Cryo-EM structure of prefusion-stabilized RSV F (DS-Cav1 strain: A2) in complex with nAb 5B11
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8wz3
Q-score: 0.525
Liu L, Sun H, Sun Y, Zheng Q, Li S, Zheng Z, Xia N
To Be Published
- Rsv fusion glycoprotein (Complex from Mus musculus)
- 5b11 fab light chain (11 kDa, Protein from Mus musculus)
- 5b11 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rsv fusion glycoprotein (54 kDa, Protein from Human respiratory syncytial virus A2)
- 5b11 fab heavy chain (13 kDa, Protein from Mus musculus)
- Rsv a2 pref in complex with mab 5b11 (Complex from Human respiratory syncytial virus A2)
Resolution: 3.51 Å
EM Method: Single-particle
Fitted PDBs: 8wz5
Q-score: 0.418
Liu L, Sun H, Sun Y, Zheng Q, Li S, Zheng Z, Xia N
To Be Published
- 5b11 fab heavy chain (12 kDa, Protein from Mus musculus)
- Rsv fusion glycoprotein (Complex from Human respiratory syncytial virus B)
- Rsv fusion glycoprotein (54 kDa, Protein from Human respiratory syncytial virus B)
- 5b11 fab (Complex from Mus musculus)
- 5b11 fab light chain (11 kDa, Protein from Mus musculus)
- Rsv b18537 pref in complex with humanized mab 5b11 (Complex)
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8wze
Q-score: 0.498
Liu L, Sun H, Sun Y, Zheng Q, Li S, Zheng Z, Xia N
To Be Published
- 5b11 fab heavy chain (12 kDa, Protein from Mus musculus)
- Rsv pre-fusion glycoprotein (Complex from Mus musculus)
- 5b11 fab (Complex)
- Rsv pre-fusion glycoprotein (29 kDa, Protein from Human respiratory syncytial virus B)
- Rsv b18537 pref in complex with mab 5b11 (Complex from Human respiratory syncytial virus B)
- 5b11 fab light chain (11 kDa, Protein from Mus musculus)
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8wz4
Q-score: 0.488
Liu L, Sun H, Sun Y, Zheng Q, Li S, Zheng Z, Xia N
To Be Published
- Rsv fusion glycoprotein (Complex from Mus musculus)
- 5b11 fab light chain (11 kDa, Protein from Mus musculus)
- 5b11 fab (Complex)
- Rsv fusion glycoprotein (54 kDa, Protein from Human respiratory syncytial virus A2)
- 5b11 fab heavy chain (13 kDa, Protein from Mus musculus)
- Rsv a2 pref in complex with mab 5b11 (Complex from Human respiratory syncytial virus A2)
Spo11 core complex with gapped DNA
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8urq
Q-score: 0.442
Yu Y, Wang J, Liu K, Zheng Z, Arter M, Claeys Bouuaert C, Pu S, Patel DJ, Keeney S
Nat Struct Mol Biol (2025) 32 pp. 113-124 [ DOI: doi:10.1038/s41594-024-01382-8 Pubmed: 39304764 ]
- Meiosis-specific protein spo11 (50 kDa, Protein from Saccharomyces cerevisiae S288C)
- Meiotic recombination protein rec102 (30 kDa, Protein from Saccharomyces cerevisiae S288C)
- Meiotic recombination protein rec104 (20 kDa, Protein from Saccharomyces cerevisiae S288C)
- Gapped dna (21 kDa, DNA from Saccharomyces cerevisiae S288C)
- Spo11 core complex bound to gapped dna (140 kDa, Complex from Saccharomyces cerevisiae S288C)
- Magnesium ion (24 Da, Ligand)
- Antiviral protein ski8 (44 kDa, Protein from Saccharomyces cerevisiae S288C)
Spo11 core complex with hairpin DNA
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8uru
