Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8xr9
Q-score: 0.57
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.31 Å
EM Method: Single-particle
Fitted PDBs: 8xra
Q-score: 0.422
Sun J, Zheng T, Jia M, Wang Y, Yang J, Liu Y, Yang P, Xie Y, Sun H, Tong Q, Li J, Yang J, Fu G, Shi Y, Qi J, Liu W, Liu J, Tian WX, Gao GF, Bi Y
Nat Commun (2024) 15 pp. 10012-10012 [ DOI: doi:10.1038/s41467-024-54374-z Pubmed: 39562538 ]
- Hemagglutinin (56 kDa, Protein from Influenza A virus)
- The structure of influenza h2 human singapore hemagglutinin with avian receptor (Complex from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- N-acetyl-alpha-neuraminic acid (309 Da, Ligand)
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8xhe
Q-score: 0.559
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.39 Å
EM Method: Single-particle
Fitted PDBs: 8xhf
Q-score: 0.585
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.54 Å
EM Method: Single-particle
Fitted PDBs: 8xhg
Q-score: 0.579
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.38 Å
EM Method: Single-particle
Fitted PDBs: 8xhh
Q-score: 0.589
CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8k4s
Q-score: 0.521
Yang J, Zhao T, Fan J, Zou H, Lan G, Guo F, Shi Y, Ke H, Yu H, Yue Z, Wang X, Bai Y, Li S, Liu Y, Wang X, Chen Y, Li Y, Lei X
Cell (2024) 187 pp. 7164-7182.e18 [ DOI: doi:10.1016/j.cell.2024.10.001 Pubmed: 39476841 ]
- (4~{r})-4-[(3~{r},5~{r},8~{r},9~{s},10~{s},12~{s},13~{r},14~{s},17~{r})-10,13-dimethyl-12-oxidanyl-3-phosphonooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{h}-cyclopenta[a]phenanthren-17-yl]pentanoic acid (472 Da, Ligand)
- Gs-mini-gq chimera (28 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,mas-related g-protein coupled receptor member x4,green fluorescent protein (79 kDa, Protein from Aequorea victoria)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (8 kDa, Protein from Homo sapiens)
- Complex of mrgprx4 with gq and agonist dca-3p (Complex from Homo sapiens)
CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P, local
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8kex
Q-score: 0.416
Yang J, Zhao T, Fan J, Zou H, Lan G, Guo F, Shi Y, Ke H, Yu H, Yue Z, Wang X, Bai Y, Li S, Liu Y, Wang X, Chen Y, Li Y, Lei X
Cell (2024) 187 pp. 7164-7182.e18 [ DOI: doi:10.1016/j.cell.2024.10.001 Pubmed: 39476841 ]
- Cryo-em structure of mrgprx4 complex with agonist dca-3p (Complex from Homo sapiens)
- Soluble cytochrome b562,mas-related g-protein coupled receptor member x4,green fluorescent protein (79 kDa, Protein from Aequorea victoria)
- (4~{r})-4-[(3~{r},5~{r},8~{r},9~{s},10~{s},12~{s},13~{r},14~{s},17~{r})-10,13-dimethyl-12-oxidanyl-3-phosphonooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{h}-cyclopenta[a]phenanthren-17-yl]pentanoic acid (472 Da, Ligand)
The Cryo-EM structure of MPXV E5 apo conformation
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8xj6
Q-score: 0.362
Zhang W, Liu Y, Yang M, Yang J, Shao Z, Gao Y, Jiang X, Cui R, Zhang Y, Zhao X, Shao Q, Cao C, Li H, Li L, Liu H, Gao H, Gan J
Cell Discov (2024) 10 pp. 67-67 [ DOI: doi:10.1038/s41421-024-00680-1 Pubmed: 38914567 ]
- Monkeypox virus (Virus from Monkeypox virus)
- Amp phosphoramidate (426 Da, Ligand)
- Monkeypox virus e5 (90 kDa, Protein from Monkeypox virus)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Zinc ion (65 Da, Ligand)
The Cryo-EM structure of MPXV E5 in complex with DNA
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 8xj7
Q-score: 0.541
Zhang W, Liu Y, Yang M, Yang J, Shao Z, Gao Y, Jiang X, Cui R, Zhang Y, Zhao X, Shao Q, Cao C, Li H, Li L, Liu H, Gao H, Gan J
Cell Discov (2024) 10 pp. 67-67 [ DOI: doi:10.1038/s41421-024-00680-1 Pubmed: 38914567 ]
- Monkeypox virus (Virus from Monkeypox virus)
- Magnesium ion (24 Da, Ligand)
- Monkeypox virus e5 (90 kDa, Protein from Monkeypox virus)
- Dna (70-mer) (21 kDa, DNA from Monkeypox virus)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)