Cryo-EM structure of the dystrophin glycoprotein complex
Wan L, Ge X, Xu Q, Huang G, Yang T, Campbell KP, Yan Z, Wu J
Nature (2025) 637 pp. 1252-1260 [ Pubmed: 39663450 DOI: doi:10.1038/s41586-024-08310-2 ]
- Zinc ion (65 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Beta-sarcoglycan (28 kDa, Protein from Mus musculus)
- Calcium ion (40 Da, Ligand)
- Unknown segment (559 Da, Protein from Mus musculus)
- Dystrophin glycoprotein complex, dgc (Complex from Mus musculus)
- Dystrophin (38 kDa, Protein from Mus musculus)
- Gamma-sarcoglycan (28 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Delta-sarcoglycan (29 kDa, Protein from Mus musculus)
- Dystrobrevin alpha (23 kDa, Protein from Mus musculus)
- Beta-dystroglycan (31 kDa, Protein from Mus musculus)
- Sarcospan (19 kDa, Protein from Mus musculus)
- Alpha-sarcoglycan (32 kDa, Protein from Mus musculus)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
Cryo-EM structure of the dystrophin glycoprotein complex
Wan L, Ge X, Xu Q, Huang G, Yang T, Campbell KP, Yan Z, Wu J
Nature (2024) [ DOI: doi:10.1038/s41586-024-08310-2 Pubmed: 39663450 ]
FIB-SEM datasets of hippocampal neurons from WT and FAM92A1 knockout mice
Wang L, Yang Z, Satoshi F, Prasanna X, Yan Z, Vihinen H, Chen Y, Zhao Y, He X, Bu Q, Li H, Zhao Y, Jiang L, Qin F, Dai Y, Zhang N, Qin M, Kuang W, Zhao Y, Jokitalo E, Vattulainen I, Kajander T, Zhao H, Cen X
Nat Commun (2024) 15 [ DOI: 10.1038/s41467-024-50565-w Pubmed: 39043703 ]
Image sets:
- FIB-SEM dataset of WT mouse hippocampal neurons (DG region)
- FIB-SEM dataset of hippocampal neurons (DG region) from FAM92A1 KO mouse
- raw FIB-SEM dataset of hippocampal neurons (DG region) from FAM92A1 KO mouse
- raw FIB-SEM dataset of WT mouse hippocampal neurons (DG region)
Cryo-EM Structure of the Arabidopsis thaliana TIC Complex
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8z9y
Q-score: 0.531
Liang K, Jin Z, Zhan X, Li Y, Xu Q, Xie Y, Yang Y, Wang S, Wu J, Yan Z
Cell (2024) 187 pp. 5651-5664.e18 [ DOI: doi:10.1016/j.cell.2024.08.003 Pubmed: 39197452 ]
- Protein tic 100 (100 kDa, Protein from Arabidopsis thaliana)
- Protein tic 56, chloroplastic (61 kDa, Protein from Arabidopsis thaliana)
- Protein tic 214 (214 kDa, Protein from Arabidopsis thaliana)
- Actin t1-like protein (12 kDa, Protein from Arabidopsis thaliana)
- Arabidopsis thaliana tic complex (Complex from Arabidopsis thaliana)
- Protein tic 20-i, chloroplastic (31 kDa, Protein from Arabidopsis thaliana)
- Nucleusenvelope protein (30 kDa, Protein from Arabidopsis thaliana)
The structure of Candida albicans Cdr1 in fluconazole-bound state
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9iul
Q-score: 0.567
Peng Y, Lu Y, Sun H, Ma J, Li X, Han X, Fang Z, Tan J, Qiu Y, Qu T, Yin M, Yan Z
Nat Commun (2024) 15 pp. 7722-7722 [ Pubmed: 39242571 DOI: doi:10.1038/s41467-024-52107-w ]
- 2-(2,4-difluorophenyl)-1,3-di(1h-1,2,4-triazol-1-yl)propan-2-ol (306 Da, Ligand)
- Pip2(20:4/18:0) (1 kDa, Ligand)
- Pleiotropic abc efflux transporter of multiple drugs cdr1 (170 kDa, Protein from Candida albicans SC5314)
- The cryo-em structure of candida albicans cdr1 in fluconazole-bound state (Complex from Candida albicans SC5314)
The structure of Candida albicans Cdr1 in milbemycin oxime-inhibited state
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 9ium
Q-score: 0.547
Peng Y, Lu Y, Sun H, Ma J, Li X, Han X, Fang Z, Tan J, Qiu Y, Qu T, Yin M, Yan Z
Nat Commun (2024) 15 pp. 7722-7722 [ Pubmed: 39242571 DOI: doi:10.1038/s41467-024-52107-w ]
- Milbemycin oxime (555 Da, Ligand)
- The cryo-em structure of candida albicans cdr1 in milbemycin oxime-inhibited state (Complex from Candida albicans SC5314)
- Pip2(20:4/18:0) (1 kDa, Ligand)
- Pleiotropic abc efflux transporter of multiple drugs cdr1 (170 kDa, Protein from Candida albicans SC5314)
The composite EM map of the Ycf2-FtsHi motor complex from Arabidopsis in ATP-bound state
Liang K, Jin Z, Zhan X, Li Y, Xu Q, Xie Y, Yang Y, Wang S, Wu J, Yan Z
Cell (2024) 187 pp. 5651- [ DOI: doi:10.1016/j.cell.2024.08.003 Pubmed: 39197452 ]
- 1,2-dilauroyl-sn-glycero-3-phosphate (535 Da, Ligand)
- Probable inactive atp-dependent zinc metalloprotease ftshi 5, chloroplastic (152 kDa, Protein from Arabidopsis thaliana)
- Aspartyl/glutamyl-trna (asn/gln) amidotransferase subunit b (9 kDa, Protein from Arabidopsis thaliana)
- Unk (1 kDa, Protein from Arabidopsis thaliana)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Malate dehydrogenase, chloroplastic (42 kDa, Protein from Arabidopsis thaliana)
- At4g28210 (38 kDa, Protein from Arabidopsis thaliana)
- Unk (3 kDa, Protein from Arabidopsis thaliana)
- Attam46 (45 kDa, Protein from Arabidopsis thaliana)
- Probable inactive atp-dependent zinc metalloprotease ftshi 2, chloroplastic (100 kDa, Protein from Arabidopsis thaliana)
- Unk (1 kDa, Protein from Arabidopsis thaliana)
- The ycf2-ftshi motor complex from arabidopsis (Complex from Arabidopsis thaliana)
- Probable inactive atp-dependent zinc metalloprotease ftshi 4, chloroplastic (96 kDa, Protein from Arabidopsis thaliana)
- Unk (1 kDa, Protein from Arabidopsis thaliana)
- Atp-dependent zinc metalloprotease ftsh 12, chloroplastic (115 kDa, Protein from Arabidopsis thaliana)
- Protein ycf2 (269 kDa, Protein from Arabidopsis thaliana)
- Probable inactive atp-dependent zinc metalloprotease ftshi 1, chloroplastic (105 kDa, Protein from Arabidopsis thaliana)
- Unk (1 kDa, Protein from Arabidopsis thaliana)
- Zinc ion (65 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Embryo defective 2737 (37 kDa, Protein from Arabidopsis thaliana)