Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7yff
Q-score: 0.445
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (94 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glycine (75 Da, Ligand)
Structure of GluN1a-GluN2D NMDA receptor in complex with agonists glycine and glutamate.
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7yfl
Q-score: 0.404
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
- Glycine (75 Da, Ligand)
Structure of GluN1a E698C-GluN2D NMDA receptor in cystines crosslinked state.
Resolution: 6.4 Å
EM Method: Single-particle
Fitted PDBs: 7yfo
Q-score: 0.234
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
Structure of GluN1a E698C-GluN2D NMDA receptor in cystines non-crosslinked state.
Resolution: 5.1 Å
EM Method: Single-particle
Fitted PDBs: 7yfr
Q-score: 0.388
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
- Glycine (75 Da, Ligand)
Structure of GluN1b-GluN2D NMDA receptor in complex with agonists glycine and glutamate.
Resolution: 5.1 Å
EM Method: Single-particle
Fitted PDBs: 7yfm
Q-score: 0.309
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Isoform 6 of glutamate receptor ionotropic, nmda 1 (97 kDa, Protein from Homo sapiens)
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus Zolpidem
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8dd2
Q-score: 0.566
Zhu S, Sridhar A, Teng J, Howard RJ, Lindahl E, Hibbs RE
Nat Commun (2022) 13 pp. 4582-4582 [ Pubmed: 35933426 DOI: doi:10.1038/s41467-022-32212-4 ]
- Igg2b fab heavy chain (49 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Kappa fab light chain (23 kDa, Protein from Mus musculus)
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit alpha-1 (41 kDa, Protein from Homo sapiens)
- Human gabaa receptor alpha1-beta2-gamma2 subtype in complex with gaba plus zolpidem (Complex from Mus musculus)
- Zolpidem (307 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit beta-2 (41 kDa, Protein from Homo sapiens)
- Gamma-aminobutyric acid receptor subunit gamma-2 (47 kDa, Protein from Homo sapiens)
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus DMCM
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8dd3
Q-score: 0.549
Zhu S, Sridhar A, Teng J, Howard RJ, Lindahl E, Hibbs RE
Nat Commun (2022) 13 pp. 4582-4582 [ Pubmed: 35933426 DOI: doi:10.1038/s41467-022-32212-4 ]
- Igg2b fab heavy chain (49 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Kappa fab light chain (23 kDa, Protein from Mus musculus)
- Human gabaa receptor alpha1-beta2-gamma2 subtype in complex with gaba plus dmcm (Complex from Homo sapiens)
- Gamma-aminobutyric acid receptor subunit beta-2 (41 kDa, Protein from Homo sapiens)
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Methyl 4-ethyl-6,7-dimethoxy-9h-pyrido[3,4-b]indole-3-carboxylate (314 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit alpha-1 (41 kDa, Protein from Homo sapiens)
- Gamma-aminobutyric acid receptor subunit gamma-2 (47 kDa, Protein from Homo sapiens)
S protein of SARS-CoV-2 in complex with 2G1
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7x08
Q-score: 0.458
Ma H, Guo Y, Tang H, Tseng CK, Wang L, Zong H, Wang Z, He Y, Chang Y, Wang S, Huang H, Ke Y, Yuan Y, Wu M, Zhang Y, Drelich A, Kempaiah KR, Peng BH, Wang A, Yang K, Yin H, Liu J, Yue Y, Xu W, Zhu S, Ji T, Zhang X, Wang Z, Li G, Liu G, Song J, Mu L, Xiang Z, Song Z, Chen H, Bian Y, Zhang B, Chen H, Zhang J, Liao Y, Zhang L, Yang L, Chen Y, Gilly J, Xiao X, Han L, Jiang H, Xie Y, Zhou Q, Zhu J
Cell Discov (2022) 8 pp. 16-16 [ DOI: doi:10.1038/s41421-022-00381-7 Pubmed: 35169121 ]
- S protein of sars-cov-2 in complex with 2g1 (Complex)
- Light chain of 2g1 (22 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of 2g1 (49 kDa, Protein from Homo sapiens)
- 2g1 (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- Linoleic acid (280 Da, Ligand)
- S protein of sars-cov-2 (Complex from Severe acute respiratory syndrome coronavirus)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/CPP bound state
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7eoq
Q-score: 0.288
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ Pubmed: 34186027 DOI: doi:10.1016/j.neuron.2021.05.031 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- Structure of the human glun1/glun2a nmda receptor in the glycine/cpp bound state (Complex from Homo sapiens)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate/GNE-6901 bound state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7eor
Q-score: 0.284
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ Pubmed: 34186027 DOI: doi:10.1016/j.neuron.2021.05.031 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structure of the human glun1/glun2a nmda receptor in the glycine/glutamate/gne-6901 bound state (Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- 7-[(4-fluoranylphenoxy)methyl]-3-[(1~{r},2~{r})-2-(hydroxymethyl)cyclopropyl]-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one (360 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)