AMC009 SOSIPv5.2 in complex with Fabs ACS114 and ACS122
Resolution: 3.99 Å
EM Method: Single-particle
Fitted PDBs: 7zlk
Q-score: 0.362
van Schooten J, Schorcht A, Farokhi E, Umotoy JC, Gao H, van den Kerkhof TLGM, Dorning J, Rijkhold Meesters TG, van der Woude P, Burger JA, Bijl T, Ghalaiyini R, Torrents de la Pena A, Turner HL, Labranche CC, Stanfield RL, Sok D, Schuitemaker H, Montefiori DC, Burton DR, Ozorowski G, Seaman MS, Wilson IA, Sanders RW, Ward AB, van Gils MJ
PLoS Pathog (2022) 18 pp. e1010945-e1010945 [ DOI: doi:10.1371/journal.ppat.1010945 Pubmed: 36395347 ]
- Acs114 light chain (12 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Amc009 sosipv5.2 envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Amc009 sosipv5.2 in complex with fabs acs114 and acs122 (17 MDa, Complex from Human immunodeficiency virus 1)
- Amc009 sosipv5.2 envelope glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Acs122 heavy chain (13 kDa, Protein from Homo sapiens)
- Acs122 light chain (11 kDa, Protein from Homo sapiens)
- Acs114 heavy chain (13 kDa, Protein from Homo sapiens)
AMC009 SOSIPv5.2 in complex with Fabs ACS101 and ACS124
Resolution: 3.95 Å
EM Method: Single-particle
Fitted PDBs: 7z3a
Q-score: 0.368
van Schooten J, Farokhi E, Schorcht A, van den Kerkhof TLGM, Gao H, van der Woude P, Burger JA, Meesters TGR, Bijl T, Ghalaiyini R, Turner HL, Dorning J, van Schaik BDC, van Kampen AHC, Labranche CC, Stanfield RL, Sok D, Montefiori DC, Burton DR, Seaman MS, Ozorowski G, Wilson IA, Sanders RW, Ward AB, van Gils MJ
Nat Commun (2022) 13 pp. 4515-4515 [ Pubmed: 35922441 DOI: doi:10.1038/s41467-022-32208-0 ]
- Amc009 sosipv5.2 in complex with fabs acs101 and acs124 (Complex from Human immunodeficiency virus 1)
- Acs124 light chain (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Acs124 heavy chain (13 kDa, Protein from Homo sapiens)
- Amc009 sosipv5.2 in complex with fabs acs101 and acs124 (Complex from Homo sapiens)
- Acs101 heavy chain (14 kDa, Protein from Homo sapiens)
- Acs101 light chain (11 kDa, Protein from Homo sapiens)
- Amc009 sosip.v5.2 envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Amc009 sosipv5.2 envelope glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Amc009 sosipv5.2 in complex with fabs acs101 and acs124 (17 MDa, Complex)
BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20J
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 6vo1
Q-score: 0.389
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, Nogal B, Sok D, Rakasz EG, Labranche C, Vigdorovich V, Christley S, Carnathan DG, Sather DN, Montefiori D, Silvestri G, Burton DR, Moore JP, Wilson IA, Sanders RW, Ward AB, van Gils MJ
PLoS Pathog (2020) 16 pp. e1008753-e1008753 [ Pubmed: 32866207 DOI: doi:10.1371/journal.ppat.1008753 ]
- Fab rm20j (Complex from Macaca mulatta)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip.v5.2 in complex with rhesus macaque fab rm20j (Complex)
- Rm20j heavy chain fab (12 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Rm20j kappa light chain (11 kDa, Protein from Macaca mulatta)
- Bg505 sosip.v5.2 (Complex from Human immunodeficiency virus 1)
BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab
Resolution: 4.42 Å
EM Method: Single-particle
Fitted PDBs: 6vlr
Q-score: 0.337
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, Nogal B, Sok D, Rakasz EG, Labranche C, Vigdorovich V, Christley S, Carnathan DG, Sather DN, Montefiori D, Silvestri G, Burton DR, Moore JP, Wilson IA, Sanders RW, Ward AB, van Gils MJ
PLoS Pathog (2020) 16 pp. e1008753-e1008753 [ Pubmed: 32866207 DOI: doi:10.1371/journal.ppat.1008753 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosipv5.2 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 fab light chain (11 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Rm20e1 fab kappa chain (12 kDa, Protein from Macaca mulatta)
- Bg505 sosip.v5.2 in complex with rhesus macaque fab rm20e1 (Complex from Human immunodeficiency virus 1)
- Rm20e1 fab heavy chain (13 kDa, Protein from Macaca mulatta)
- Pgt122 fab heavy chain (14 kDa, Protein from Homo sapiens)
BG505 SOSIP.v4.1 in complex with rhesus macaque Fab RM20F
Resolution: 4.25 Å
EM Method: Single-particle
Fitted PDBs: 6vn0
Q-score: 0.345
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, Nogal B, Sok D, Rakasz EG, Labranche C, Vigdorovich V, Christley S, Carnathan DG, Sather DN, Montefiori D, Silvestri G, Burton DR, Moore JP, Wilson IA, Sanders RW, Ward AB, van Gils MJ
PLoS Pathog (2020) 16 pp. e1008753-e1008753 [ Pubmed: 32866207 DOI: doi:10.1371/journal.ppat.1008753 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip.v4.1 in complex with rhesus macaque fab rm20f (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Rm20f fab heavy chain (13 kDa, Protein from Macaca mulatta)
- Rm20f kappa chain (11 kDa, Protein from Macaca mulatta)