Structure of Candida albicans 80S ribosome in complex with mefloquine
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8ogj
Q-score: 0.366
Kolosova O, Zgadzay Y, Yusupov M
To Be Published
- 40s ribosomal protein s27 (8 kDa, Protein from Candida albicans)
- 60s ribosomal protein l11-b (19 kDa, Protein from Candida albicans)
- 40s ribosomal protein s6 (27 kDa, Protein from Candida albicans)
- 40s ribosomal protein s18-b (17 kDa, Protein from Candida albicans)
- 60s ribosomal protein l38 (8 kDa, Protein from Candida albicans)
- 40s ribosomal protein s1 (29 kDa, Protein from Candida albicans)
- Candida albicans 80s ribosome in complex with mefloquine (3 MDa, Complex from Candida albicans)
- 60s ribosomal protein l2-b (27 kDa, Protein from Candida albicans)
- Ribosomal protein s23 (s12) (16 kDa, Protein from Candida albicans)
- 40s ribosomal protein s10-a (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s0 (28 kDa, Protein from Candida albicans)
- 60s ribosomal protein l13 (23 kDa, Protein from Candida albicans)
- 60s ribosomal protein l41 (3 kDa, Protein from Candida albicans)
- Mixture of endogenous e-trnas (24 kDa, RNA from Candida albicans)
- 40s ribosomal protein s24 (15 kDa, Protein from Candida albicans)
- 60s ribosomal protein l24-a (17 kDa, Protein from Candida albicans)
- 40s ribosomal protein s25 (11 kDa, Protein from Candida albicans)
- 60s ribosomal protein l28 (16 kDa, Protein from Candida albicans)
- Zinc ion (65 Da, Ligand)
- 18s ribosomal rna (575 kDa, RNA from Candida albicans)
- 60s ribosomal protein l42-b (12 kDa, Protein from Candida albicans)
- 40s ribosomal protein s28-b (7 kDa, Protein from Candida albicans)
- 60s ribosomal protein l3 (44 kDa, Protein from Candida albicans)
- 60s ribosomal protein l29 (7 kDa, Protein from Candida albicans)
- 60s ribosomal protein l9-b (21 kDa, Protein from Candida albicans)
- Spermine (fully protonated form) (206 Da, Ligand)
- 60s ribosomal protein l14-b (14 kDa, Protein from Candida albicans)
- 40s ribosomal protein s8 (22 kDa, Protein from Candida albicans)
- 60s ribosomal protein l23-a (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l39 (6 kDa, Protein from Candida albicans)
- 60s ribosomal protein l36 (11 kDa, Protein from Candida albicans)
- (11r,12s)- mefloquine (378 Da, Ligand)
- 60s ribosomal protein l34-b (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s30 (7 kDa, Protein from Candida albicans)
- 60s ribosomal protein l27 (15 kDa, Protein from Candida albicans)
- 40s ribosomal protein s22-a (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l6 (19 kDa, Protein from Candida albicans)
- 60s ribosomal protein l37-b (10 kDa, Protein from Candida albicans)
- Ribosomal protein l29 (14 kDa, Protein from Candida albicans)
- 40s ribosomal protein s11a (17 kDa, Protein from Candida albicans)
- 40s ribosomal protein s21 (9 kDa, Protein from Candida albicans)
- 5s ribosomal rna (38 kDa, RNA from Candida albicans)
- 25s ribosomal rna (1 MDa, RNA from Candida albicans)
- 40s ribosomal protein s12 (15 kDa, Protein from Candida albicans)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Candida albicans)
- 40s ribosomal protein s14-a (14 kDa, Protein from Candida albicans)
- Ubiquitin-40s ribosomal protein s31 fusion protein (22 kDa, Protein from Candida albicans)
- 60s ribosomal protein l20 (20 kDa, Protein from Candida albicans)
- 60s ribosomal protein l33-a (12 kDa, Protein from Candida albicans)
- 60s ribosomal protein l5 (34 kDa, Protein from Candida albicans)
- 60s ribosomal protein l25 (15 kDa, Protein from Candida albicans)
- Ribosomal protein s5 (26 kDa, Protein from Candida albicans)
- 40s ribosomal protein s16 (15 kDa, Protein from Candida albicans)
- 60s ribosomal protein l7-a (27 kDa, Protein from Candida albicans)
- 40s ribosomal protein s7 (21 kDa, Protein from Candida albicans)
- Ribosomal protein s4 (21 kDa, Protein from Candida albicans)
- Ribosomal protein l24 (14 kDa, Protein from Candida albicans)
- 40s ribosomal protein s19-a (16 kDa, Protein from Candida albicans)
- Ribosomal protein s7 (25 kDa, Protein from Candida albicans)
- Magnesium ion (24 Da, Ligand)
- 40s ribosomal protein s29a (6 kDa, Protein from Candida albicans)
