Focused refined map of the catalytic module of the Anaphase-promoting complex/cyclosome (APC/C).
Focused refined map of the TPR lobe of the Anaphase-promoting complex/cyclosome (APC/C)
Cenp-A nucleosome in complex with Cenp-C
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 7on1
Q-score: 0.47
Yan K, Yang J, Zhang Z, Barford D
To Be Published
- Cenp-a nucleosome in complex with cenp-c (Complex)
- Bj4_g0007000.mrna.1.cds.1 (27 kDa, Protein from Saccharomyces cerevisiae)
- Bj4_g0006610.mrna.1.cds.1 (62 kDa, Protein from Saccharomyces cerevisiae)
- Histones (Complex from Saccharomyces cerevisiae)
- Histone h4 (11 kDa, Protein from Saccharomyces cerevisiae)
- Dna (123-mer) (38 kDa, DNA from Escherichia coli)
- Kinetochore subunit (Complex from Saccharomyces cerevisiae)
- Histone h2b (14 kDa, Protein from Saccharomyces cerevisiae)
- Dna (152-mer) (45 kDa, DNA from Escherichia coli)
- Dna (152-mer), dna (123-mer) (Complex from Escherichia coli)
- Histone h2a (14 kDa, Protein from Saccharomyces cerevisiae)
Cryo-EM structure of the beclomethasone-bound adhesion receptor GPR97-Go complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7d76
Q-score: 0.526
Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, Wang GY, Tao X, Wen X, Zhong YN, Yang J, Yi F, Yu X, Xu HE, Zhang Y, Sun JP
Nature (2021) 589 pp. 620-626 [ DOI: doi:10.1038/s41586-020-03083-w Pubmed: 33408414 ]
- Adhesion g protein-coupled receptor g3; gpr97 (62 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- (8~{s},9~{r},10~{s},11~{s},13~{s},14~{s},16~{s},17~{r})-9-chloranyl-10,13,16-trimethyl-11,17-bis(oxidanyl)-17-(2-oxidanylethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one (408 Da, Ligand)
- Adhesion g protein-coupled receptor g3; gpr97 (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Go (Complex from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- Guanine nucleotide-binding protein g(o) subunit alpha (25 kDa, Protein from Homo sapiens)
- Beclomethasone-bound adhesion receptor gpr97-go complex (Complex)
Cryo-EM structure of the cortisol-bound adhesion receptor GPR97-Go complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7d77
Q-score: 0.56
Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, Wang GY, Tao X, Wen X, Zhong YN, Yang J, Yi F, Yu X, Xu HE, Zhang Y, Sun JP
Nature (2021) 589 pp. 620-626 [ DOI: doi:10.1038/s41586-020-03083-w Pubmed: 33408414 ]
- Water (18 Da, Ligand)
- Adhesion g protein-coupled receptor g3; gpr97 (62 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Scfv16 (26 kDa, Protein from synthetic construct)
- (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione (362 Da, Ligand)
- Adhesion g protein-coupled receptor g3; gpr97 (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Go (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from synthetic construct)
- Palmitic acid (256 Da, Ligand)
- Cortisol-bound adhesion receptor gpr97-go complex (Complex)
- Guanine nucleotide-binding protein g(o) subunit alpha (25 kDa, Protein from Homo sapiens)
SUMOylated apoAPC/C with repositioned APC2 WHB domain
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 6tnt
Q-score: 0.39
Yatskevich S, Kroonen JS, Alfieri C, Tischer T, Howes AC, Clijsters L, Yang J, Zhang Z, Yan K, Vertegaal ACO, Barford D
Cell Rep (2021) 34 pp. 108929-108929 [ Pubmed: 33789095 DOI: doi:10.1016/j.celrep.2021.108929 ]
- Anaphase-promoting complex subunit 2 (93 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit cdc26 (9 kDa, Protein from Homo sapiens)
- Cell division cycle protein 16 homolog (71 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 13 (8 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 7 (66 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Sumoylated apoapc/c with repositioned apc2 whb domain (Complex)
- Anaphase-promoting complex subunit 4 (92 kDa, Protein from Homo sapiens)
- Cell division cycle protein 27 homolog (91 kDa, Protein from Homo sapiens)
- Cell division cycle protein 23 homolog (68 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 1 (216 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 15 (14 kDa, Protein from Homo sapiens)
- Unidentified peptide (1 kDa, Protein from unidentified)
- Anaphase-promoting complex subunit 11 (9 kDa, Protein from Homo sapiens)
- Unidentified peptide (Complex from unidentified)
- Anaphase-promoting complex subunit 10 (21 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 5 (85 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 16 (11 kDa, Protein from Homo sapiens)
- Body 2 with repositioned apc2 whb domain after multi body refinement (Complex from Homo sapiens)