Cryo-EM structure of Mycobacterium tuberculosis 50S ribosome subunit bound with clarithromycin
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7f0d
Q-score: 0.473
Zhang W, Li Z, Sun Y, Cui P, Liang J, Xing Q, Wu J, Xu Y, Zhang W, Zhang Y, He L, Gao N
Emerg Microbes Infect (2022) 11 pp. 293-305 [ Pubmed: 34935599 DOI: doi:10.1080/22221751.2021.2022439 ]
- 50s ribosomal protein l35 (7 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l6 (19 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- Water (18 Da, Ligand)
- 50s ribosomal subunit (Complex from Mycobacterium tuberculosis H37Ra)
- Magnesium ion (24 Da, Ligand)
- Clarithromycin (747 Da, Ligand)
- 50s ribosomal protein l17 (19 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l19 (13 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l4 (23 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l32 (6 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l34 (5 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l3 (23 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l18 (13 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- Mycobacterium tuberculosis ribosome 50s subunit (Complex)
- 50s ribosomal protein l20 (14 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 5s ribosomal rna (37 kDa, RNA from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l15 (15 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l21 (11 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l36 (4 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l5 (21 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l28 (6 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l22 (20 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l31 (8 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l23 (10 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l2 (30 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l30 (7 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l27 (8 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l24 (11 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l29 (8 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l13 (16 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l14 (13 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l25 (22 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l9 (16 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l16 (15 kDa, Protein from Mycobacterium tuberculosis H37Ra)
- 23s rrna (1 MDa, RNA from Mycobacterium tuberculosis H37Ra)
- 50s ribosomal protein l33 (6 kDa, Protein from Mycobacterium tuberculosis H37Ra)