- 60s ribosomal protein l19-a (21 kDa, Protein from Candida albicans)
- Ribosomal protein s3 (27 kDa, Protein from Candida albicans)
- 60s ribosomal protein l31-b (12 kDa, Protein from Candida albicans)
- 60s ribosomal protein l15-a (24 kDa, Protein from Candida albicans)
- 60s ribosomal protein l21-a (18 kDa, Protein from Candida albicans)
- Ribosomal protein l22 (21 kDa, Protein from Candida albicans)
- 40s ribosomal protein s13 (16 kDa, Protein from Candida albicans)
- 60s ribosomal protein l18-a (20 kDa, Protein from Candida albicans)
- 60s ribosomal protein l32 (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l4-b (39 kDa, Protein from Candida albicans)
- 60s ribosomal protein l22-b (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l40-b (6 kDa, Protein from Candida albicans)
- 60s ribosomal protein l10 (25 kDa, Protein from Candida albicans)
- 60s ribosomal protein l43-a (10 kDa, Protein from Candida albicans)
- Ribosomal protein s10 (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s26 (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s4 (29 kDa, Protein from Candida albicans)
- Ribosomal protein l13 (22 kDa, Protein from Candida albicans)
- 40s ribosomal protein s15 (15 kDa, Protein from Candida albicans)
- 40s ribosomal protein s17-b (15 kDa, Protein from Candida albicans)
- 5.8s ribosomal rna (50 kDa, RNA from Candida albicans)
- 60s ribosomal protein l8 (28 kDa, Protein from Candida albicans)
- 60s ribosomal protein l30 (11 kDa, Protein from Candida albicans)
Anton L, Cheng W, Haile M, Cobb DW, Zhu X, Han L, Li E, Nair A, Lee CL, Ho CM
To Be Published
- 60s ribosomal protein l13, putative (23 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l3 (44 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l17, putative (19 kDa, Protein from Plasmodium falciparum 3D7)
- Large ribosomal subunit protein el43 (10 kDa, Protein from Plasmodium falciparum 3D7)
- Plasmodium falciparum 80s ribosome consensus structure (Complex from Plasmodium falciparum 3D7)
- 40s ribosomal protein s8 (25 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l13 (25 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s26 (12 kDa, Protein from Plasmodium falciparum 3D7)
- Large ribosomal subunit protein el42 (12 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l11a, putative (20 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l7a (32 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s27 (9 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s19 (19 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s20e, putative (13 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s7 (22 kDa, Protein from Plasmodium falciparum 3D7)
- 5.8s ribosomal rna (51 kDa, RNA from Plasmodium falciparum 3D7)
- 60s ribosomal protein l7, putative (30 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l31 (14 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s3a (30 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l32 (15 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l6, putative (25 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s24 (15 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s23, putative (16 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l28 (14 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s25 (11 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l35ae, putative (16 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l19 (21 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s15a, putative (14 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s11 (16 kDa, Protein from Plasmodium falciparum 3D7)
- 28s ribosomal rna (1 MDa, RNA from Plasmodium falciparum 3D7)
- 60s ribosomal protein l29 (8 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s3 (24 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l18a (21 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l23 (22 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l10, putative (25 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s5, putative (21 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s4 (29 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s21 (9 kDa, Protein from Plasmodium falciparum 3D7)
