Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement)
Resolution: 3.98 Å
EM Method: Single-particle
Fitted PDBs: 8ix3
Q-score: 0.451
Sun H, Wang Y, Chen X, Jiang Y, Wang S, Huang Y, Liu L, Li Y, Lan M, Guo H, Yuan Q, Zhang Y, Li T, Yu H, Gu Y, Zhang J, Li S, Zheng Z, Zheng Q, Xia N
J Virol (2023) 97 pp. e0113723-e0113723 [ Pubmed: 37855619 DOI: doi:10.1128/jvi.01137-23 ]
- Ba.4/5 variant spike protein (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 1g11 (11 kDa, Protein from Homo sapiens)
- Heavy chain of 1g11 (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 ba.4/5 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Nab 1g11 (Complex from Homo sapiens)
- Sars-cov-2 ba.4/5 spike protein in complex with 1g11 (Complex)
Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (state 2)
Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (state 1)
Cryo-EM structure of SARS-CoV-2 spike protein in complex with three nAbs X01, X10 and X17
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 7x7t
Q-score: 0.504
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N
PNAS (2022) 119 pp. e2204256119-e2204256119 [ DOI: doi:10.1073/pnas.2204256119 Pubmed: 35972965 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 spike protein in complex with three nabs x01, x10 and x17 (Complex)
- X01 heavy chain (13 kDa, Protein from Mus musculus)
- Nabs x01, x10 and x17 (Complex from Mus musculus)
- X17 light chain (11 kDa, Protein from Mus musculus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- X17 heavy chain (13 kDa, Protein from Mus musculus)
- X01 light chain (11 kDa, Protein from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- X10 light chain (12 kDa, Protein from Mus musculus)
- X10 heavy chain (13 kDa, Protein from Mus musculus)
Resolution: 3.77 Å
EM Method: Single-particle
Fitted PDBs: 7x7u
Q-score: 0.49
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N
PNAS (2022) 119 pp. e2204256119-e2204256119 [ DOI: doi:10.1073/pnas.2204256119 Pubmed: 35972965 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- X01 heavy chain (13 kDa, Protein from Mus musculus)
- Nabs x01, x10 and x17 (Complex from Mus musculus)
- X10 light chain (12 kDa, Protein from Mus musculus)
- X17 light chain (11 kDa, Protein from Mus musculus)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- X17 heavy chain (13 kDa, Protein from Mus musculus)
- X01 light chain (11 kDa, Protein from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 delta variant spike protein in complex with three nabs x01, x10 and x17 (Complex)
- X10 heavy chain (13 kDa, Protein from Mus musculus)
Cryo-EM structure of SARS-CoV spike protein in complex with three nAbs X01, X10 and X17
Resolution: 3.83 Å
EM Method: Single-particle
Fitted PDBs: 7x7v
Q-score: 0.484
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N
PNAS (2022) 119 pp. e2204256119-e2204256119 [ DOI: doi:10.1073/pnas.2204256119 Pubmed: 35972965 ]
- X01 heavy chain (13 kDa, Protein from Mus musculus)
- Nabs x01, x10 and x17 (Complex from Mus musculus)
- X17 light chain (11 kDa, Protein from Mus musculus)
- X17 heavy chain (13 kDa, Protein from Mus musculus)
- Cryo-em structure of sars-cov spike protein in complex with three nabs x01, x10 and x17 (Complex)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- X01 light chain (11 kDa, Protein from Mus musculus)
- X10 light chain (12 kDa, Protein from Mus musculus)
- X10 heavy chain (13 kDa, Protein from Mus musculus)
- Sars-cov spike protein (Complex from Severe acute respiratory syndrome coronavirus)
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N
PNAS (2022) 119 pp. e2204256119-e2204256119 [ DOI: doi:10.1073/pnas.2204256119 Pubmed: 35972965 ]
Cryo-EM structure of SARS-CoV spike protein in complex with three nAbs X01, X10 and X17
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N
PNAS (2022) 119 pp. e2204256119-e2204256119 [ DOI: doi:10.1073/pnas.2204256119 Pubmed: 35972965 ]
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N
PNAS (2022) 119 pp. e2204256119-e2204256119 [ DOI: doi:10.1073/pnas.2204256119 Pubmed: 35972965 ]
SARS-CoV-2 spike protein in complex with three human neutralizing antibodies
Resolution: 3.42 Å
EM Method: Single-particle
Fitted PDBs: 7whz
Q-score: 0.487
Wang S, Sun H, Zhang Y, Yuan L, Wang Y, Zhang T, Wang S, Zhang J, Yu H, Xiong H, Tang Z, Liu L, Huang Y, Chen X, Li T, Ying D, Liu C, Chen Z, Yuan Q, Zhang J, Cheng T, Li S, Guan Y, Zheng Q, Zheng Z, Xia N
Cell Rep (2022) 39 pp. 110862-110862 [ DOI: doi:10.1016/j.celrep.2022.110862 Pubmed: 35594869 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Xma09 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike protein in complex with three human neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- Ig c934_light_igkv1-5_igkj1 (11 kDa, Protein from Homo sapiens)
- Ig c1437_light_iglv1-40_iglj1 (11 kDa, Protein from Homo sapiens)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Xma04 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Xma01 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Igl c4029_light_igkv1-39_igkj2 (11 kDa, Protein from Homo sapiens)