Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 8yak
Q-score: 0.652
Hu Y, Dai L, Xu Y, Niu D, Yang X, Xie Z, Shen P, Li X, Li H, Zhang L, Min J, Guo RT, Chen CC
Int J Biol Macromol (2024) 278 pp. 134831-134831 [ Pubmed: 39163957 DOI: doi:10.1016/j.ijbiomac.2024.134831 ]
- Pwadh-g88d-d344n (Complex from Pseudoxanthomonas wuyuanensis)
- (2~{s})-2-[[(3~{r})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid (403 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Imidazolonepropionase (43 kDa, Protein from Pseudoxanthomonas wuyuanensis)
Cryo-electron microscopic structure of an amide hydrolase from Pseudoxanthomonas wuyuanensis
Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 8yag
Q-score: 0.665
Hu Y, Dai L, Xu Y, Niu D, Yang X, Xie Z, Shen P, Li X, Li H, Zhang L, Min J, Guo RT, Chen CC
Int J Biol Macromol (2024) 278 pp. 134831-134831 [ Pubmed: 39163957 DOI: doi:10.1016/j.ijbiomac.2024.134831 ]
- Imidazolonepropionase (43 kDa, Protein from Pseudoxanthomonas wuyuanensis)
- Pwadh (Complex from Pseudoxanthomonas wuyuanensis)
- Zinc ion (65 Da, Ligand)
Structure of nanobody-bound DRD1_LSD complex
Fan L, Zhuang Y, Wu H, Li H, Xu Y, Wang Y, He L, Wang S, Chen Z, Cheng J, Xu HE, Wang S
Neuron (2024) 112 pp. 3295- [ DOI: doi:10.1016/j.neuron.2024.07.003 Pubmed: 39094559 ]
- Fab 8d3 (Complex from Mus musculus)
- Prac-prad-prg (Complex from Escherichia coli O157:H7)
- (8alpha)-n,n-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide (323 Da, Ligand)
- Drd1 (Complex from Homo sapiens)
- Nanobody-bound drd1_lsd complex (170 kDa, Complex)
- Nba3 (13 kDa, Protein from Homo sapiens)
- Maltose/maltodextrin-binding periplasmic protein,immunoglobulin g-binding protein a,immunoglobulin g-binding protein g (60 kDa, Protein from Streptococcus sp. 'group G')
- Fab 8d3 light chain (26 kDa, Protein from Mus musculus)
- Fab 8d3 heavy chain (27 kDa, Protein from Mus musculus)
- D(1a) dopamine receptor (39 kDa, Protein from Homo sapiens)
Structure of nanobody-bound DRD1_PF-6142 complex
Fan L, Zhuang Y, Wu H, Li H, Xu Y, Wang Y, He L, Wang S, Chen Z, Cheng J, Xu HE, Wang S
Neuron (2024) 112 pp. 3295- [ DOI: doi:10.1016/j.neuron.2024.07.003 Pubmed: 39094559 ]
- 4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine (356 Da, Ligand)
- Maltose/maltodextrin-binding periplasmic protein,immunoglobulin g-binding protein a,immunoglobulin g-binding protein g (60 kDa, Protein from Staphylococcus aureus)
- Nanobody-bound drd1_pf-6142 complex (170 kDa, Complex)
- Drd1 (Complex from Homo sapiens)
- Prac-prad-prg (Complex from Escherichia coli)
- Nba3 (13 kDa, Protein from Homo sapiens)
- Fab 8d3 light chain (26 kDa, Protein from Mus musculus)
- Fab 8d3 heavy chain (27 kDa, Protein from Mus musculus)
- D(1a) dopamine receptor (39 kDa, Protein from Homo sapiens)
- Fab (Complex from Mus musculus)
Cryo-EM structure of GIPR splice variant 1 (SV1) in complex with Gs protein
Resolution: 3.23 Å
EM Method: Single-particle
Fitted PDBs: 8itl
Q-score: 0.477
Zhao F, Hang K, Zhou Q, Shao L, Li H, Li W, Lin S, Dai A, Cai X, Liu Y, Xu Y, Feng W, Yang D, Wang MW
PNAS (2023) 120 pp. e2306145120-e2306145120 [ Pubmed: 37792509 DOI: doi:10.1073/pnas.2306145120 ]
- Gastric inhibitory polypeptide receptor (42 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Rattus norvegicus)
- Cryo-em structure of a splice variant of the gipr(sv1) in complex with gs protein (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Nanobody-35 (13 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Bos taurus)
Cryo-EM structure of GIPR splice variant 2 (SV2) in complex with Gs protein
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8itm
Q-score: 0.479
Zhao F, Hang K, Zhou Q, Shao L, Li H, Li W, Lin S, Dai A, Cai X, Liu Y, Xu Y, Feng W, Yang D, Wang MW
PNAS (2023) 120 pp. e2306145120-e2306145120 [ Pubmed: 37792509 DOI: doi:10.1073/pnas.2306145120 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Rattus norvegicus)
- Gastric inhibitory polypeptide receptor (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Cryo-em structure of a splice variant of the gipr(sv2) in complex with gs protein (Complex from Homo sapiens)
- Nanobody-35 (13 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Bos taurus)
Cryo-EM structure of the alpha-MSH-bound human melanocortin receptor 5 (MC5R)-Gs complex
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 8inr
Q-score: 0.49
Feng W, Zhou Q, Chen X, Dai A, Cai X, Liu X, Zhao F, Chen Y, Ye C, Xu Y, Cong Z, Li H, Lin S, Yang D, Wang MW
Cell Discov (2023) 9 pp. 81- [ Pubmed: 37524700 DOI: doi:10.1107/S0907444909042073 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1,hibit (40 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Ha signal peptide,melanocortin receptor 5,lgbit subunit (56 kDa, Protein from Homo sapiens)
- Alpha-melanocyte-stimulating hormone (1 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein g(s) subunit alpha isoforms short (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Cryo-em structure of alpha-msh-bound human melanocortin receptor 5 in complex with g protein (Complex from Homo sapiens)
Cryo-EM structure of the gamma-MSH-bound human melanocortin receptor 3 (MC3R)-Gs complex
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8ioc
Q-score: 0.459
Feng W, Zhou Q, Chen X, Dai A, Cai X, Liu X, Zhao F, Chen Y, Ye C, Xu Y, Cong Z, Li H, Lin S, Yang D, Wang MW
Cell Discov (2023) 9 pp. 81- [ Pubmed: 37524700 DOI: doi:10.1107/S0907444909042073 ]
- Gamma-melanocyte-stimulating hormone (1 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Ha signal peptide,melanocortin receptor 3,lgbit subunit (56 kDa, Protein from Homo sapiens)
- Cryo-em structure of gamma-msh-bound human melanocortin receptor 3 in complex with g protein (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein g(s) subunit alpha isoforms short (41 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Nanobody-35 (17 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1,hibit (40 kDa, Protein from Homo sapiens)
Cryo-EM structure of the PG-901-bound human melanocortin receptor 5 (MC5R)-Gs complex
Resolution: 2.59 Å
EM Method: Single-particle
Fitted PDBs: 8iod
Q-score: 0.503
Feng W, Zhou Q, Chen X, Dai A, Cai X, Liu X, Zhao F, Chen Y, Ye C, Xu Y, Cong Z, Li H, Lin S, Yang D, Wang MW
Cell Discov (2023) 9 pp. 81- [ Pubmed: 37524700 DOI: doi:10.1107/S0907444909042073 ]
- Pg-901 (1 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1,hibit (40 kDa, Protein from Homo sapiens)
- Cryo-em structure of pg-901-bound human melanocortin receptor 5 in complex with g protein (Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein g(s) subunit alpha isoforms short (41 kDa, Protein from Homo sapiens)
- Ha signal peptide,melanocortin receptor 5,lgbit subunit (56 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Nanobody-35 (17 kDa, Protein from Homo sapiens)
Cryo-EM structure of the erythromycin-bound motilin receptor-Gq protein complex
Resolution: 3.51 Å
EM Method: Single-particle
Fitted PDBs: 8ibu
Q-score: 0.394
You C, Zhang Y, Xu Y, Xu P, Li Z, Li H, Huang S, Chen Z, Li J, Xu HE, Jiang Y
Sci Adv (2023) 9 pp. eade9020-eade9020 [ Pubmed: 36921049 DOI: doi:10.1126/sciadv.ade9020 ]
- Soluble cytochrome b562,motilin receptor,fusion tag (81 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Erythromycin a (733 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha (41 kDa, Protein from Homo sapiens)
- Erythromycin-bound motilin receptor-gq protein complex (Complex from Homo sapiens)