Structure of Candida albicans 80S ribosome in complex with mefloquine
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8ogj
Q-score: 0.366
Kolosova O, Zgadzay Y, Yusupov M
To Be Published
- 40s ribosomal protein s27 (8 kDa, Protein from Candida albicans)
- 60s ribosomal protein l11-b (19 kDa, Protein from Candida albicans)
- 40s ribosomal protein s6 (27 kDa, Protein from Candida albicans)
- 40s ribosomal protein s18-b (17 kDa, Protein from Candida albicans)
- 60s ribosomal protein l38 (8 kDa, Protein from Candida albicans)
- 40s ribosomal protein s1 (29 kDa, Protein from Candida albicans)
- Candida albicans 80s ribosome in complex with mefloquine (3 MDa, Complex from Candida albicans)
- 60s ribosomal protein l2-b (27 kDa, Protein from Candida albicans)
- Ribosomal protein s23 (s12) (16 kDa, Protein from Candida albicans)
- 40s ribosomal protein s10-a (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s0 (28 kDa, Protein from Candida albicans)
- 60s ribosomal protein l13 (23 kDa, Protein from Candida albicans)
- 60s ribosomal protein l41 (3 kDa, Protein from Candida albicans)
- Mixture of endogenous e-trnas (24 kDa, RNA from Candida albicans)
- 40s ribosomal protein s24 (15 kDa, Protein from Candida albicans)
- 60s ribosomal protein l24-a (17 kDa, Protein from Candida albicans)
- 40s ribosomal protein s25 (11 kDa, Protein from Candida albicans)
- 60s ribosomal protein l28 (16 kDa, Protein from Candida albicans)
- Zinc ion (65 Da, Ligand)
- 18s ribosomal rna (575 kDa, RNA from Candida albicans)
- 60s ribosomal protein l42-b (12 kDa, Protein from Candida albicans)
- 40s ribosomal protein s28-b (7 kDa, Protein from Candida albicans)
- 60s ribosomal protein l3 (44 kDa, Protein from Candida albicans)
- 60s ribosomal protein l29 (7 kDa, Protein from Candida albicans)
- 60s ribosomal protein l9-b (21 kDa, Protein from Candida albicans)
- Spermine (fully protonated form) (206 Da, Ligand)
- 60s ribosomal protein l14-b (14 kDa, Protein from Candida albicans)
- 40s ribosomal protein s8 (22 kDa, Protein from Candida albicans)
- 60s ribosomal protein l23-a (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l39 (6 kDa, Protein from Candida albicans)
- 60s ribosomal protein l36 (11 kDa, Protein from Candida albicans)
- (11r,12s)- mefloquine (378 Da, Ligand)
- 60s ribosomal protein l34-b (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s30 (7 kDa, Protein from Candida albicans)
- 60s ribosomal protein l27 (15 kDa, Protein from Candida albicans)
- 40s ribosomal protein s22-a (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l6 (19 kDa, Protein from Candida albicans)
- 60s ribosomal protein l37-b (10 kDa, Protein from Candida albicans)
- Ribosomal protein l29 (14 kDa, Protein from Candida albicans)
- 40s ribosomal protein s11a (17 kDa, Protein from Candida albicans)
- 40s ribosomal protein s21 (9 kDa, Protein from Candida albicans)
- 5s ribosomal rna (38 kDa, RNA from Candida albicans)
- 25s ribosomal rna (1 MDa, RNA from Candida albicans)
- 40s ribosomal protein s12 (15 kDa, Protein from Candida albicans)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Candida albicans)
- 40s ribosomal protein s14-a (14 kDa, Protein from Candida albicans)
- Ubiquitin-40s ribosomal protein s31 fusion protein (22 kDa, Protein from Candida albicans)
- 60s ribosomal protein l20 (20 kDa, Protein from Candida albicans)
- 60s ribosomal protein l33-a (12 kDa, Protein from Candida albicans)
- 60s ribosomal protein l5 (34 kDa, Protein from Candida albicans)
- 60s ribosomal protein l25 (15 kDa, Protein from Candida albicans)
- Ribosomal protein s5 (26 kDa, Protein from Candida albicans)
- 40s ribosomal protein s16 (15 kDa, Protein from Candida albicans)
- 60s ribosomal protein l7-a (27 kDa, Protein from Candida albicans)
- 40s ribosomal protein s7 (21 kDa, Protein from Candida albicans)
- Ribosomal protein s4 (21 kDa, Protein from Candida albicans)
- Ribosomal protein l24 (14 kDa, Protein from Candida albicans)
- 40s ribosomal protein s19-a (16 kDa, Protein from Candida albicans)
- Ribosomal protein s7 (25 kDa, Protein from Candida albicans)
- Magnesium ion (24 Da, Ligand)
- 40s ribosomal protein s29a (6 kDa, Protein from Candida albicans)
- 60s ribosomal protein l19-a (21 kDa, Protein from Candida albicans)
- Ribosomal protein s3 (27 kDa, Protein from Candida albicans)
- 60s ribosomal protein l31-b (12 kDa, Protein from Candida albicans)
- 60s ribosomal protein l15-a (24 kDa, Protein from Candida albicans)
- 60s ribosomal protein l21-a (18 kDa, Protein from Candida albicans)
- Ribosomal protein l22 (21 kDa, Protein from Candida albicans)
- 40s ribosomal protein s13 (16 kDa, Protein from Candida albicans)
- 60s ribosomal protein l18-a (20 kDa, Protein from Candida albicans)
- 60s ribosomal protein l32 (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l4-b (39 kDa, Protein from Candida albicans)
- 60s ribosomal protein l22-b (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l40-b (6 kDa, Protein from Candida albicans)
- 60s ribosomal protein l10 (25 kDa, Protein from Candida albicans)
- 60s ribosomal protein l43-a (10 kDa, Protein from Candida albicans)
- Ribosomal protein s10 (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s26 (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s4 (29 kDa, Protein from Candida albicans)
- Ribosomal protein l13 (22 kDa, Protein from Candida albicans)
- 40s ribosomal protein s15 (15 kDa, Protein from Candida albicans)
- 40s ribosomal protein s17-b (15 kDa, Protein from Candida albicans)
- 5.8s ribosomal rna (50 kDa, RNA from Candida albicans)
- 60s ribosomal protein l8 (28 kDa, Protein from Candida albicans)
- 60s ribosomal protein l30 (11 kDa, Protein from Candida albicans)
Structure of Candida albicans 80S ribosome in complex with cycloheximide
Resolution: 2.56 Å
EM Method: Single-particle
Fitted PDBs: 7q08
Q-score: 0.517
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D, Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G, Sachs MS, Guskov A, Yusupov M
Sci Adv (2022) 8 pp. eabn1062-eabn1062 [ DOI: doi:10.1126/sciadv.abn1062 Pubmed: 35613268 ]
- Ribosomal 40s subunit protein s11a (17 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l38 (8 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l16a (22 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s29a (6 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l29 (7 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s27 (8 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l10 (25 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s3 (27 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l36 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l21a (18 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s6 (27 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l18a (20 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s1 (29 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l35a (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s23b (16 kDa, Protein from Candida albicans SC5314)
