Cryo-EM structure of E. coli RNAP sigma32 complex
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 8hkc
Q-score: 0.582
Lu Q, Chen T, Wang J, Wang F, Ye W, Ma L, Wu S
Biomolecules (2023) 13 [ Pubmed: 37238608 DOI: doi:10.3390/biom13050738 ]
- Dna-directed rna polymerase subunit alpha (36 kDa, Protein from Escherichia coli K-12)
- Cryo-em structure of e. coli rnap sigma32 complex (Complex from Escherichia coli K-12)
- Dna-directed rna polymerase subunit beta' (157 kDa, Protein from Escherichia coli K-12)
- Magnesium ion (24 Da, Ligand)
- Rna polymerase sigma factor rpoh (32 kDa, Protein from Escherichia coli K-12)
- Dna (54-mer) (16 kDa, DNA from Escherichia coli)
- Dna-directed rna polymerase subunit beta (151 kDa, Protein from Escherichia coli K-12)
- Dna (54-mer) (16 kDa, DNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
Human Kv4.2-KChIP2 channel complex in an open state, transmembrane region
Human Kv4.2-KChIP2 channel complex in an inactivated state, class 1, transmembrane region
Human Kv4.2-KChIP2 channel complex in an inactivated state, class 2, transmembrane region
Human Kv4.2-KChIP2 channel complex in an intermediate state, transmembrane region
Human Kv4.2-KChIP2 channel complex in a putative resting state, transmembrane region
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 7ukf
Q-score: 0.478
Ye W, Zhao H, Dai Y, Wang Y, Lo YH, Jan LY, Lee CH
Mol Cell (2022) 82 pp. 2427- [ DOI: doi:10.1016/j.molcel.2022.04.032 Pubmed: 35597238 ]
- Potassium voltage-gated channel subfamily d member 2 (59 kDa, Protein from Homo sapiens)
- Human kv4.2-kchip2 channel complex in a putative resting state, transmembrane region (Complex from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Mercury (ii) ion (200 Da, Ligand)
Human Kv4.2-KChIP2-DPP6 channel complex in an open state, transmembrane region
Resolution: 2.24 Å
EM Method: Single-particle
Fitted PDBs: 7ukg
Q-score: 0.636
Ye W, Zhao H, Dai Y, Wang Y, Lo YH, Jan LY, Lee CH
Mol Cell (2022) 82 pp. 2427- [ Pubmed: 35597238 DOI: doi:10.1016/j.molcel.2022.04.032 ]
- Potassium ion (39 Da, Ligand)
- Potassium voltage-gated channel subfamily d member 2 (59 kDa, Protein from Homo sapiens)
- Dipeptidyl-peptidase 6 (91 kDa, Protein from Homo sapiens)
- Human kv4.2-kchip2-dpp6 channel complex in an open state, transmembrane region (Complex from Homo sapiens)
Human Kv4.2-KChIP2-DPP6 channel complex in an open state, intracellular region
Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 7ukh
Q-score: 0.607
Ye W, Zhao H, Dai Y, Wang Y, Lo YH, Jan LY, Lee CH
Mol Cell (2022) 82 pp. 2427- [ Pubmed: 35597238 DOI: doi:10.1016/j.molcel.2022.04.032 ]
- Human kv4.2-kchip2-dpp6 channel complex in an open state, intracellular region (Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Isoform 2 of kv channel-interacting protein 2 (28 kDa, Protein from Homo sapiens)
- Potassium voltage-gated channel subfamily d member 2 (59 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
cryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134
Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, English JG, DiBerto JF, Olsen RHJ, Huang XP, Zhang S, Liu Y, Kim K, Karpiak J, Jan LY, Abraham SN, Jin J, Shoichet BK, Fay JF, Roth BL
Nature (2021) 600 pp. 170-175 [ Pubmed: 34789874 DOI: 10.1038/s41586-021-04126-6 ]
Image sets:
cryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14
Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, English JG, DiBerto JF, Olsen RHJ, Huang XP, Zhang S, Liu Y, Kim K, Karpiak J, Jan LY, Abraham SN, Jin J, Shoichet BK, Fay JF, Roth BL
Nature (2021) 600 pp. 170-175 [ Pubmed: 34789874 DOI: 10.1038/s41586-021-04126-6 ]
Image sets: