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sample_name:"50S ribosomal protein L22" AND resolution:[2 TO 3} AND author_name:"Osterman IA"
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Escherichia coli 70S ribosome bound to thermorubin, deacylated P-site tRNAfMet and aminoacylated A-site Phe-tRNA

Release date: Dec. 7, 2022
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8ekc
Q-score: 0.553

Paranjpe MN, Marina VI, Grachev AA, Maviza TP, Tolicheva OA, Paleskava A, Osterman IA, Sergiev PV, Konevega AL, Polikanov YS, Gagnon MG

Nucleic Acids Res (2023) 51 pp. 449-462 [ Pubmed: 36546783 DOI: doi:10.1093/nar/gkac1189 ]

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70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B

Release date: May 18, 2022
Resolution: 2.58 Å
EM Method: Single-particle
Fitted PDBs: 7ug7
Q-score: 0.536

Wieland M, Holm M, Rundlet EJ, Morici M, Koller TO, Maviza TP, Pogorevc D, Osterman IA, Muller R, Blanchard SC, Wilson DN

PNAS (2022) 119 pp. e2114214119-e2114214119 [ DOI: doi:10.1073/pnas.2114214119 Pubmed: 35500116 ]

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Cryo-EM structure of an Escherichia coli 70S ribosome in complex with elongation factor G and the antibiotic Argyrin B

Release date: May 11, 2022
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7otc
Q-score: 0.504

Wieland M, Holm M, Rundlet EJ, Morici M, Koller TO, Maviza TP, Pogorevc D, Osterman IA, Muller R, Blanchard SC, Wilson DN

PNAS (2022) 119 pp. e2114214119-e2114214119 [ DOI: doi:10.1073/pnas.2114214119 Pubmed: 35500116 ]

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E. coli 70S ribosome in complex with dirithromycin, and deacylated tRNA(iMet) (focused classification).

Release date: Nov. 4, 2020
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 6xza
Q-score: 0.412

Pichkur EB, Paleskava A, Tereshchenkov AG, Kasatsky P, Komarova ES, Shiriaev DI, Bogdanov AA, Dontsova OA, Osterman IA, Sergiev PV, Polikanov YS, Myasnikov AG, Konevega AL

RNA (2020) 26 pp. 715-723 [ Pubmed: 32144191 DOI: doi:10.1261/rna.073817.119 ]

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E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet) (focused classification).

Release date: Nov. 4, 2020
Resolution: 2.54 Å
EM Method: Single-particle
Fitted PDBs: 6xzb
Q-score: 0.432

Pichkur EB, Paleskava A, Tereshchenkov AG, Kasatsky P, Komarova ES, Shiriaev DI, Bogdanov AA, Dontsova OA, Osterman IA, Sergiev PV, Polikanov YS, Myasnikov AG, Konevega AL

RNA (2020) 26 pp. 715-723 [ Pubmed: 32144191 DOI: doi:10.1261/rna.073817.119 ]

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E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).

Release date: July 22, 2020
Resolution: 2.1 Å
EM Method: Single-particle
Fitted PDBs: 6xz7
Q-score: 0.643

Pichkur EB, Paleskava A, Tereshchenkov AG, Kasatsky P, Komarova ES, Shiriaev DI, Bogdanov AA, Dontsova OA, Osterman IA, Sergiev PV, Polikanov YS, Myasnikov AG, Konevega AL

RNA (2020) 26 pp. 715-723 [ Pubmed: 32144191 DOI: doi:10.1261/rna.073817.119 ]

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Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX

Release date: July 1, 2020
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 6y69
Q-score: 0.486

Osterman IA, Wieland M, Maviza TP, Lashkevich KA, Lukianov DA, Komarova ES, Zakalyukina YV, Buschauer R, Shiriaev DI, Leyn SA, Zlamal JE, Biryukov MV, Skvortsov DA, Tashlitsky VN, Polshakov VI, Cheng J, Polikanov YS, Bogdanov AA, Osterman AL, Dmitriev SE, Beckmann R, Dontsova OA, Wilson DN, Sergiev PV

Nat Chem Biol (2020) 16 pp. 1071-1077 [ DOI: doi:10.1038/s41589-020-0578-x Pubmed: 32601485 ]

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