The structure of Candida albicans Cdr1 in fluconazole-bound state
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9iul
Q-score: 0.567
Peng Y, Lu Y, Sun H, Ma J, Li X, Han X, Fang Z, Tan J, Qiu Y, Qu T, Yin M, Yan Z
Nat Commun (2024) 15 pp. 7722-7722 [ DOI: doi:10.1038/s41467-024-52107-w Pubmed: 39242571 ]
- 2-(2,4-difluorophenyl)-1,3-di(1h-1,2,4-triazol-1-yl)propan-2-ol (306 Da, Ligand)
- The cryo-em structure of candida albicans cdr1 in fluconazole-bound state (Complex from Candida albicans SC5314)
- Pip2(20:4/18:0) (1 kDa, Ligand)
- Pleiotropic abc efflux transporter of multiple drugs cdr1 (170 kDa, Protein from Candida albicans SC5314)
The structure of Candida albicans Cdr1 in milbemycin oxime-inhibited state
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 9ium
Q-score: 0.547
Peng Y, Lu Y, Sun H, Ma J, Li X, Han X, Fang Z, Tan J, Qiu Y, Qu T, Yin M, Yan Z
Nat Commun (2024) 15 pp. 7722-7722 [ DOI: doi:10.1038/s41467-024-52107-w Pubmed: 39242571 ]
- The cryo-em structure of candida albicans cdr1 in milbemycin oxime-inhibited state (Complex from Candida albicans SC5314)
- Pleiotropic abc efflux transporter of multiple drugs cdr1 (170 kDa, Protein from Candida albicans SC5314)
- Milbemycin oxime (555 Da, Ligand)
- Pip2(20:4/18:0) (1 kDa, Ligand)
Cryo-EM structure of Chlamydomonas TOC-TIC supercomplex
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7vcf
Q-score: 0.589
Jin Z, Wan L, Zhang Y, Li X, Cao Y, Liu H, Fan S, Cao D, Wang Z, Li X, Pan J, Dong MQ, Wu J, Yan Z
Cell (2022) 185 pp. 4788-4800.e13 [ DOI: doi:10.1016/j.cell.2022.10.030 Pubmed: 36413996 ]
- Tic56 (28 kDa, Protein from Chlamydomonas reinhardtii)
- Toc75 (87 kDa, Protein from Chlamydomonas reinhardtii)
- Toc39 (39 kDa, Protein from Chlamydomonas reinhardtii)
- Tic100 (107 kDa, Protein from Chlamydomonas reinhardtii)
- Tic214 (232 kDa, Protein from Chlamydomonas reinhardtii)
- Ylmg (21 kDa, Protein from Chlamydomonas reinhardtii)
- Toc-tic supercomplex (Complex from Chlamydomonas reinhardtii)
- Tic35 (35 kDa, Protein from Chlamydomonas reinhardtii)
- Inositol hexakisphosphate (660 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tic20-venus-flag (60 kDa, Protein from Chlamydomonas reinhardtii)
- Tic12 (14 kDa, Protein from Chlamydomonas reinhardtii)
- Toc120 (102 kDa, Protein from Chlamydomonas reinhardtii)
- Toc52 (52 kDa, Protein from Chlamydomonas reinhardtii)
- Toc10 (10 kDa, Protein from Chlamydomonas reinhardtii)
- Tic13 (13 kDa, Protein from Chlamydomonas reinhardtii)
- Water (18 Da, Ligand)
- Toc34 (44 kDa, Protein from Chlamydomonas reinhardtii)
- Unknown fragment (2 kDa, Protein from Chlamydomonas reinhardtii)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
Architecture of the human NALCN channelosome
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7wji
Q-score: 0.139
Zhou L, Liu H, Zhao Q, Wu J, Yan Z
Cell Discov (2022) 8 pp. 33-33 [ DOI: doi:10.1038/s41421-022-00392-4 Pubmed: 35387979 ]
- Transmembrane protein fam155a (51 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Nalcn channelosome (900 kDa, Complex from Homo sapiens)
- Protein unc-80 homolog (363 kDa, Protein from Homo sapiens)
- Protein unc-79 homolog (298 kDa, Protein from Homo sapiens)
- Sodium leak channel non-selective protein,extended tegument protein pp150 (229 kDa, Protein from Homo sapiens)
Structure of the human homo-hexameric LRRC8A channel at 4.25 Angstroms
Resolution: 4.25 Å
EM Method: Single-particle
Fitted PDBs: 5zsu
Q-score: 0.27
Kasuya G, Nakane T, Yokoyama T, Jia Y, Inoue M, Watanabe K, Nakamura R, Nishizawa T, Kusakizako T, Tsutsumi A, Yanagisawa H, Dohmae N, Hattori M, Ichijo H, Yan Z, Kikkawa M, Shirouzu M, Ishitani R, Nureki O
Nat Struct Mol Biol (2018) 25 pp. 797-804 [ Pubmed: 30127360 DOI: doi:10.1038/s41594-018-0109-6 ]
