Cryo-EM structure of prefusion-stabilized RSV F (DS-Cav1 strain: A2) in complex with nAb 5B11
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8wz3
Q-score: 0.525
Liu L, Sun H, Sun Y, Zheng Q, Li S, Zheng Z, Xia N
To Be Published
- Rsv fusion glycoprotein (Complex from Mus musculus)
- 5b11 fab light chain (11 kDa, Protein from Mus musculus)
- 5b11 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rsv fusion glycoprotein (54 kDa, Protein from Human respiratory syncytial virus A2)
- 5b11 fab heavy chain (13 kDa, Protein from Mus musculus)
- Rsv a2 pref in complex with mab 5b11 (Complex from Human respiratory syncytial virus A2)
Spo11 core complex with gapped DNA
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8urq
Q-score: 0.442
Yu Y, Wang J, Liu K, Zheng Z, Arter M, Claeys Bouuaert C, Pu S, Patel DJ, Keeney S
Nat Struct Mol Biol (2025) 32 pp. 113-124 [ DOI: doi:10.1038/s41594-024-01382-8 Pubmed: 39304764 ]
- Meiosis-specific protein spo11 (50 kDa, Protein from Saccharomyces cerevisiae S288C)
- Meiotic recombination protein rec102 (30 kDa, Protein from Saccharomyces cerevisiae S288C)
- Meiotic recombination protein rec104 (20 kDa, Protein from Saccharomyces cerevisiae S288C)
- Gapped dna (21 kDa, DNA from Saccharomyces cerevisiae S288C)
- Spo11 core complex bound to gapped dna (140 kDa, Complex from Saccharomyces cerevisiae S288C)
- Magnesium ion (24 Da, Ligand)
- Antiviral protein ski8 (44 kDa, Protein from Saccharomyces cerevisiae S288C)
Spo11 core complex with hairpin DNA
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8uru
Q-score: 0.419
Yu Y, Wang J, Liu K, Zheng Z, Arter M, Claeys Bouuaert C, Pu S, Patel DJ, Keeney S
Nat Struct Mol Biol (2025) 32 pp. 113-124 [ DOI: doi:10.1038/s41594-024-01382-8 Pubmed: 39304764 ]
- Meiosis-specific protein spo11 (50 kDa, Protein from Saccharomyces cerevisiae S288C)
- Hairpin dna (14 kDa, DNA from Saccharomyces cerevisiae S288C)
- Antiviral protein ski8 (44 kDa, Protein from Saccharomyces cerevisiae S288C)
- Spo11 core complex bound to gapped dna (140 kDa, Complex from Saccharomyces cerevisiae S288C)
- Magnesium ion (24 Da, Ligand)
- Meiotic recombination protein rec104 (20 kDa, Protein from Saccharomyces cerevisiae S288C)
- Meiotic recombination protein rec102 (30 kDa, Protein from Saccharomyces cerevisiae S288C)
Cryo-EM structure of Sr35 resistosome induced by AvrSr35 R381A
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7xx2
Q-score: 0.418
Zhao YB, Liu MX, Chen TT, Ma X, Li ZK, Zheng Z, Zheng SR, Chen L, Li YZ, Tang LR, Chen Q, Wang P, Ouyang S
Sci Adv (2022) 8 pp. eabq5108-eabq5108 [ Pubmed: 36083908 DOI: doi:10.1126/sciadv.abq5108 ]
- Cnl9 (105 kDa, Protein from Triticum monococcum)
- Sr35 resistosome (Complex)
- Avrsr35 (Complex from Puccinia graminis f.sp.tritici)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Sr35 (Complex from Triticum monococcum)
- Avrsr35 (66 kDa, Protein from Puccinia graminis f. sp. tritici)
Cryo-EM structure of plant NLR Sr35 resistosome
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 7xe0
Q-score: 0.351
Zhao YB, Liu MX, Chen TT, Ma X, Li ZK, Zheng Z, Zheng SR, Chen L, Li YZ, Tang LR, Chen Q, Wang P, Ouyang S
Sci Adv (2022) 8 pp. eabq5108-eabq5108 [ Pubmed: 36083908 DOI: doi:10.1126/sciadv.abq5108 ]
- Avrsr35 (Complex from Puccinia graminis f. sp. tritici)
- Sr35 resistosome (Complex)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Sr35 (105 kDa, Protein from Triticum monococcum)
- Sr35 (Complex from Triticum monococcum)
- Avrsr35 (66 kDa, Protein from Puccinia graminis f. sp. tritici)
Cryo-EM structure of SARS-CoV-2 spike protein in complex with three nAbs X01, X10 and X17
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 7x7t
Q-score: 0.504
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N
PNAS (2022) 119 pp. e2204256119-e2204256119 [ DOI: doi:10.1073/pnas.2204256119 Pubmed: 35972965 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 spike protein in complex with three nabs x01, x10 and x17 (Complex)
- X01 heavy chain (13 kDa, Protein from Mus musculus)
- Nabs x01, x10 and x17 (Complex from Mus musculus)
- X17 light chain (11 kDa, Protein from Mus musculus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- X17 heavy chain (13 kDa, Protein from Mus musculus)
- X01 light chain (11 kDa, Protein from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- X10 light chain (12 kDa, Protein from Mus musculus)
- X10 heavy chain (13 kDa, Protein from Mus musculus)
Resolution: 3.77 Å
EM Method: Single-particle
Fitted PDBs: 7x7u
Q-score: 0.49
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N
PNAS (2022) 119 pp. e2204256119-e2204256119 [ DOI: doi:10.1073/pnas.2204256119 Pubmed: 35972965 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- X01 heavy chain (13 kDa, Protein from Mus musculus)
- Nabs x01, x10 and x17 (Complex from Mus musculus)
- X10 light chain (12 kDa, Protein from Mus musculus)
- X17 light chain (11 kDa, Protein from Mus musculus)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- X17 heavy chain (13 kDa, Protein from Mus musculus)
- X01 light chain (11 kDa, Protein from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 delta variant spike protein in complex with three nabs x01, x10 and x17 (Complex)
- X10 heavy chain (13 kDa, Protein from Mus musculus)
SARS-CoV-2 spike protein in complex with three human neutralizing antibodies
Resolution: 3.42 Å
EM Method: Single-particle
Fitted PDBs: 7whz
Q-score: 0.487
Wang S, Sun H, Zhang Y, Yuan L, Wang Y, Zhang T, Wang S, Zhang J, Yu H, Xiong H, Tang Z, Liu L, Huang Y, Chen X, Li T, Ying D, Liu C, Chen Z, Yuan Q, Zhang J, Cheng T, Li S, Guan Y, Zheng Q, Zheng Z, Xia N
Cell Rep (2022) 39 pp. 110862-110862 [ DOI: doi:10.1016/j.celrep.2022.110862 Pubmed: 35594869 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Xma09 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike protein in complex with three human neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- Ig c934_light_igkv1-5_igkj1 (11 kDa, Protein from Homo sapiens)
- Ig c1437_light_iglv1-40_iglj1 (11 kDa, Protein from Homo sapiens)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Xma04 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Xma01 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Igl c4029_light_igkv1-39_igkj2 (11 kDa, Protein from Homo sapiens)
SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies
Resolution: 3.82 Å
EM Method: Single-particle
Fitted PDBs: 7wi0
Q-score: 0.457
Wang S, Sun H, Zhang Y, Yuan L, Wang Y, Zhang T, Wang S, Zhang J, Yu H, Xiong H, Tang Z, Liu L, Huang Y, Chen X, Li T, Ying D, Liu C, Chen Z, Yuan Q, Zhang J, Cheng T, Li S, Guan Y, Zheng Q, Zheng Z, Xia N
Cell Rep (2022) 39 pp. 110862-110862 [ DOI: doi:10.1016/j.celrep.2022.110862 Pubmed: 35594869 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 omicron variant spike in complex with three human neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- Xma09 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Ig c1437_light_iglv1-40_iglj1 (11 kDa, Protein from Homo sapiens)
- Ig c934_light_igkv1-5_igkj1 (11 kDa, Protein from Homo sapiens)
- Xma04 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Xma01 heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Igl c4029_light_igkv1-39_igkj2 (11 kDa, Protein from Homo sapiens)
- Spike protein s1 (22 kDa, Protein from Homo sapiens)