- Ubiquitin-ribosomal 40s subunit protein s31 fusion protein (22 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s28b (7 kDa, Protein from Candida albicans SC5314)
- Rpl40bp (6 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s14b (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s12 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l7a (27 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l9b (21 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s0 (28 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s10a (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s19a (16 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l6 (19 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s25 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l33a (12 kDa, Protein from Candida albicans SC5314)
- Zinc ion (65 Da, Ligand)
- 5.8s ribosomal rna (50 kDa, RNA from Candida albicans SC5314)
- Spermidine (145 Da, Ligand)
- Candida albicans 80s ribosome (3 MDa, Complex from Candida albicans SC5314)
- Ribosomal 40s subunit protein s18b (17 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s22-a (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l19 (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l28 (16 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l34b (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s9b (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l15 (24 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l5 (34 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l17b (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s2 (26 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l43a (10 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l26b (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s21 (9 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s5 (25 kDa, Protein from Candida albicans SC5314)
- 4-{(2r)-2-[(1s,3s,5s)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione (281 Da, Ligand)
- Ribosomal 60s subunit protein l2a (27 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s30 (7 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l27 (15 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein el41 (3 kDa, Protein from Candida albicans SC5314)
- 5s ribosomal rna (38 kDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l22b (14 kDa, Protein from Candida albicans SC5314)
- 18s ribosomal rna (575 kDa, RNA from Candida albicans SC5314)
- Ribosomal 40s subunit protein s17b (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l32 (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s7 (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l11b (19 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l8 (28 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l24a (17 kDa, Protein from Candida albicans SC5314)
- Habp4_pai-rbp1 domain-containing protein (29 kDa, Protein from Candida albicans SC5314)
- 25s ribosomal rna (1 MDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l42a (12 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s13 (16 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l13 (23 kDa, Protein from Candida albicans SC5314)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l20 (20 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l39 (6 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s8 (22 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s4 (29 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l3 (44 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l4b (39 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s26 (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l37 (10 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s16a (15 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s24 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l25 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s20 (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l23b (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l30 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l14b (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s15 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l31b (12 kDa, Protein from Candida albicans SC5314)
Cryo-EM map of the Candida albicans 80S ribosome in complex with blasticidin s
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 7q0r
Q-score: 0.448
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D, Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G, Sachs MS, Guskov A, Yusupov M
Sci Adv (2022) 8 pp. eabn1062-eabn1062 [ DOI: doi:10.1126/sciadv.abn1062 Pubmed: 35613268 ]
- Ribosomal 40s subunit protein s11a (17 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l38 (8 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l16a (22 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s29a (6 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l29 (7 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s27 (8 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l10 (25 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s3 (27 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l36 (11 kDa, Protein from Candida albicans SC5314)
- Mixture of the endogenous e-trna (24 kDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l21a (18 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s6 (27 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l18a (20 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s1 (29 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l35a (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s23b (16 kDa, Protein from Candida albicans SC5314)
- Ubiquitin-ribosomal 40s subunit protein s31 fusion protein (22 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l41 (3 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s28b (7 kDa, Protein from Candida albicans SC5314)
- Rpl40bp (6 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s14b (14 kDa, Protein from Candida albicans SC5314)
- Blasticidin s (422 Da, Ligand)
- 40s ribosomal protein s12 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l7a (27 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l9b (21 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s0 (28 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s10a (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s19a (16 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l6 (19 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s25 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l33a (12 kDa, Protein from Candida albicans SC5314)
