Human GluN1-2A IgG 003-102 splayed conformation
Resolution: 4.42 Å
EM Method: Single-particle
Fitted PDBs: 8vuh
Q-score: 0.204
Michalski K, Abdulla T, Kleeman S, Schmidl L, Gomez R, Simorowski N, Vallese F, Pruss H, Heckmann M, Geis C, Furukawa H
Nat Struct Mol Biol (2024) 31 pp. 1975-1986 [ Pubmed: 39227719 DOI: doi:10.1038/s41594-024-01386-4 ]
- 003-102 heavy (12 kDa, Protein from Homo sapiens)
- Human glun1-2a igg 003-102 splayed conformation (Complex from Homo sapiens)
- 003-102 light (11 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2a (90 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Homo sapiens)
Human GluN1-2A with Fab 003-102
Resolution: 3.92 Å
EM Method: Single-particle
Fitted PDBs: 8vuj
Q-score: 0.416
Michalski K, Abdulla T, Kleeman S, Schmidl L, Gomez R, Simorowski N, Vallese F, Pruss H, Heckmann M, Geis C, Furukawa H
Nat Struct Mol Biol (2024) 31 pp. 1975-1986 [ Pubmed: 39227719 DOI: doi:10.1038/s41594-024-01386-4 ]
- 003-102 heavy (12 kDa, Protein from Homo sapiens)
- 003-102 light (11 kDa, Protein from Homo sapiens)
- Human glun1-2a with fab 003-102 (Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2a (90 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Homo sapiens)
Human GluN1-2A with Fab 003-102 Local refinement of ATD
Resolution: 3.83 Å
EM Method: Single-particle
Fitted PDBs: 8vul
Q-score: 0.47
Michalski K, Abdulla T, Kleeman S, Schmidl L, Gomez R, Simorowski N, Vallese F, Pruss H, Heckmann M, Geis C, Furukawa H
Nat Struct Mol Biol (2024) 31 pp. 1975-1986 [ Pubmed: 39227719 DOI: doi:10.1038/s41594-024-01386-4 ]
- Human glun1-2a with fab 003-102 local refinement of atd (Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (41 kDa, Protein from Homo sapiens)
- 003-102 heavy (12 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2a (41 kDa, Protein from Homo sapiens)
- 003-102 light (11 kDa, Protein from Homo sapiens)
Human GluN1-2A with IgG 003-102 WT conformation
Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 8vur
Q-score: 0.41
Michalski K, Abdulla T, Kleeman S, Schmidl L, Gomez R, Simorowski N, Vallese F, Pruss H, Heckmann M, Geis C, Furukawa H
Nat Struct Mol Biol (2024) 31 pp. 1975-1986 [ Pubmed: 39227719 DOI: doi:10.1038/s41594-024-01386-4 ]
- Human glun1-2a with igg 003-102 wt conformation (Complex from Homo sapiens)
- 003-102 heavy (25 kDa, Protein from Homo sapiens)
- 003-102 light (23 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2a (90 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Homo sapiens)
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 8vuy
Q-score: 0.394
Michalski K, Abdulla T, Kleeman S, Schmidl L, Gomez R, Simorowski N, Vallese F, Pruss H, Heckmann M, Geis C, Furukawa H
Nat Struct Mol Biol (2024) 31 pp. 1975-1986 [ Pubmed: 39227719 DOI: doi:10.1038/s41594-024-01386-4 ]
- Rat glun1-2b with fab 003-102 (Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2b (91 kDa, Protein from Rattus norvegicus)
- 003-102 heavy (12 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Rattus norvegicus)
- 003-102 light (11 kDa, Protein from Homo sapiens)
rat GluN1a-2B Fab 003-102 local refinement
Resolution: 3.95 Å
EM Method: Single-particle
Fitted PDBs: 8vvh
Q-score: 0.442
Michalski K, Abdulla T, Kleeman S, Schmidl L, Gomez R, Simorowski N, Vallese F, Pruss H, Heckmann M, Geis C, Furukawa H
Nat Struct Mol Biol (2024) 31 pp. 1975-1986 [ Pubmed: 39227719 DOI: doi:10.1038/s41594-024-01386-4 ]
- Rat glun1a-2b fab 003-102 local refinement (Complex from Homo sapiens)
- 003-102 heavy (12 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2b (40 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (41 kDa, Protein from Rattus norvegicus)
- 003-102 light (11 kDa, Protein from Homo sapiens)