- Ribosomal protein l37 (10 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s16 (16 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l34 (17 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l41 (6 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l39 (6 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l35, putative (14 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l14, putative (19 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l27 (16 kDa, Protein from Plasmodium falciparum 3D7)
- Receptor for activated c kinase (35 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l36 (12 kDa, Protein from Plasmodium falciparum 3D7)
- 18s ribosomal rna (669 kDa, RNA from Plasmodium falciparum 3D7)
- 60s ribosomal protein l26, putative (14 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l5, putative (34 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s19 (16 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l38 (10 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s11, putative (18 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s9, putative (22 kDa, Protein from Plasmodium falciparum 3D7)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l24, putative (23 kDa, RNA from Plasmodium falciparum 3D7)
- 60s ribosomal protein l27a, putative (16 kDa, Protein from Plasmodium falciparum 3D7)
- Ribosomal protein l15 (23 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l22, putative (16 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l18-2, putative (21 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l2 (28 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s10, putative (16 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l23, putative (15 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s5 (30 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s12 (15 kDa, Protein from Plasmodium falciparum 3D7)
- 5s ribosomal rna (38 kDa, RNA from Plasmodium falciparum 3D7)
- 40s ribosomal protein s6 (35 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l24, putative (19 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l30e, putative (11 kDa, Protein from Plasmodium falciparum 3D7)
- Small ribosomal subunit protein es30 (4 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s18, putative (17 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l21 (18 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s29, putative (6 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l6, putative (21 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l41 (5 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s17, putative (16 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein sa (29 kDa, Protein from Plasmodium falciparum 3D7)
- 60s ribosomal protein l4 (46 kDa, Protein from Plasmodium falciparum 3D7)
- 40s ribosomal protein s15 (17 kDa, Protein from Plasmodium falciparum 3D7)
EIF6-bound large subunit of the human ribosome
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7ow7
Q-score: 0.539
To Be Published
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 5.8s ribosomal rna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- Bromide ion (79 Da, Ligand)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- 60s ribosomal protein l39 (18 kDa, Protein from Homo sapiens)
- Human large ribosomal subunit (Complex from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10-like (24 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 isoform a (48 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 5lzs
Q-score: 0.462
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS
Cell (2016) 167 pp. 1229-1240.e15 [ Pubmed: 27863242 DOI: doi:10.1016/j.cell.2016.10.046 ]
- El40 (11 kDa, Protein from Oryctolagus cuniculus)
- Ul2 (28 kDa, Protein from Oryctolagus cuniculus)
- Es10 (18 kDa, Protein from Oryctolagus cuniculus)
- 18s ribosomal rna (602 kDa, RNA from Oryctolagus cuniculus)
- Ul24 (17 kDa, Protein from Oryctolagus cuniculus)
- Ul29 (14 kDa, Protein from Oryctolagus cuniculus)
- El22 (14 kDa, Protein from Oryctolagus cuniculus)
- El30 (12 kDa, Protein from Oryctolagus cuniculus)
- El20 (20 kDa, Protein from Oryctolagus cuniculus)
- Ul30 (29 kDa, Protein from Oryctolagus cuniculus)
- Us4 (26 kDa, Protein from Oryctolagus cuniculus)
- El14 (23 kDa, Protein from Oryctolagus cuniculus)