- Zinc ion (65 Da, Ligand)
- 5.8s ribosomal rna (50 kDa, RNA from Candida albicans SC5314)
- Spermidine (145 Da, Ligand)
- Candida albicans 80s ribosome (3 MDa, Complex from Candida albicans SC5314)
- Ribosomal 40s subunit protein s18b (17 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s22-a (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l19 (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l28 (16 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l34b (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s9b (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l15 (24 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l5 (34 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l17b (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s2 (26 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l43a (10 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l26b (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s21 (9 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s5 (25 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l2a (27 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s30 (7 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l27 (15 kDa, Protein from Candida albicans SC5314)
- 5s ribosomal rna (38 kDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l22b (14 kDa, Protein from Candida albicans SC5314)
- 18s ribosomal rna (575 kDa, RNA from Candida albicans SC5314)
- Ribosomal 40s subunit protein s17b (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l32 (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s7 (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l11b (19 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l8 (28 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l24a (17 kDa, Protein from Candida albicans SC5314)
- Habp4_pai-rbp1 domain-containing protein (29 kDa, Protein from Candida albicans SC5314)
- 25s ribosomal rna (1 MDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l42a (12 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s13 (16 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l13 (23 kDa, Protein from Candida albicans SC5314)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l20 (20 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l39 (6 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s8 (22 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s4 (29 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l4b (39 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s26 (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l37 (10 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s16a (15 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s24 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l25 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s20 (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l23b (14 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l3 (44 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l30 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l14b (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s15 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l31b (12 kDa, Protein from Candida albicans SC5314)
Cryo-EM map of the vacant Candida albicans 80S ribosome
Resolution: 2.32 Å
EM Method: Single-particle
Fitted PDBs: 7pzy
Q-score: 0.53
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D, Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G, Sachs MS, Guskov A, Yusupov M
Sci Adv (2022) 8 pp. eabn1062-eabn1062 [ DOI: doi:10.1126/sciadv.abn1062 Pubmed: 35613268 ]
- Ribosomal 40s subunit protein s16a (15 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l3 (44 kDa, Protein from Candida albicans SC5314)
- Candida albicans 80s ribosome (3 MDa, Complex from Candida albicans SC5314)
- Ribosomal 60s subunit protein l7a (27 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l25 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l30 (11 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l41 (3 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s30 (7 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l14b (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s29a (6 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s15 (15 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s21 (9 kDa, Protein from Candida albicans SC5314)
- Magnesium ion (24 Da, Ligand)
- Ribosomal 60s subunit protein l4b (39 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s10a (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l18a (20 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l17b (21 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l8 (28 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l19 (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l26b (14 kDa, Protein from Candida albicans SC5314)
- Spermidine (145 Da, Ligand)
- Ribosomal 60s subunit protein l10 (25 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s26 (13 kDa, Protein from Candida albicans SC5314)
- Rpl40bp (6 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l34b (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l24a (17 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l28 (16 kDa, Protein from Candida albicans SC5314)
- 5.8s ribosomal rna (50 kDa, RNA from Candida albicans SC5314)
- 60s ribosomal protein l36 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l11b (19 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s3 (27 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l6 (19 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s5 (25 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s28b (7 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s11a (17 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s24 (15 kDa, Protein from Candida albicans SC5314)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s9b (21 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s27 (8 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s8 (22 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l20 (20 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l33a (12 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l15 (24 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s2 (26 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l39 (6 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l22b (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s14b (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s20 (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s18b (17 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s7 (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s13 (16 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s12 (15 kDa, Protein from Candida albicans SC5314)
