Cryo-EM structure of CD38 in complex with FTL004
Resolution: 3.86 Å
EM Method: Single-particle
Fitted PDBs: 8il3
Q-score: 0.387
Zhang G, Guo C, Wang Y, Zhang X, Liu S, Qu W, Chen C, Yan L, Yang Z, Zhang Z, Jiang X, Chen X, Liu H, Lai Q, Wei X, Lu Y, Zhao S, Deng H, Wang Y, Yu L, Yu H, Wu Y, Su Z, Chen P, Ren Z, Yu M, Qu F, Luo Y, Gou L, Li Q, Huang Y, Ma F, Yang J
J Hematol Oncol (2022) 15 pp. 177-177 [ Pubmed: 36581954 DOI: doi:10.1186/s13045-022-01395-0 ]
- Light chain (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of cd38 in complex with ftl004 (Complex from Homo sapiens)
- Adp-ribosyl cyclase/cyclic adp-ribose hydrolase 1 (26 kDa, Protein from Homo sapiens)
- Heavy chain (22 kDa, Protein from Homo sapiens)
SARS-CoV-2 S trimer in complex with 1F Fab
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7y7j
Q-score: 0.383
Zhao S, Liu F, Qiu S, Lan Q, Wu Y, Xu W, Ke J, Yang J, Liu X, Wang K, Guo H, Xia S, Zhang F, Wang J, Hu X, Lu L, Jiang S, Zhao S, Liu L, Xie Y, Yang X, Wang H, Zhong G
Protein Cell (2023) 14 pp. 74-78 [ Pubmed: 36726762 DOI: doi:10.1093/procel/pwac042 ]
- Sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 spike glycoprotein complex with 1f fab (Complex)
- 1f fab (Complex from Homo sapiens)
- 1f vh (14 kDa, Protein from Homo sapiens)
- 1f vl (11 kDa, Protein from Homo sapiens)
SARS-CoV-2 RBD in complex with 1F Fab
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7y7k
Q-score: 0.241
Zhao S, Liu F, Qiu S, Lan Q, Wu Y, Xu W, Ke J, Yang J, Liu X, Wang K, Guo H, Xia S, Zhang F, Wang J, Hu X, Lu L, Jiang S, Zhao S, Liu L, Xie Y, Yang X, Wang H, Zhong G
Protein Cell (2023) 14 pp. 74-78 [ Pubmed: 36726762 DOI: doi:10.1093/procel/pwac042 ]
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 rbd complex with 1f fab (Complex)
- 1f fab (Complex from Homo sapiens)
- 1f vh (14 kDa, Protein from Homo sapiens)
- Spike protein s1 (20 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 1f vl (11 kDa, Protein from Homo sapiens)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8e4c
Q-score: 0.232
Dong Y, Pi X, Bartels-Burgahn F, Saltukoglu D, Liang Z, Yang J, Alt FW, Reth M, Wu H
Nature (2022) 612 pp. 156-161 [ DOI: doi:10.1038/s41586-022-05412-7 Pubmed: 36228656 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bcr complex (Complex from Mus musculus)
- B-cell antigen receptor complex-associated protein alpha chain,yellow fluorescent protein (42 kDa, Protein from Mus musculus)
- Isoform 2 of immunoglobulin heavy constant mu (45 kDa, Protein from Mus musculus)
- B-cell antigen receptor complex-associated protein beta chain (25 kDa, Protein from Mus musculus)
SARS-CoV-2 spike protein in one-RBD weak state after CTSL-treatment
SARS-CoV-2 spike protein in two-RBD weak state after CTSL-treatment
Cryo-EM structure of the beclomethasone-bound adhesion receptor GPR97-Go complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7d76
Q-score: 0.526
Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, Wang GY, Tao X, Wen X, Zhong YN, Yang J, Yi F, Yu X, Xu HE, Zhang Y, Sun JP
Nature (2021) 589 pp. 620-626 [ Pubmed: 33408414 DOI: doi:10.1038/s41586-020-03083-w ]
- Go (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Adhesion g protein-coupled receptor g3; gpr97 (62 kDa, Protein from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- Guanine nucleotide-binding protein g(o) subunit alpha (25 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Beclomethasone-bound adhesion receptor gpr97-go complex (Complex)
- Adhesion g protein-coupled receptor g3; gpr97 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- (8~{s},9~{r},10~{s},11~{s},13~{s},14~{s},16~{s},17~{r})-9-chloranyl-10,13,16-trimethyl-11,17-bis(oxidanyl)-17-(2-oxidanylethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one (408 Da, Ligand)
- Cholesterol (386 Da, Ligand)
Cryo-EM structure of the cortisol-bound adhesion receptor GPR97-Go complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7d77
Q-score: 0.56
Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, Wang GY, Tao X, Wen X, Zhong YN, Yang J, Yi F, Yu X, Xu HE, Zhang Y, Sun JP
Nature (2021) 589 pp. 620-626 [ Pubmed: 33408414 DOI: doi:10.1038/s41586-020-03083-w ]
- Go (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Adhesion g protein-coupled receptor g3; gpr97 (62 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from synthetic construct)
- Palmitic acid (256 Da, Ligand)
- Cortisol-bound adhesion receptor gpr97-go complex (Complex)
- Scfv16 (Complex from synthetic construct)
- Guanine nucleotide-binding protein g(o) subunit alpha (25 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione (362 Da, Ligand)
- Adhesion g protein-coupled receptor g3; gpr97 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Cholesterol (386 Da, Ligand)