- Ul11 (17 kDa, Protein from Oryctolagus cuniculus)
- Us10 (13 kDa, Protein from Oryctolagus cuniculus)
- El32 (15 kDa, Protein from Oryctolagus cuniculus)
- Ul5 (20 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s6 (28 kDa, Protein from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Oryctolagus cuniculus)
- Us13 (17 kDa, Protein from Oryctolagus cuniculus)
- El21 (18 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- Affinity-purified 80s ribosome-nascent chain complex stalled with didemnin b and containing aminoacyl-trna and eef1a. (3 MDa, Complex from Oryctolagus cuniculus)
- Us19 (17 kDa, Protein from Oryctolagus cuniculus)
- Ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- El39 (6 kDa, Protein from Oryctolagus cuniculus)
- El19 (23 kDa, Protein from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- El28 (15 kDa, Protein from Oryctolagus cuniculus)
- Es30 (14 kDa, Protein from Oryctolagus cuniculus)
- El8 (36 kDa, Protein from Oryctolagus cuniculus)
- 28s ribosomal rna (1 MDa, RNA from Oryctolagus cuniculus)
- 40s ribosomal protein s8 (24 kDa, Protein from Oryctolagus cuniculus)
- 5s ribosomal rna (38 kDa, RNA from Oryctolagus cuniculus)
- El13 (24 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l10 (predicted) (24 kDa, Protein from Oryctolagus cuniculus)
- El42 (12 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- Es28 (7 kDa, Protein from Oryctolagus cuniculus)
- Ul3 (46 kDa, Protein from Oryctolagus cuniculus)
- Us11 (18 kDa, Protein from Oryctolagus cuniculus)
- El29 (26 kDa, Protein from Oryctolagus cuniculus)
- Elongation factor 1-alpha 1 (50 kDa, Protein from Oryctolagus cuniculus)
- El43 (10 kDa, Protein from Oryctolagus cuniculus)
- Uncharacterized protein (22 kDa, Protein from Oryctolagus cuniculus)
- Ul10 (34 kDa, Protein from Oryctolagus cuniculus)
- Es25 (13 kDa, Protein from Oryctolagus cuniculus)
- E-site trna (24 kDa, RNA from Oryctolagus cuniculus)
- Mrna (3 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
- Ul6 (21 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3a (30 kDa, Protein from Oryctolagus cuniculus)
- Us15 (17 kDa, Protein from Oryctolagus cuniculus)
- Es21 (9 kDa, Protein from Oryctolagus cuniculus)
- Ul24 (17 kDa, Protein from Oryctolagus cuniculus)
- Ul23 (17 kDa, Protein from Oryctolagus cuniculus)
- Us5 (31 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Us17 (18 kDa, Protein from Oryctolagus cuniculus)
- Us12 (15 kDa, Protein from Oryctolagus cuniculus)
- (2~{s})-~{n}-[(2~{r})-1-[[(3~{s},6~{s},8~{s},12~{s},13~{r},16~{s},17~{r},20~{s},23~{s})-13-[(2~{s})-butan-2-yl]-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-12-oxidanyl-2,5,7,10,15,19,22-heptakis(oxidanylidene)-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-~{n}-methyl-1-[(2~{s})-2-oxidanylpropanoyl]pyrrolidine-2-carboxamide (1 kDa, Ligand)
- Rack1 (35 kDa, Protein from Oryctolagus cuniculus)
- Us14 (6 kDa, Protein from Oryctolagus cuniculus)
- Us7 (22 kDa, Protein from Oryctolagus cuniculus)
- Es26 (13 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s9 (predicted) (22 kDa, Protein from Oryctolagus cuniculus)
- 5.8s ribosomal rna (50 kDa, RNA from Oryctolagus cuniculus)
- Us9 (16 kDa, Protein from Oryctolagus cuniculus)
- Ul14 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- Ul22 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l5 (34 kDa, Protein from Oryctolagus cuniculus)
- El18 (21 kDa, Protein from Oryctolagus cuniculus)
- El34 (13 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
- El31 (14 kDa, Protein from Oryctolagus cuniculus)
- Es17 (15 kDa, Protein from Oryctolagus cuniculus)
- Ul4 (47 kDa, Protein from Oryctolagus cuniculus)
- Trna (24 kDa, RNA from Oryctolagus cuniculus)
- Es19 (16 kDa, Protein from Oryctolagus cuniculus)
- Us2 (32 kDa, Protein from Oryctolagus cuniculus)
- Es31 (18 kDa, Protein from Oryctolagus cuniculus)
- Us8 (14 kDa, Protein from Oryctolagus cuniculus)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- El38 (8 kDa, Protein from Oryctolagus cuniculus)
- Ul15 (16 kDa, Protein from Oryctolagus cuniculus)
- Es24 (15 kDa, Protein from Oryctolagus cuniculus)
Structure of the mammalian ribosomal termination complex with eRF1 and eRF3.
