The Cryo-EM structure of MPXV E5 apo conformation
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8xj6
Q-score: 0.362
Zhang W, Liu Y, Yang M, Yang J, Shao Z, Gao Y, Jiang X, Cui R, Zhang Y, Zhao X, Shao Q, Cao C, Li H, Li L, Liu H, Gao H, Gan J
Cell Discov (2024) 10 pp. 67-67 [ DOI: doi:10.1038/s41421-024-00680-1 Pubmed: 38914567 ]
- Monkeypox virus (Virus from Monkeypox virus)
- Amp phosphoramidate (426 Da, Ligand)
- Monkeypox virus e5 (90 kDa, Protein from Monkeypox virus)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Zinc ion (65 Da, Ligand)
The Cryo-EM structure of MPXV E5 in complex with DNA
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 8xj7
Q-score: 0.541
Zhang W, Liu Y, Yang M, Yang J, Shao Z, Gao Y, Jiang X, Cui R, Zhang Y, Zhao X, Shao Q, Cao C, Li H, Li L, Liu H, Gao H, Gan J
Cell Discov (2024) 10 pp. 67-67 [ DOI: doi:10.1038/s41421-024-00680-1 Pubmed: 38914567 ]
- Monkeypox virus (Virus from Monkeypox virus)
- Magnesium ion (24 Da, Ligand)
- Monkeypox virus e5 (90 kDa, Protein from Monkeypox virus)
- Dna (70-mer) (21 kDa, DNA from Monkeypox virus)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
The Cryo-EM structure of MPXV E5 C-terminal in complex with DNA
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 8xj8
Q-score: 0.189
Zhang W, Liu Y, Yang M, Yang J, Shao Z, Gao Y, Jiang X, Cui R, Zhang Y, Zhao X, Shao Q, Cao C, Li H, Li L, Liu H, Gao H, Gan J
Cell Discov (2024) 10 pp. 67-67 [ DOI: doi:10.1038/s41421-024-00680-1 Pubmed: 38914567 ]
- Monkeypox virus (Virus from Monkeypox virus)
- Monkeypox virus e5 (53 kDa, Protein from Monkeypox virus)
- Magnesium ion (24 Da, Ligand)
- Dna (70-mer) (21 kDa, DNA from Monkeypox virus)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Cryo-EM structure of the Cas13bt3-crRNA-target RNA ternary complex in activated state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8fti
Q-score: 0.411
Deng X, Osikpa E, Yang J, Oladeji SJ, Smith J, Gao X, Gao Y
Nat Commun (2023) 14 pp. 5845-5845 [ DOI: doi:10.1038/s41467-023-41501-5 Pubmed: 37730702 ]
- Crrna-linker-target hairpin rna (Complex)
- Integrase (90 kDa, Protein from Planctomycetota bacterium)
- Ternary complex of cas13bt3 in complex with crrna and 30 nt target rna (123 kDa, Complex from Planctomycetota bacterium)
- Crrna-linker-target hairpin rna (33 kDa, RNA from synthetic construct)
- Integrase (Complex)
Structure of Full-Length AsfvPrimPol in Apo-Form
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8iqh
Q-score: 0.383
Shao Z, Su S, Yang J, Zhang W, Gao Y, Zhao X, Zhang Y, Shao Q, Cao C, Li H, Liu H, Zhang J, Lin J, Ma J, Gan J
Nucleic Acids Res (2023) 51 pp. 9475-9490 [ Pubmed: 37587714 DOI: doi:10.1093/nar/gkad677 ]
- Full-length asfvprimpol alone (1 MDa, Complex from African swine fever virus BA71V)
- Putative primase c962r (111 kDa, Protein from African swine fever virus BA71V)
Structure of Full-Length AsfvPrimPol in Complex-Form
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8iqi
Q-score: 0.393
Shao Z, Su S, Yang J, Zhang W, Gao Y, Zhao X, Zhang Y, Shao Q, Cao C, Li H, Liu H, Zhang J, Lin J, Ma J, Gan J
Nucleic Acids Res (2023) 51 pp. 9475-9490 [ Pubmed: 37587714 DOI: doi:10.1093/nar/gkad677 ]
- Magnesium ion (24 Da, Ligand)
- Dna (Complex)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Full-length asfvprimpol (Complex from African swine fever virus BA71V)
- Putative primase c962r (111 kDa, Protein from African swine fever virus BA71V)
- Dna (32-mer) (9 kDa, DNA from synthetic construct)
- Full-length asfvprimpol in complex with dna and amppnp (660 kDa, Complex)