Structure of the native glutamine synthetase in the adult cortex and hippocampus
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ DOI: doi:10.1016/j.cell.2025.01.004 Pubmed: 39855198 ]
- Glutamine synthetase (42 kDa, Protein from Rattus norvegicus)
- Decamer of glutamine synthetase from rat brain (600 MDa, Complex from Rattus norvegicus)
Structure of native tri-heteromeric GluN1-GluN2A-GluN2B NMDA receptor in rat cortex and hippocampus
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8xlk
Q-score: 0.278
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ Pubmed: 39855198 DOI: doi:10.1016/j.cell.2025.01.004 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nmda receptor (Complex)
- Glutamate receptor ionotropic, nmda 2b (166 kDa, Protein from Rattus norvegicus)
- Heavy chain of glun2a fab, 28c (24 kDa, Protein from Mus musculoides)
- Native tri-heteromeric glun1-glun2a-glun2b nmda receptor in rat cortex and hippocampus (Tissue from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (105 kDa, Protein from Rattus norvegicus)
- Light chain of glun2b fab2 (28 kDa, Protein from Mus musculoides)
- Fab 28c (Complex)
- Fab (Complex from Mus musculoides)
- Heavy chain of glun1 fab, 4f11 (15 kDa, Protein from Mus musculoides)
- Light chain of glun2a fab, 28c (22 kDa, Protein from Mus musculoides)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Fab 4f11 (Complex)
- Glutamate receptor ionotropic, nmda 2a (165 kDa, Protein from Rattus norvegicus)
- Light chain of glun1 fab, 4f11 (13 kDa, Protein from Mus musculoides)
- Fab2 (Complex)
- Heavy chain of glun2b fab2 (26 kDa, Protein from Mus musculoides)
Structure of native di-heteromeric GluN1-GluN2B NMDA receptor in rat cortex and hippocampus
Resolution: 5.4 Å
EM Method: Single-particle
Fitted PDBs: 9jnn
Q-score: 0.183
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ Pubmed: 39855198 DOI: doi:10.1016/j.cell.2025.01.004 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of glun2b fab2 (11 kDa, Protein from Mus musculus)
- Native di-heteromeric glun1-glun2b nmda receptor in rat cortex and hippocampus (Tissue)
- Glutamate receptor ionotropic, nmda 2b (91 kDa, Protein from Rattus norvegicus)
- Fab (Complex from Mus musculus)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Rattus norvegicus)
- Light chain of glun1 fab, 4f11 (11 kDa, Protein from Mus musculus)
- Heavy chain of glun2b fab2 (12 kDa, Protein from Mus musculus)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Fab 4f11 (Complex)
- Nmda receptor (Complex from Rattus norvegicus)
- Heavy chain of glun1 fab, 4f11 (13 kDa, Protein from Mus musculus)
- Fab2 (Complex)
SpCas9-MMLV RT-pegRNA-target DNA complex (termination) overall map
SpCas9-MMLV RT-pegRNA-target DNA complex (termination) focused map
SpCas9-MMLV RT-pegRNA-target DNA complex (initiation) overall map
SpCas9-MMLV RT-pegRNA-target DNA complex (initiation) focused map
SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 16-nt) overall map