- Ubiquitin-ribosomal 40s subunit protein s31 fusion protein (22 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s0 (28 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l27 (15 kDa, Protein from Candida albicans SC5314)
- Water (18 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ribosomal 60s subunit protein l16a (22 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s6 (27 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l23b (14 kDa, Protein from Candida albicans SC5314)
- 25s ribosomal rna (1 MDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l35a (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s23b (16 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l5 (34 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s1 (29 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l13 (23 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l31b (12 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l9b (21 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s25 (11 kDa, Protein from Candida albicans SC5314)
- 18s ribosomal rna (575 kDa, RNA from Candida albicans SC5314)
- Mixture of endogenous e-trnas (24 kDa, RNA from Candida albicans SC5314)
- Ribosomal 40s subunit protein s19a (16 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l32 (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l21a (18 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l43a (10 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s17b (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l38 (8 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l29 (7 kDa, Protein from Candida albicans SC5314)
- Habp4_pai-rbp1 domain-containing protein (29 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l42a (12 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l37 (10 kDa, Protein from Candida albicans SC5314)
- 5s ribosomal rna (38 kDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l2a (27 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s22-a (14 kDa, Protein from Candida albicans SC5314)
- 1,4-diaminobutane (88 Da, Ligand)
- 40s ribosomal protein s4 (29 kDa, Protein from Candida albicans SC5314)
Cryo-EM map of Candida albicans 80S ribosome in complex with phyllanthoside
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 7q0f
Q-score: 0.521
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D, Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G, Sachs MS, Guskov A, Yusupov M
Sci Adv (2022) 8 pp. eabn1062-eabn1062 [ DOI: doi:10.1126/sciadv.abn1062 Pubmed: 35613268 ]
- Ribosomal 40s subunit protein s11a (17 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l38 (8 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l16a (22 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s29a (6 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l29 (7 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s27 (8 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l10 (25 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s3 (27 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l36 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l21a (18 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s6 (27 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l18a (20 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s1 (29 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l35a (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s23b (16 kDa, Protein from Candida albicans SC5314)
- Ubiquitin-ribosomal 40s subunit protein s31 fusion protein (22 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s28b (7 kDa, Protein from Candida albicans SC5314)
- Rpl40bp (6 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s14b (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s12 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l7a (27 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l9b (21 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s0 (28 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s10a (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s19a (16 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l6 (19 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s25 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l33a (12 kDa, Protein from Candida albicans SC5314)
- Zinc ion (65 Da, Ligand)
- Spermidine (145 Da, Ligand)
- Candida albicans 80s ribosome (3 MDa, Complex from Candida albicans SC5314)
- Ribosomal 40s subunit protein s18b (17 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s22-a (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l19 (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l28 (16 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l34b (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s9b (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l15 (24 kDa, Protein from Candida albicans SC5314)
- 5.8s ribosomal rna (50 kDa, RNA from Candida albicans)
- Ribosomal 60s subunit protein l5 (34 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l17b (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s2 (26 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l43a (10 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l26b (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s21 (9 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s5 (25 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l2a (27 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s30 (7 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l27 (15 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein el41 (3 kDa, Protein from Candida albicans SC5314)
- 5s ribosomal rna (38 kDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l22b (14 kDa, Protein from Candida albicans SC5314)
- 18s ribosomal rna (575 kDa, RNA from Candida albicans SC5314)
- Ribosomal 40s subunit protein s17b (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l32 (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s7 (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l11b (19 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l8 (28 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l24a (17 kDa, Protein from Candida albicans SC5314)
- Habp4_pai-rbp1 domain-containing protein (29 kDa, Protein from Candida albicans SC5314)
