Cryo-EM structure of a SIN3/HDAC complex from budding yeast
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8hpo
Q-score: 0.492
Guo Z, Chu C, Lu Y, Zhang X, Xiao Y, Wu M, Gao S, Wong CCL, Zhan X, Wang C
Nat Struct Mol Biol (2023) [ DOI: doi:10.1038/s41594-023-00975-z Pubmed: 37081318 ]
- Histone deacetylase rpd3 (48 kDa, Protein from Baker's yeast)
- Transcriptional regulatory protein dep1 (47 kDa, Protein from Baker's yeast)
- Transcriptional regulatory protein rxt3 (33 kDa, Protein from Baker's yeast)
- Transcriptional regulatory protein sin3 (175 kDa, Protein from Baker's yeast)
- Zinc ion (65 Da, Ligand)
- The rpd3l complex (Complex from Saccharomyces cerevisiae)
- Phosphothreonine (199 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Transcriptional regulatory protein sap30 (23 kDa, Protein from Baker's yeast)
- Histone deacetylase rpd3 (49 kDa, Protein from Baker's yeast)
- Transcriptional regulatory protein rxt2 (48 kDa, Protein from Baker's yeast)
- Transcriptional regulatory protein pho23 (37 kDa, Protein from Baker's yeast)
- Transcriptional regulatory protein ume1 (51 kDa, Protein from Baker's yeast)
- Transcriptional regulatory protein sds3 (37 kDa, Protein from Baker's yeast)
Cryo-EM structure of the SIN3S complex from S. pombe
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8i02
Q-score: 0.496
Wang C, Guo Z, Chu C, Lu Y, Zhang X, Zhan X
Cell Discov (2023) 9 pp. 42-42 [ DOI: doi:10.1038/s41421-023-00539-x Pubmed: 37076472 ]
- The sin3s complex (Complex from Schizosaccharomyces pombe)
- Cph1 (45 kDa, Protein from Schizosaccharomyces pombe)
- Chromatin modification-related protein eaf3 (39 kDa, Protein from Schizosaccharomyces pombe)
- Uncharacterized protein c2f7.07c (68 kDa, Protein from Schizosaccharomyces pombe)
- Paired amphipathic helix protein pst2 (125 kDa, Protein from Schizosaccharomyces pombe)
- Potassium ion (39 Da, Ligand)
- Histone deacetylase clr6 (46 kDa, Protein from Schizosaccharomyces pombe)
- Rbap48-related wd40 repeat-containing protein prw1 (48 kDa, Protein from Schizosaccharomyces pombe)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of the SIN3L complex from S. pombe
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8i03
Q-score: 0.444
Wang C, Guo Z, Chu C, Lu Y, Zhang X, Zhan X
Cell Discov (2023) 9 pp. 42-42 [ DOI: doi:10.1038/s41421-023-00539-x Pubmed: 37076472 ]
- Transcriptional regulatory protein rxt3 (39 kDa, Protein from Schizosaccharomyces pombe)
- The sin3s complex (Complex from Schizosaccharomyces pombe)
- Transcriptional regulatory protein rxt2 (27 kDa, Protein from Schizosaccharomyces pombe)
- Transcriptional regulatory protein dep1 (55 kDa, Protein from Schizosaccharomyces pombe)
- Potassium ion (39 Da, Ligand)
- Histone deacetylase clr6 (46 kDa, Protein from Schizosaccharomyces pombe)
- Transcriptional regulatory protein sds3 (30 kDa, Protein from Schizosaccharomyces pombe)
- Chromatin modification-related protein png2 (34 kDa, Protein from Schizosaccharomyces pombe)
- Rbap48-related wd40 repeat-containing protein prw1 (48 kDa, Protein from Schizosaccharomyces pombe)
- Zinc ion (65 Da, Ligand)
- Paired amphipathic helix protein pst1 (171 kDa, Protein from Schizosaccharomyces pombe)
- Paired amphipathic helix protein pst3 (133 kDa, Protein from Schizosaccharomyces pombe)
Cryo-EM map of the SIN3L complex from S. pombe in Rxt3 region
Cryo-EM map of the SIN3L complex from S. pombe in Prw1 region