canine immunoproteasome 20S subunit in complex with compound 1
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8yvp
Q-score: 0.64
Arai Y, Shitama H, Yamagishi M, Ono S, Kashima A, Hiraizumi M, Tsuda N, Katayama K, Tanaka K, Koda Y, Kato S, Sakata K, Nureki O, Miyazaki H
Bioorg.Med.Chem. (2024) 109 pp. 117790-117790 [ Pubmed: 38906067 DOI: doi:10.1016/j.bmc.2024.117790 ]
- Threonine (119 Da, Ligand)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Mus musculus)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Mus musculus)
- Proteasome subunit beta type-7 (25 kDa, Protein from Mus musculus)
- Proteasome subunit beta type-2 (22 kDa, Protein from Mus musculus)
- Proteasome subunit beta type-3 (22 kDa, Protein from Mus musculus)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Mus musculus)
- 20s proteasome (Complex from Mus musculus)
- [(~{r})-cyclohexyl-[(1-cyclohexyl-1,2,3-triazol-4-yl)carbonylamino]methyl]boronic acid (334 Da, Ligand)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Mus musculus)
- Proteasome subunit beta type-6 (22 kDa, Protein from Mus musculus)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Mus musculus)
- Proteasome subunit beta type-1 (26 kDa, Protein from Mus musculus)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Mus musculus)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Mus musculus)
- Proteasome subunit beta type-4 (29 kDa, Protein from Mus musculus)
- Proteasome subunit beta type-5 (22 kDa, Protein from Mus musculus)
Akirin2 bound human proteasome
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7nht
Q-score: 0.547
de Almeida M, Hinterndorfer M, Brunner H, Grishkovskaya I, Singh K, Schleiffer A, Jude J, Deswal S, Kalis R, Vunjak M, Lendl T, Imre R, Roitinger E, Neumann T, Kandolf S, Schutzbier M, Mechtler K, Versteeg GA, Haselbach D, Zuber J
Nature (2021) 599 pp. 491-496 [ Pubmed: 34711951 DOI: doi:10.1038/s41586-021-04035-8 ]
- Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
- Akirin-2 (22 kDa, Protein from Homo sapiens)
- Akirin2 bound to 20s proteasome (780 kDa, Complex)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (30 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
- 20s proteasome (Complex from Homo sapiens)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Akirin2 (Complex from Homo sapiens)
- Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)