 12 (59 kDa, Protein from Homo sapiens)
- Human uric acid transportor 1 with lesinurad (Complex from Homo sapiens)
MPOX E5 hexamer ssDNA and AMP-PNP bound conformation
Resolution: 2.51 Å
EM Method: Single-particle
Fitted PDBs: 8wh0
Q-score: 0.589
Xu Y, Wu Y, Zhang Y, Gao K, Wu X, Yang Y, Li D, Yang B, Zhang Z, Dong C
Sci Adv (2024) 10 pp. eadl1150-eadl1150 [ DOI: doi:10.1126/sciadv.adl1150 Pubmed: 39167653 ]
- Dna (5'-d(p*cp*cp*cp*cp*c)-3') (1 kDa, DNA from Spodoptera frugiperda)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Mpox helicase (Complex from Monkeypox virus)
- Uncoating factor opg117 (90 kDa, Protein from Monkeypox virus)
Cryo-electron microscopic structure of an amide hydrolase from Pseudoxanthomonas wuyuanensis
Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 8yag
Q-score: 0.665
Hu Y, Dai L, Xu Y, Niu D, Yang X, Xie Z, Shen P, Li X, Li H, Zhang L, Min J, Guo RT, Chen CC
Int J Biol Macromol (2024) 278 pp. 134831-134831 [ Pubmed: 39163957 DOI: doi:10.1016/j.ijbiomac.2024.134831 ]
- Imidazolonepropionase (43 kDa, Protein from Pseudoxanthomonas wuyuanensis)
- Pwadh (Complex from Pseudoxanthomonas wuyuanensis)
- Zinc ion (65 Da, Ligand)
MPOX E5 hexamer ADP and ssDNA bound and clear primase domain conformation
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 8wh6
Q-score: 0.462
Xu Y, Wu Y, Zhang Y, Gao K, Wu X, Yang Y, Li D, Yang B, Zhang Z, Dong C
Sci Adv (2024) 10 pp. eadl1150-eadl1150 [ DOI: doi:10.1126/sciadv.adl1150 Pubmed: 39167653 ]
- Mpox helicase (Complex from Monkeypox virus)
- Uncoating factor opg117 (90 kDa, Protein from Monkeypox virus)
- Dna (5'-d(p*cp*cp*c)-3') (822 Da, DNA from Spodoptera frugiperda)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Structure of nanobody-bound DRD1_LSD complex
Fan L, Zhuang Y, Wu H, Li H, Xu Y, Wang Y, He L, Wang S, Chen Z, Cheng J, Xu HE, Wang S
Neuron (2024) 112 pp. 3295- [ DOI: doi:10.1016/j.neuron.2024.07.003 Pubmed: 39094559 ]
- Fab 8d3 (Complex from Mus musculus)
- Prac-prad-prg (Complex from Escherichia coli O157:H7)
- (8alpha)-n,n-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide (323 Da, Ligand)
- Drd1 (Complex from Homo sapiens)
- Nanobody-bound drd1_lsd complex (170 kDa, Complex)
- Nba3 (13 kDa, Protein from Homo sapiens)
- Maltose/maltodextrin-binding periplasmic protein,immunoglobulin g-binding protein a,immunoglobulin g-binding protein g (60 kDa, Protein from Streptococcus sp. 'group G')
- Fab 8d3 light chain (26 kDa, Protein from Mus musculus)
- Fab 8d3 heavy chain (27 kDa, Protein from Mus musculus)
- D(1a) dopamine receptor (39 kDa, Protein from Homo sapiens)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9euo
Q-score: 0.538
Pedersen CN, Yang F, Ita S, Xu Y, Akunuri R, Trampari S, Neumann CMT, Desdorf LM, Schiott B, Salvino JM, Mortensen OV, Nissen P, Shahsavar A
J.Neurochem. (2024) 168 pp. 2043-2055 [ Pubmed: 39010681 DOI: doi:10.1111/jnc.16179 ]
- Chloride ion (35 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Tris-hydroxymethyl-methyl-ammonium (122 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- 9d5 antibody, heavy chain (25 kDa, Protein from Mus musculus)
- N-[3-(6-chloranyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl)propyl]butanamide (333 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Drosophila melanogaster dopamine transporter bound to atypical inhibitor ac-4-248 and in complex with fab 9d5 (85 kDa, Complex from Drosophila melanogaster)
- 9d5 antibody, light chain (25 kDa, Protein from Mus musculus)
- Sodium-dependent dopamine transporter (60 kDa, Protein from Drosophila melanogaster)
Inhibitor-free outward-open structure of Drosophila dopamine transporter
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9eup
Q-score: 0.544
Pedersen CN, Yang F, Ita S, Xu Y, Akunuri R, Trampari S, Neumann CMT, Desdorf LM, Schiott B, Salvino JM, Mortensen OV, Nissen P, Shahsavar A
J.Neurochem. (2024) 168 pp. 2043-2055 [ Pubmed: 39010681 DOI: doi:10.1111/jnc.16179 ]
- Cholesterol (386 Da, Ligand)
- Sodium-dependent dopamine transporter (60 kDa, Protein from Drosophila melanogaster)
- Chloride ion (35 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- 9d5 antibody, heavy chain (25 kDa, Protein from Mus musculus)
- 9d5 antibody, light chain (25 kDa, Protein from Mus musculus)
- Inhibitor-free drosophila melanogaster dopamine transporter in complex with fab 9d5 (107 kDa, Complex from Drosophila melanogaster)
- Sodium ion (22 Da, Ligand)
- Tris-hydroxymethyl-methyl-ammonium (122 Da, Ligand)
Structure of human NuA4/TIP60 complex
Resolution: 9.4 Å
EM Method: Single-particle
Fitted PDBs: 8xvg
Q-score: 0.057
Chen K, Wang L, Yu Z, Yu J, Ren Y, Wang Q, Xu Y
Nat Commun (2024) 15 pp. 7092-7092 [ Pubmed: 39154037 DOI: doi:10.1038/s41467-024-51259-z ]
- Ruvb-like 1 (50 kDa, Protein from Homo sapiens)
- Isoform 2 of enhancer of polycomb homolog 1 (90 kDa, Protein from Homo sapiens)
- Inositol hexakisphosphate (660 Da, Ligand)
- Actb protein (fragment) (41 kDa, Protein from Homo sapiens)
- Ruvb-like 2 (51 kDa, Protein from Homo sapiens)
- Actin-like protein 6a (47 kDa, Protein from Homo sapiens)
- Dna methyltransferase 1-associated protein 1 (53 kDa, Protein from Homo sapiens)
- Isoform 2 of transformation/transcription domain-associated protein (434 kDa, Protein from Homo sapiens)
- Isoform 2 of e1a-binding protein p400 (340 kDa, Protein from Homo sapiens)
- Vacuolar protein sorting-associated protein 72 homolog (40 kDa, Protein from Homo sapiens)
- Structure of human nua4/tip60 complex (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)