Q-score: 0.419
Yu Y, Wang J, Liu K, Zheng Z, Arter M, Claeys Bouuaert C, Pu S, Patel DJ, Keeney S
Nat Struct Mol Biol (2025) 32 pp. 113-124 [ DOI: doi:10.1038/s41594-024-01382-8 Pubmed: 39304764 ]
- Meiosis-specific protein spo11 (50 kDa, Protein from Saccharomyces cerevisiae S288C)
- Hairpin dna (14 kDa, DNA from Saccharomyces cerevisiae S288C)
- Antiviral protein ski8 (44 kDa, Protein from Saccharomyces cerevisiae S288C)
- Spo11 core complex bound to gapped dna (140 kDa, Complex from Saccharomyces cerevisiae S288C)
- Magnesium ion (24 Da, Ligand)
- Meiotic recombination protein rec104 (20 kDa, Protein from Saccharomyces cerevisiae S288C)
- Meiotic recombination protein rec102 (30 kDa, Protein from Saccharomyces cerevisiae S288C)
Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement)
Resolution: 3.98 Å
EM Method: Single-particle
Fitted PDBs: 8ix3
Q-score: 0.451
Sun H, Wang Y, Chen X, Jiang Y, Wang S, Huang Y, Liu L, Li Y, Lan M, Guo H, Yuan Q, Zhang Y, Li T, Yu H, Gu Y, Zhang J, Li S, Zheng Z, Zheng Q, Xia N
J Virol (2023) 97 pp. e0113723-e0113723 [ Pubmed: 37855619 DOI: doi:10.1128/jvi.01137-23 ]
- Ba.4/5 variant spike protein (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 1g11 (11 kDa, Protein from Homo sapiens)
- Heavy chain of 1g11 (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 ba.4/5 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Nab 1g11 (Complex from Homo sapiens)
- Sars-cov-2 ba.4/5 spike protein in complex with 1g11 (Complex)
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7wzr
Q-score: 0.275
Zhang Q, Wang P, Wu T, Zhang Y, Zheng Z, Zhou S, Qian D, Wang X, Cai G
Cell Discov (2022) 8 pp. 98-98 [ Pubmed: 36175395 DOI: doi:10.1038/s41421-022-00461-8 ]
- Dna damage checkpoint protein lcd1 (86 kDa, Protein from Saccharomyces cerevisiae S288C)
- Serine/threonine-protein kinase mec1 (273 kDa, Protein from Saccharomyces cerevisiae S288C)
- Complex of mec1 and ddc2 (359 kDa, Complex from Saccharomyces cerevisiae)
Cryo-EM structure of MEC1-DDC2-MMS
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7wzw
Q-score: 0.227
Zhang Q, Wang P, Wu T, Zhang Y, Zheng Z, Zhou S, Qian D, Wang X, Cai G
Cell Discov (2022) 8 pp. 98-98 [ Pubmed: 36175395 DOI: doi:10.1038/s41421-022-00461-8 ]
- Dna damage checkpoint protein lcd1 (86 kDa, Protein from Saccharomyces cerevisiae S288C)
- Mec1-ddc2 (Complex from Saccharomyces cerevisiae)
- Serine/threonine-protein kinase mec1 (273 kDa, Protein from Saccharomyces cerevisiae S288C)
Cryo-EM structure of Sr35 resistosome induced by AvrSr35 R381A
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7xx2
Q-score: 0.418
Zhao YB, Liu MX, Chen TT, Ma X, Li ZK, Zheng Z, Zheng SR, Chen L, Li YZ, Tang LR, Chen Q, Wang P, Ouyang S
Sci Adv (2022) 8 pp. eabq5108-eabq5108 [ Pubmed: 36083908 DOI: doi:10.1126/sciadv.abq5108 ]
- Cnl9 (105 kDa, Protein from Triticum monococcum)
- Sr35 resistosome (Complex)
- Avrsr35 (Complex from Puccinia graminis f.sp.tritici)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Sr35 (Complex from Triticum monococcum)
- Avrsr35 (66 kDa, Protein from Puccinia graminis f. sp. tritici)