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 5lzt
Q-score: 0.434
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS
Cell (2016) 167 pp. 1229-1240.e15 [ Pubmed: 27863242 DOI: doi:10.1016/j.cell.2016.10.046 ]
- El41 (3 kDa, Protein from Oryctolagus cuniculus)
- 18s ribosomal rna (602 kDa, RNA from Oryctolagus cuniculus)
- El40 (11 kDa, Protein from Oryctolagus cuniculus)
- Ul2 (28 kDa, Protein from Oryctolagus cuniculus)
- El15 (24 kDa, Protein from Oryctolagus cuniculus)
- Es10 (18 kDa, Protein from Oryctolagus cuniculus)
- Ul24 (17 kDa, Protein from Oryctolagus cuniculus)
- Ul29 (14 kDa, Protein from Oryctolagus cuniculus)
- El22 (14 kDa, Protein from Oryctolagus cuniculus)
- El30 (12 kDa, Protein from Oryctolagus cuniculus)
- El20 (20 kDa, Protein from Oryctolagus cuniculus)
- Ul30 (29 kDa, Protein from Oryctolagus cuniculus)
- Es8 (24 kDa, Protein from Oryctolagus cuniculus)
- El14 (23 kDa, Protein from Oryctolagus cuniculus)
- Ul11 (17 kDa, Protein from Oryctolagus cuniculus)
- Us10 (13 kDa, Protein from Oryctolagus cuniculus)
- Es6 (28 kDa, Protein from Oryctolagus cuniculus)
- El32 (15 kDa, Protein from Oryctolagus cuniculus)
- Ul5 (20 kDa, Protein from Oryctolagus cuniculus)
- El37 (11 kDa, Protein from Oryctolagus cuniculus)
- Us7 (22 kDa, Protein from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Oryctolagus cuniculus)
- Es1 (30 kDa, Protein from Oryctolagus cuniculus)
- Us13 (17 kDa, Protein from Oryctolagus cuniculus)
- El21 (18 kDa, Protein from Oryctolagus cuniculus)
- Us19 (17 kDa, Protein from Oryctolagus cuniculus)
- Ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- El39 (6 kDa, Protein from Oryctolagus cuniculus)
- El19 (23 kDa, Protein from Oryctolagus cuniculus)
- Nascent chain (1 kDa, Protein from Oryctolagus cuniculus)
- Mrna (uga stop codon) (4 kDa, RNA from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- El6 (33 kDa, Protein from Oryctolagus cuniculus)
- El28 (15 kDa, Protein from Oryctolagus cuniculus)
- Es30 (14 kDa, Protein from Oryctolagus cuniculus)
- El8 (36 kDa, Protein from Oryctolagus cuniculus)
- 28s ribosomal rna (1 MDa, RNA from Oryctolagus cuniculus)
- Erf3a (68 kDa, Protein from Homo sapiens)
- El24 (17 kDa, Protein from Oryctolagus cuniculus)
- Ul16 (24 kDa, Protein from Oryctolagus cuniculus)
- El27 (15 kDa, Protein from Oryctolagus cuniculus)
- 5s ribosomal rna (38 kDa, RNA from Oryctolagus cuniculus)
- Ul18 (34 kDa, Protein from Oryctolagus cuniculus)
- El13 (24 kDa, Protein from Oryctolagus cuniculus)
- El42 (12 kDa, Protein from Oryctolagus cuniculus)
- Es4 (29 kDa, Protein from Oryctolagus cuniculus)
- Es28 (7 kDa, Protein from Oryctolagus cuniculus)
- Ul3 (46 kDa, Protein from Oryctolagus cuniculus)
- Affinity-purified 80s ribosome-nascent chain complex reconstituted with erf1 and erf3. (3 MDa, Complex from Oryctolagus cuniculus)
- Us11 (18 kDa, Protein from Oryctolagus cuniculus)
- El29 (26 kDa, Protein from Oryctolagus cuniculus)
- Es27 (9 kDa, Protein from Oryctolagus cuniculus)
- El43 (10 kDa, Protein from Oryctolagus cuniculus)
- Es12 (14 kDa, Protein from Oryctolagus cuniculus)
- Ul10 (34 kDa, Protein from Oryctolagus cuniculus)
- Us4 (22 kDa, Protein from Oryctolagus cuniculus)
