Structure of MPXV B6 and D68 fab complex
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 8xs3
Q-score: 0.424
Zhao R, Wu L, Sun J, Liu D, Han P, Gao Y, Zhang Y, Xu Y, Qu X, Wang H, Chai Y, Chen Z, Gao GF, Wang Q
Nat Commun (2024) 15 pp. 4660-4660 [ Pubmed: 38821921 DOI: doi:10.1038/s41467-024-48312-2 ]
- D68_heavy chain (23 kDa, Protein from Homo sapiens)
- D68_light chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structure of mpxv b6 complexed with d68 fab (Complex from Homo sapiens)
- Protein opg190 (28 kDa, Protein from Monkeypox virus)
Structure of Lassa virus polymerase bound to Z matrix protein
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7ckl
Q-score: 0.343
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w ]
- Ring finger protein z (10 kDa, Protein from Lassa mammarenavirus)
- Lassa virus polymerase in complex with z matrix protein (260 kDa, Complex from Lassa mammarenavirus)
- Manganese (ii) ion (54 Da, Ligand)
- Rna-directed rna polymerase l (253 kDa, Protein from Lassa mammarenavirus)
- Zinc ion (65 Da, Ligand)
Structure of Machupo virus polymerase bound to Z matrix protein (monomeric complex)
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 7ckm
Q-score: 0.491
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w ]
- Ring finger protein z (10 kDa, Protein from Machupo virus)
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo virus)
- Manganese (ii) ion (54 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Machupo virus polymerase in complex with z matrix protein (260 kDa, Complex from Machupo mammarenavirus)
Structure of Machupo virus L polymerase in complex with Z protein and 3'-vRNA (dimeric complex)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7el9
Q-score: 0.415
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w Pubmed: 34127846 ]
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo mammarenavirus)
- Machupo virus polymerase in complex with z martix protein and 3'-vrna in dimeric form. (580 kDa, Complex from Machupo mammarenavirus)
- Machupo virus 3'-vrna promoter (Complex from Machupo mammarenavirus)
- Ring finger protein z (10 kDa, Protein from Machupo mammarenavirus)
- Machupo virus 3'-vrna promoter (6 kDa, RNA from Machupo mammarenavirus)
- Machupo virus polymerase (Complex)
- Manganese (ii) ion (54 Da, Ligand)
- Machupo virus z matrix protein (Complex)
- Zinc ion (65 Da, Ligand)
Structure of Lassa virus polymerase in complex with 3'-vRNA and Z mutant (F36A)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7ela
Q-score: 0.447
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w Pubmed: 34127846 ]
- Ring finger protein z (10 kDa, Protein from Lassa mammarenavirus)
- Lassa virus z protein (Complex)
- 3-'vrna promoter (6 kDa, RNA from Lassa mammarenavirus)
- Lassa virus polymerase (Complex)
- Lassa virus polymerase in complex with 3'-vrna and z mutant (f36a). (270 kDa, Complex from Lassa mammarenavirus)
- Rna-directed rna polymerase l (253 kDa, Protein from Lassa mammarenavirus)
- Manganese (ii) ion (54 Da, Ligand)
- 3-'vrna promoter (Complex from Lassa mammarenavirus)
- Zinc ion (65 Da, Ligand)
Structure of Machupo virus L polymerase in complex with Z protein (dimeric form)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7elb
Q-score: 0.229
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w Pubmed: 34127846 ]
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo mammarenavirus)
- Machupo virus polymerase in complex with z protein (dimeric form). (580 kDa, Complex from Machupo mammarenavirus)
- Ring finger protein z (10 kDa, Protein from Machupo mammarenavirus)
- Machupo virus polymerase (Complex from Machupo mammarenavirus)
- Manganese (ii) ion (54 Da, Ligand)
- Machupo virus z matrix protein (Complex)
- Zinc ion (65 Da, Ligand)
Monomeric complex of MACV L bound to Z and 3'-vRNA
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7elc
Q-score: 0.501
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w Pubmed: 34127846 ]
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo mammarenavirus)
- Zinc ion (65 Da, Ligand)
- Machupo virus polymerse (Complex from Machupo mammarenavirus)
- Ring finger protein z (10 kDa, Protein from Machupo mammarenavirus)
- Machupo virus polymerase in complex with z matrix protein and 3'-vrna in monomeric form (270 kDa, Complex from Machupo mammarenavirus)
- 3'-vrna promoter (6 kDa, RNA from Machupo mammarenavirus)
- Manganese (ii) ion (54 Da, Ligand)
- 3'-vrna promoter (Complex)
- Machupo virus z martix protein (Complex)
Structure of LbCas12a-crRNA complex bound to AcrVA4 (form A complex)
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 6kl9
Q-score: 0.434
Peng R, Li Z, Xu Y, He S, Peng Q, Wu LA, Wu Y, Qi J, Wang P, Shi Y, Gao GF
PNAS (2019) 116 pp. 18928-18936 [ Pubmed: 31467167 DOI: doi:10.1073/pnas.1909400116 ]
- Lbcas12a (143 kDa, Protein from Lachnospiraceae bacterium)
- Water (18 Da, Ligand)
- Rna (42-mer) (13 kDa, RNA from synthetic construct)
- Magnesium ion (24 Da, Ligand)
- Lbcas12a-crrna complex bound to acrva4 (form a complex) (170 kDa, Complex from Lachnospiraceae bacterium)
- Acrva4 (27 kDa, Protein from Moraxella bovoculi)
Structure of LbCas12a-crRNA complex bound to AcrVA4 (form B complex)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6klb
Q-score: 0.224
Peng R, Li Z, Xu Y, He S, Peng Q, Wu LA, Wu Y, Qi J, Wang P, Shi Y, Gao GF
PNAS (2019) 116 pp. 18928-18936 [ Pubmed: 31467167 DOI: doi:10.1073/pnas.1909400116 ]
- Lbcas12a (143 kDa, Protein from Lachnospiraceae bacterium)
- Water (18 Da, Ligand)
- Lbcas12a-crrna complex bound to acrva4 (form b complex) (300 kDa, Complex from Lachnospiraceae bacterium)
- Magnesium ion (24 Da, Ligand)
- Acrva4 (27 kDa, Protein from Moraxella bovoculi)
- Crrna (13 kDa, RNA from synthetic construct)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 5xlo
Q-score: 0.337
Peng R, Xu Y, Zhu T, Li N, Qi J, Chai Y, Wu M, Zhang X, Shi Y, Wang P, Wang J, Gao N, Gao GF
Cell Res (2017) 27 pp. 853-864 [ DOI: doi:10.1038/cr.2017.79 Pubmed: 28574055 ]
- Uncharacterized protein acrf1 (8 kDa, Protein from Pseudomonas phage JBD30)
- Anti-crispr proteins acrf1/2 bound to csy surveillance complex with a 32nt spacer crrna backbone region (400 kDa, Complex from Pseudomonas aeruginosa (strain UCBPP-PA14))
- Crrna with 32nt spacer sequence (19 kDa, RNA from Pseudomonas aeruginosa)
- Crispr-associated protein csy3 (Complex)
- Acrf1 (Complex)
- Crrna with 20nt spacer sequence (Complex)
- Crispr-associated protein csy3 (37 kDa, Protein from Pseudomonas aeruginosa (strain UCBPP-PA14))