Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab5F6 in one fab bind conformation
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 8jj0
Q-score: 0.25
Wang H, Xie C, Deng B, Ding J, Li N, Kou Z, Jin M, He J, Wang Q, Wen H, Zhang J, Zhou Q, Chen S, Chen X, Yuan TF, Zhu S
Nat Struct Mol Biol (2024) 31 pp. 1987-1996 [ Pubmed: 39227720 DOI: doi:10.1038/s41594-024-01387-3 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab5f6 light chain (25 kDa, Protein from Homo sapiens)
- Fab5f6 heavy chain (27 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Cryo-em structure of glun1-2a nmdar in complex with human fab23 (Cell from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2a (94 kDa, Protein from Homo sapiens)
Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab2G7 in one fab conformation
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8jj2
Q-score: 0.274
Wang H, Xie C, Deng B, Ding J, Li N, Kou Z, Jin M, He J, Wang Q, Wen H, Zhang J, Zhou Q, Chen S, Chen X, Yuan TF, Zhu S
Nat Struct Mol Biol (2024) 31 pp. 1987-1996 [ Pubmed: 39227720 DOI: doi:10.1038/s41594-024-01387-3 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab2g7 heavy chain (26 kDa, Protein from Homo sapiens)
- Cryo-em structure of glun1-2a nmdar in complex with human fab28 (Cell from Homo sapiens)
- Fab2g7 light chain (25 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2a (94 kDa, Protein from Homo sapiens)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8hdk
Q-score: 0.264
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- Rat glun1-glun2c nmda receptor in complex with glycine and glutamate (Cellular component from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2c (87 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (89 kDa, Protein from Rattus norvegicus)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/CPP bound state
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7eoq
Q-score: 0.288
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ Pubmed: 34186027 DOI: doi:10.1016/j.neuron.2021.05.031 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- Structure of the human glun1/glun2a nmda receptor in the glycine/cpp bound state (Complex from Homo sapiens)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate/GNE-6901 bound state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7eor
Q-score: 0.284
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ Pubmed: 34186027 DOI: doi:10.1016/j.neuron.2021.05.031 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structure of the human glun1/glun2a nmda receptor in the glycine/glutamate/gne-6901 bound state (Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- 7-[(4-fluoranylphenoxy)methyl]-3-[(1~{r},2~{r})-2-(hydroxymethyl)cyclopropyl]-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one (360 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate/GNE-6901/9-AA bound state
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7eou
Q-score: 0.259
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ Pubmed: 34186027 DOI: doi:10.1016/j.neuron.2021.05.031 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- Structure of the human glun1/glun2a nmda receptor in the glycine/glutamate/gne-6901/9-aa bound state (Complex from Homo sapiens)
- 7-[(4-fluoranylphenoxy)methyl]-3-[(1~{r},2~{r})-2-(hydroxymethyl)cyclopropyl]-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one (360 Da, Ligand)
- 9-aminoacridine (195 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
Core region of shut state rabbit ryanodine receptor 1 activated by calcium ion
Wei R, Wang X, Zhang Y, Mukherjee S, Zhang L, Chen Q, Huang X, Jing S, Liu C, Li S, Wang G, Xu Y, Zhu S, Williams AJ, Sun F, Yin CC
Cell Res (2016) 26 pp. 977-994 [ DOI: doi:10.1038/cr.2016.99 Pubmed: 27573175 ]
- Rabbit ryanodine receptor 1 (Protein from Oryctolagus cuniculus)
- Ryanodine receptor 1 (2 MDa, Complex from Oryctolagus cuniculus)
Structure of open state rabbit ryanodine receptor 1 activated by calcium ion
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 5j8v
Q-score: 0.347
Wei R, Wang X, Zhang Y, Mukherjee S, Zhang L, Chen Q, Huang X, Jing S, Liu C, Li S, Wang G, Xu Y, Zhu S, Williams AJ, Sun F, Yin CC
Cell Res (2016) 26 pp. 977-994 [ DOI: doi:10.1038/cr.2016.99 Pubmed: 27573175 ]
- Ryanodine receptor (Protein from Rabbit)
- Ryanodine receptor (2 MDa, Complex from Oryctolagus cuniculus)
Core region of open state rabbit ryanodine receptor 1 activated by calcium ion
Wei R, Wang X, Zhang Y, Mukherjee S, Zhang L, Chen Q, Huang X, Jing S, Liu C, Li S, Wang G, Xu Y, Zhu S, Williams AJ, Sun F, Yin CC
Cell Res (2016) 26 pp. 977-994 [ DOI: doi:10.1038/cr.2016.99 Pubmed: 27573175 ]
- Ryanodine receptor (Protein from Rabbit)
- Ryanodine receptor (2 MDa, Complex from Oryctolagus cuniculus)