- Es25 (13 kDa, Protein from Oryctolagus cuniculus)
- E-site trna (24 kDa, RNA from Oryctolagus cuniculus)
- El34 (13 kDa, Protein from Oryctolagus cuniculus)
- Ul6 (21 kDa, Protein from Oryctolagus cuniculus)
- Us15 (17 kDa, Protein from Oryctolagus cuniculus)
- Es21 (9 kDa, Protein from Oryctolagus cuniculus)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Ul23 (17 kDa, Protein from Oryctolagus cuniculus)
- Us5 (31 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Us17 (18 kDa, Protein from Oryctolagus cuniculus)
- Us12 (15 kDa, Protein from Oryctolagus cuniculus)
- Rack1 (35 kDa, Protein from Oryctolagus cuniculus)
- Us14 (6 kDa, Protein from Oryctolagus cuniculus)
- Es26 (13 kDa, Protein from Oryctolagus cuniculus)
- 5.8s ribosomal rna (50 kDa, RNA from Oryctolagus cuniculus)
- Us9 (16 kDa, Protein from Oryctolagus cuniculus)
- Ul14 (14 kDa, Protein from Oryctolagus cuniculus)
- Es7 (22 kDa, Protein from Oryctolagus cuniculus)
- Erf1 (51 kDa, Protein from Homo sapiens)
- Ul22 (21 kDa, Protein from Oryctolagus cuniculus)
- El36 (12 kDa, Protein from Oryctolagus cuniculus)
- P-site trna (24 kDa, RNA from Oryctolagus cuniculus)
- El18 (21 kDa, Protein from Oryctolagus cuniculus)
- El31 (14 kDa, Protein from Oryctolagus cuniculus)
- Es17 (15 kDa, Protein from Oryctolagus cuniculus)
- Ul4 (47 kDa, Protein from Oryctolagus cuniculus)
- Es19 (16 kDa, Protein from Oryctolagus cuniculus)
- Us2 (32 kDa, Protein from Oryctolagus cuniculus)
- Es31 (18 kDa, Protein from Oryctolagus cuniculus)
- Us3 (26 kDa, Protein from Oryctolagus cuniculus)
- Us8 (14 kDa, Protein from Oryctolagus cuniculus)
- El38 (8 kDa, Protein from Oryctolagus cuniculus)
- Ul15 (16 kDa, Protein from Oryctolagus cuniculus)
- Es24 (15 kDa, Protein from Oryctolagus cuniculus)
Structure of the mammalian ribosomal termination complex with accommodated eRF1
Resolution: 3.75 Å
EM Method: Single-particle
Fitted PDBs: 5lzu
Q-score: 0.399
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS
Cell (2016) 167 pp. 1229-1240.e15 [ Pubmed: 27863242 DOI: doi:10.1016/j.cell.2016.10.046 ]
- 18s ribosomal rna (602 kDa, RNA from Oryctolagus cuniculus)
- El40 (11 kDa, Protein from Oryctolagus cuniculus)
- Ul2 (28 kDa, Protein from Oryctolagus cuniculus)
- Es10 (18 kDa, Protein from Oryctolagus cuniculus)
- Ul24 (17 kDa, Protein from Oryctolagus cuniculus)
- Ul29 (14 kDa, Protein from Oryctolagus cuniculus)
- El22 (14 kDa, Protein from Oryctolagus cuniculus)
- El30 (12 kDa, Protein from Oryctolagus cuniculus)
- El20 (20 kDa, Protein from Oryctolagus cuniculus)
- Ul30 (29 kDa, Protein from Oryctolagus cuniculus)
- El14 (23 kDa, Protein from Oryctolagus cuniculus)
- Ul11 (17 kDa, Protein from Oryctolagus cuniculus)
- Us10 (13 kDa, Protein from Oryctolagus cuniculus)
- El32 (15 kDa, Protein from Oryctolagus cuniculus)
- Ul5 (20 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- Us7 (22 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s6 (28 kDa, Protein from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Oryctolagus cuniculus)
- Us13 (17 kDa, Protein from Oryctolagus cuniculus)
- El21 (18 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- Us19 (17 kDa, Protein from Oryctolagus cuniculus)
- Ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- El39 (6 kDa, Protein from Oryctolagus cuniculus)
- El19 (23 kDa, Protein from Oryctolagus cuniculus)
- Mrna (uga stop codon) (4 kDa, RNA from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- El28 (15 kDa, Protein from Oryctolagus cuniculus)
- Es30 (14 kDa, Protein from Oryctolagus cuniculus)
- El8 (36 kDa, Protein from Oryctolagus cuniculus)
- 28s ribosomal rna (1 MDa, RNA from Oryctolagus cuniculus)
- El24 (17 kDa, Protein from Oryctolagus cuniculus)
- Ul16 (24 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s8 (24 kDa, Protein from Oryctolagus cuniculus)
- 5s ribosomal rna (38 kDa, RNA from Oryctolagus cuniculus)
- El13 (24 kDa, Protein from Oryctolagus cuniculus)
- El42 (12 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- Es28 (7 kDa, Protein from Oryctolagus cuniculus)
- Ul3 (46 kDa, Protein from Oryctolagus cuniculus)
- Us11 (18 kDa, Protein from Oryctolagus cuniculus)
- El29 (26 kDa, Protein from Oryctolagus cuniculus)
- El43 (10 kDa, Protein from Oryctolagus cuniculus)
- Affinity-purified 80s ribosome-nascent chain complex reconstituted with erf1. (3 MDa, Complex from Oryctolagus cuniculus)
- Ul10 (34 kDa, Protein from Oryctolagus cuniculus)
- Es25 (13 kDa, Protein from Oryctolagus cuniculus)
- E-site trna (24 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
- El34 (13 kDa, Protein from Oryctolagus cuniculus)
- Eukaryotic peptide chain release factor subunit 1 (51 kDa, Protein from Homo sapiens)
- Ul6 (21 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3a (30 kDa, Protein from Oryctolagus cuniculus)
- Us15 (17 kDa, Protein from Oryctolagus cuniculus)
- Es21 (9 kDa, Protein from Oryctolagus cuniculus)
- Ul23 (17 kDa, Protein from Oryctolagus cuniculus)
- Us5 (31 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Us17 (18 kDa, Protein from Oryctolagus cuniculus)
- Us12 (15 kDa, Protein from Oryctolagus cuniculus)
- Rack1 (35 kDa, Protein from Oryctolagus cuniculus)
- Us14 (6 kDa, Protein from Oryctolagus cuniculus)
- Es26 (13 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s9 (predicted) (22 kDa, Protein from Oryctolagus cuniculus)
- 5.8s ribosomal rna (50 kDa, RNA from Oryctolagus cuniculus)
- Us9 (16 kDa, Protein from Oryctolagus cuniculus)
- Ul14 (14 kDa, Protein from Oryctolagus cuniculus)
- Es7 (22 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- Ul22 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l5 (34 kDa, Protein from Oryctolagus cuniculus)
- P-site trna (24 kDa, RNA from Oryctolagus cuniculus)
- El18 (21 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
- El31 (14 kDa, Protein from Oryctolagus cuniculus)
- Es17 (15 kDa, Protein from Oryctolagus cuniculus)
- Ul4 (47 kDa, Protein from Oryctolagus cuniculus)
- Es19 (16 kDa, Protein from Oryctolagus cuniculus)
- Us2 (32 kDa, Protein from Oryctolagus cuniculus)
- Es31 (18 kDa, Protein from Oryctolagus cuniculus)
- Us3 (26 kDa, Protein from Oryctolagus cuniculus)
- Us8 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- El38 (8 kDa, Protein from Oryctolagus cuniculus)
- Ul15 (16 kDa, Protein from Oryctolagus cuniculus)
- Es24 (15 kDa, Protein from Oryctolagus cuniculus)