Resolution: 2.11 Å
EM Method: Single-particle
Fitted PDBs: 8z8z
Q-score: 0.589
Xiong Q, Zhu Z, Li T, Li X, Zhou Z, Chao Y, Yang C, Feng S, Qu Q, Li D
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01474-5 Pubmed: 39824977 ]
- Water (18 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (4~{z},7~{z},10~{z},13~{z},16~{z},19~{z})-docosa-4,7,10,13,16,19-hexaenoate (764 Da, Ligand)
- Lychos (127 kDa, Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Lysosomal cholesterol signaling protein,fluorescent protein (127 kDa, Protein from synthetic construct)
Caenorhabditis elegans ACR-23 in betaine and monepantel bound state
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8zfk
Q-score: 0.622
Liu F, Li T, Gong H, Tian F, Bai Y, Wang H, Yang C, Li Y, Guo F, Liu S, Chen Q
EMBO J (2024) 43 pp. 3787-3806 [ DOI: doi:10.1038/s44318-024-00165-7 Pubmed: 39009676 ]
- Water (18 Da, Ligand)
- ~{n}-[(2~{s})-2-cyano-1-[5-cyano-2-(trifluoromethyl)phenoxy]propan-2-yl]-4-(trifluoromethylsulfanyl)benzamide (473 Da, Ligand)
- Betaine receptor acr-23,soluble cytochrome b562 (70 kDa, Protein from Caenorhabditis elegans)
- Acetylcholine receptor like-23(acr-23) (67 kDa, Complex from Caenorhabditis elegans)
- Trimethyl glycine (118 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Caenorhabditis elegans ACR-23 in betaine bound state
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8zfm
Q-score: 0.58
Liu F, Li T, Gong H, Tian F, Bai Y, Wang H, Yang C, Li Y, Guo F, Liu S, Chen Q
EMBO J (2024) 43 pp. 3787-3806 [ DOI: doi:10.1038/s44318-024-00165-7 Pubmed: 39009676 ]
- Trimethyl glycine (118 Da, Ligand)
- Acetylcholine receptor like-23(acr-23) (67 kDa, Complex from Caenorhabditis elegans)
- Water (18 Da, Ligand)
- Betaine receptor acr-23,soluble cytochrome b562 (70 kDa, Protein from Caenorhabditis elegans)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
General transcription factor TFIIH (weak binding)
Resolution: 7.6 Å
EM Method: Single-particle
Fitted PDBs: 7ml3
Q-score: 0.215
Yang C, Fujiwara R, Kim HJ, Basnet P, Zhu Y, Gorbea Colon JJ, Steimle S, Garcia BA, Kaplan CD, Murakami K
Mol Cell (2022) 82 pp. 660-676.e9 [ DOI: doi:10.1016/j.molcel.2021.12.020 Pubmed: 35051353 ]
- General transcription and dna repair factor iih subunit tfb5 (8 kDa, Protein from Saccharomyces cerevisiae)
- General transcription and dna repair factor iih (52 kDa, Protein from Saccharomyces cerevisiae)
- Non-template strand dna (9 kDa, DNA from Saccharomyces cerevisiae)
- Bj4_g0050160.mrna.1.cds.1 (38 kDa, Protein from Saccharomyces cerevisiae)
- General transcription factor tfiih (weak binding) (Complex from Saccharomyces cerevisiae)
- Iron/sulfur cluster (351 Da, Ligand)
- General transcription and dna repair factor iih helicase subunit xpb (95 kDa, Protein from Saccharomyces cerevisiae)
- Template strand dna (9 kDa, DNA from Saccharomyces cerevisiae)
- Tfb1 (58 kDa, Protein from Saccharomyces cerevisiae)
- Rna polymerase ii transcription factor b subunit 2 (58 kDa, Protein from Saccharomyces cerevisiae)
- General transcription and dna repair factor iih helicase subunit xpd (89 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- General transcription and dna repair factor iih subunit tfb4 (37 kDa, Protein from Saccharomyces cerevisiae)