Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7cth
Q-score: 0.421
Sharma A, Zhang X, Dejnirattisai W, Dai X, Gong D, Wongwiwat W, Duquerroy S, Rouvinski A, Vaney MC, Guardado-Calvo P, Haouz A, England P, Sun R, Zhou ZH, Mongkolsapaya J, Screaton GR, Rey FA
Cell (2021) 184 pp. 6052- [ DOI: doi:10.1016/j.cell.2021.11.010 Pubmed: 34852239 ]
- Core protein (8 kDa, Protein from Dengue virus 2)
- Dengue virus (Virus from Dengue virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Core protein (54 kDa, Protein from Dengue virus 2)
- Single chain variable fragment (15 kDa, Protein from Homo sapiens)
- Single chain variable fragment (15 kDa, Protein from Homo sapiens)
Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP
Resolution: 2.82 Å
EM Method: Single-particle
Fitted PDBs: 6z2w
Q-score: 0.479
Tannous EA, Yates LA, Zhang X, Burgers PM
Nat Struct Mol Biol (2021) 28 pp. 50-61 [ DOI: doi:10.1038/s41594-020-00522-0 Pubmed: 33169019 ]
- Water (18 Da, Ligand)
- Mec1-ddc2 (720 kDa, Complex from Saccharomyces cerevisiae S288C)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Serine/threonine-protein kinase mec1 (273 kDa, Protein from Saccharomyces cerevisiae S288C)
- Dna damage checkpoint protein lcd1 (86 kDa, Protein from Saccharomyces cerevisiae S288C)
- Zinc ion (65 Da, Ligand)
Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP (State II)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6z2x
Q-score: 0.418
Tannous EA, Yates LA, Zhang X, Burgers PM
Nat Struct Mol Biol (2021) 28 pp. 50-61 [ DOI: doi:10.1038/s41594-020-00522-0 Pubmed: 33169019 ]
- Mec1-ddc2 (720 kDa, Complex from Saccharomyces cerevisiae S288C)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Serine/threonine-protein kinase mec1 (273 kDa, Protein from Saccharomyces cerevisiae S288C)
- Dna damage checkpoint protein lcd1 (86 kDa, Protein from Saccharomyces cerevisiae S288C)
- Zinc ion (65 Da, Ligand)
Mec1-Ddc2 (wild-type) in complex with AMP-PNP
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6z3a
Q-score: 0.257
Tannous EA, Yates LA, Zhang X, Burgers PM
Nat Struct Mol Biol (2021) 28 pp. 50-61 [ DOI: doi:10.1038/s41594-020-00522-0 Pubmed: 33169019 ]
- Serine/threonine-protein kinase mec1 (273 kDa, Protein from Saccharomyces cerevisiae S288C)
- Mec1-ddc2 (720 kDa, Complex from Saccharomyces cerevisiae S288C)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Dna damage checkpoint protein lcd1 (86 kDa, Protein from Saccharomyces cerevisiae S288C)
- Zinc ion (65 Da, Ligand)
Tannous EA, Yates LA, Zhang X, Burgers PM
Nat Struct Mol Biol (2021) 28 pp. 50-61 [ DOI: doi:10.1038/s41594-020-00522-0 Pubmed: 33169019 ]