Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 8z86
Q-score: 0.452
Chen Z, Feng L, Wang L, Zhang L, Zheng B, Fu H, Li F, Liu L, Lv Q, Deng R, Xu Y, Hu Y, Zheng J, Qin C, Bao L, Wang X, Jin Q
Signal Transduct Target Ther (2025) 10 pp. 14-14 [ DOI: doi:10.1038/s41392-024-02114-6 Pubmed: 39800731 ]
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cr9 heavy chain (12 kDa, Protein from Homo sapiens)
- Cr9 light chain (11 kDa, Protein from Homo sapiens)
- Ba.5 rbd in complex with cr9 (Complex from Homo sapiens)
IAPP S20G lag-phase fibril polymorph 2PF-P
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8awt
Q-score: 0.603
Wilkinson M, Xu Y, Thacker D, Taylor AIP, Fisher DG, Gallardo RU, Radford SE, Ranson NA
Cell (2023) 186 pp. 5798-5811.e26 [ DOI: doi:10.1016/j.cell.2023.11.025 Pubmed: 38134875 ]
IAPP S20G growth-phase fibril polymorph 2PF-L
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8az0
Q-score: 0.53
Wilkinson M, Xu Y, Thacker D, Taylor AIP, Fisher DG, Gallardo RU, Radford SE, Ranson NA
Cell (2023) 186 pp. 5798-5811.e26 [ DOI: doi:10.1016/j.cell.2023.11.025 Pubmed: 38134875 ]
IAPP S20G growth-phase fibril polymorph 2PF-C
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8az1
Q-score: 0.546
Wilkinson M, Xu Y, Thacker D, Taylor AIP, Fisher DG, Gallardo RU, Radford SE, Ranson NA
Cell (2023) 186 pp. 5798-5811.e26 [ DOI: doi:10.1016/j.cell.2023.11.025 Pubmed: 38134875 ]
IAPP S20G plateau-phase fibril polymorph 2PF-L
Resolution: 2.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8az4
Q-score: 0.702
Wilkinson M, Xu Y, Thacker D, Taylor AIP, Fisher DG, Gallardo RU, Radford SE, Ranson NA
Cell (2023) 186 pp. 5798-5811.e26 [ Pubmed: 38134875 DOI: doi:10.1016/j.cell.2023.11.025 ]
- Islet amyloid polypeptide (3 kDa, Protein from Homo sapiens)
- Iapp s20g plateau-phase fibril polymorph 2pf-l (Complex from Homo sapiens)
- Water (18 Da, Ligand)
Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8bfa
Q-score: 0.539
Leistner C, Wilkinson M, Burgess A, Lovatt M, Goodbody S, Xu Y, Deuchars S, Radford SE, Ranson NA, Frank RAW
Nat Commun (2023) 14 pp. 2833-2833 [ Pubmed: 37198197 DOI: doi:10.1038/s41467-023-38495-5 ]
- Sarkosyl-extracted appnl-g-f abeta42 fibril (4 MDa, Complex from Mus musculus)
- Amyloid-beta precursor protein (4 kDa, Protein from Mus musculus)
Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure (Methoxy-X04-labelled mice)
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8bfb
Q-score: 0.581
Leistner C, Wilkinson M, Burgess A, Lovatt M, Goodbody S, Xu Y, Deuchars S, Radford SE, Ranson NA, Frank RAW
Nat Commun (2023) 14 pp. 2833-2833 [ DOI: doi:10.1038/s41467-023-38495-5 Pubmed: 37198197 ]
- Amyloid-beta precursor protein (4 kDa, Protein from Mus musculus)
- Sarkosyl-extracted appnl-g-f abeta42 fibril (4 MDa, Complex from Mus musculus)
Cryo-EM structure of the SPE-mTAAR9 complex
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8iwe
Q-score: 0.493
Guo L, Cheng J, Lian S, Liu Q, Lu Y, Zheng Y, Zhu K, Zhang M, Kong Y, Zhang C, Rong N, Zhuang Y, Fang G, Jiang J, Zhang T, Han X, Liu Z, Xia M, Liu S, Zhang L, Liberles SD, Yu X, Xu Y, Yang F, Li Q, Sun JP
Nature (2023) 618 pp. 193-200 [ DOI: doi:10.1038/s41586-023-06106-4 Pubmed: 37225986 ]
- Trace amine-associated receptor 9 (38 kDa, Protein from Mus musculus)
- Spermidine (145 Da, Ligand)
- Cryo-em structure of the spe-bound mtaar9 complex (Complex from Mus musculus)
Cryo-EM structure of the PEA-bound mTAAR9 complex
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 8iwm
Q-score: 0.491
Guo L, Cheng J, Lian S, Liu Q, Lu Y, Zheng Y, Zhu K, Zhang M, Kong Y, Zhang C, Rong N, Zhuang Y, Fang G, Jiang J, Zhang T, Han X, Liu Z, Xia M, Liu S, Zhang L, Liberles SD, Yu X, Xu Y, Yang F, Li Q, Sun JP
Nature (2023) 618 pp. 193-200 [ DOI: doi:10.1038/s41586-023-06106-4 Pubmed: 37225986 ]
- Trace amine-associated receptor 9 (38 kDa, Protein from Mus musculus)
- Cryo-em structure of the pea-bound mtaar9 complex (Complex from Mus musculus)
- 2-phenylethylamine (122 Da, Ligand)
Cryo-EM structure of TDP43 core peptide amyloid fiber
Resolution: 3.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 7q3u
Q-score: 0.317
Kumar ST, Nazarov S, Porta S, Maharjan N, Cendrowska U, Kabani M, Finamore F, Xu Y, Lee VM, Lashuel HA
Nat Neurosci (2023) 26 pp. 983-996 [ Pubmed: 37248338 DOI: doi:10.1038/s41593-023-01341-4 ]
- Tar dna-binding protein 43 (8 kDa, Protein from Homo sapiens)
- Helical filament from tdp43 core peptide (Complex from Homo sapiens)