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sample_name:"20S proteasome" AND xref_links:"drugbank"
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20S proteasome from pre1-1

Blm10-20S proteasome complex from pre1-1

Release date: Sept. 11, 2024
Resolution: 2.39 Å
EM Method: Single-particle
Fitted PDBs: 9gbk
Q-score: 0.585

Mark E, Ramos PC, Kayser F, Hockendorff J, Dohmen RJ, Wendler P

Life Sci Alliance (2024) 7 [ Pubmed: 39260885 DOI: doi:10.26508/lsa.202402865 ]

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canine immunoproteasome 20S subunit in complex with compound 1

CryoEM structure of 20S Trichomonas vaginalis proteasome in complex with proteasome inhibitor Salinosporamid A

Release date: April 10, 2024
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8oix
Q-score: 0.581

Silhan J, Fajtova P, Bartosova J, Hurysz BM, Almaliti J, Miyamoto Y, Eckmann L, Gerwick WH, O'Donoghue AJ, Boura E

Nat Commun (2024) 15 pp. 8621-8621 [ DOI: doi:10.1038/s41467-024-53022-w Pubmed: 39366995 ]

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Structure of the Plasmodium falciparum 20S proteasome complexed with inhibitor TDI-8304

Release date: Dec. 20, 2023
Resolution: 2.18 Å
EM Method: Single-particle
Fitted PDBs: 8g6e
Q-score: 0.715

Hsu HC, Li D, Zhan W, Ye J, Liu YJ, Leung A, Qin J, Crespo B, Gamo FJ, Zhang H, Cui L, Roth A, Kirkman LA, Li H, Lin G

Nat Commun (2023) 14 pp. 8302-8302 [ DOI: doi:10.1038/s41467-023-44077-2 Pubmed: 38097652 ]

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Structure of the Plasmodium falciparum 20S proteasome beta-6 A117D mutant complexed with inhibitor WLW-vs

Release date: Dec. 20, 2023
Resolution: 2.58 Å
EM Method: Single-particle
Fitted PDBs: 8g6f
Q-score: 0.645

Hsu HC, Li D, Zhan W, Ye J, Liu YJ, Leung A, Qin J, Crespo B, Gamo FJ, Zhang H, Cui L, Roth A, Kirkman LA, Li H, Lin G

Nat Commun (2023) 14 pp. 8302-8302 [ DOI: doi:10.1038/s41467-023-44077-2 Pubmed: 38097652 ]

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Human PA200-20S proteasome with MG-132

Release date: Nov. 2, 2022
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8cvs
Q-score: 0.559

Human 19S-20S proteasome, state SD2

Release date: Nov. 2, 2022
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8cvt
Q-score: 0.376

Zhao J, Makhija S, Zhou C, Zhang H, Wang Y, Muralidharan M, Huang B, Cheng Y

PNAS (2022) 119 pp. e2207200119-e2207200119 [ DOI: doi:10.1073/pnas.2207200119 Pubmed: 35858375 ]

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