- 25s ribosomal rna (1 MDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l42a (12 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s13 (16 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l13 (23 kDa, Protein from Candida albicans SC5314)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l20 (20 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l39 (6 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s8 (22 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s4 (29 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l3 (44 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l4b (39 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s26 (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l37 (10 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s16a (15 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s24 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l25 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s20 (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l23b (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l30 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l14b (14 kDa, Protein from Candida albicans SC5314)
- 3-o-acetyl-2-o-(3-o-acetyl-6-deoxy-beta-d-glucopyranosyl)-6-deoxy-1-o-{[(2r,2's,3a'r,4''s,5''r,6's,7a's)-5''-methyl-4''-{[(2e)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-d-glucopyranose (804 Da, Ligand)
- Ribosomal 40s subunit protein s15 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l31b (12 kDa, Protein from Candida albicans SC5314)
Cryo-EM map of the Candida albicans 80S ribosome in complex with anisomycin
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 7q0p
Q-score: 0.41
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D, Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G, Sachs MS, Guskov A, Yusupov M
Sci Adv (2022) 8 pp. eabn1062-eabn1062 [ DOI: doi:10.1126/sciadv.abn1062 Pubmed: 35613268 ]
- Ribosomal 40s subunit protein s11a (17 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l38 (8 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l16a (22 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s29a (6 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l29 (7 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s27 (8 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l10 (25 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s3 (27 kDa, Protein from Candida albicans SC5314)
- Anisomycin (265 Da, Ligand)
- 60s ribosomal protein l36 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l21a (18 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s6 (27 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l18a (20 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s1 (29 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l35a (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s23b (16 kDa, Protein from Candida albicans SC5314)
- Ubiquitin-ribosomal 40s subunit protein s31 fusion protein (22 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l41 (3 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s28b (7 kDa, Protein from Candida albicans SC5314)
- Rpl40bp (6 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s14b (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s12 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l7a (27 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l9b (21 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s0 (28 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s10a (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s19a (16 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l6 (19 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s25 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l33a (12 kDa, Protein from Candida albicans SC5314)
- Zinc ion (65 Da, Ligand)
- 5.8s ribosomal rna (50 kDa, RNA from Candida albicans SC5314)
- Spermidine (145 Da, Ligand)
- Candida albicans 80s ribosome (3 MDa, Complex from Candida albicans SC5314)
- Ribosomal 40s subunit protein s18b (17 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l19 (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l28 (16 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l34b (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s9b (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l15 (24 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l5 (34 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l17b (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s2 (26 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s22-b (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l43a (10 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l26b (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s21 (9 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s5 (25 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l2a (27 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s30 (7 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l27 (15 kDa, Protein from Candida albicans SC5314)
- 5s ribosomal rna (38 kDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l22b (14 kDa, Protein from Candida albicans SC5314)
- 18s ribosomal rna (575 kDa, RNA from Candida albicans SC5314)
- Ribosomal 40s subunit protein s17b (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l32 (14 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s7 (21 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l11b (19 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l8 (28 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l24a (17 kDa, Protein from Candida albicans SC5314)
- Habp4_pai-rbp1 domain-containing protein (29 kDa, Protein from Candida albicans SC5314)
- 25s ribosomal rna (1 MDa, RNA from Candida albicans SC5314)
- Mixture of endogenous e-trna (24 kDa, RNA from Candida albicans SC5314)
- Ribosomal 60s subunit protein l42a (12 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s13 (16 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l13 (23 kDa, Protein from Candida albicans SC5314)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l20 (20 kDa, Protein from Candida albicans SC5314)
- 60s ribosomal protein l39 (6 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s8 (22 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s4 (29 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l3 (44 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l4b (39 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s26 (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal protein l37 (10 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s16a (15 kDa, Protein from Candida albicans SC5314)
- 40s ribosomal protein s24 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l25 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s20 (13 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l23b (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l30 (11 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l14b (14 kDa, Protein from Candida albicans SC5314)
- Ribosomal 40s subunit protein s15 (15 kDa, Protein from Candida albicans SC5314)
- Ribosomal 60s subunit protein l31b (12 kDa, Protein from Candida albicans SC5314)