Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7zta
Q-score: 0.565
Leroy EC, Perry TN, Renault TT, Innis CA
Nat Chem Biol (2023) 19 pp. 1091-1096 [ DOI: doi:10.1038/s41589-023-01343-0 Pubmed: 37322159 ]
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l17 (13 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s3 (23 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal subunit (Complex from Escherichia coli K-12)
- 50s ribosomal protein l28 (8 kDa, Protein from Escherichia coli K-12)
- Trna-cys (23 kDa, RNA from Escherichia coli K-12)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s6, fully modified isoform (12 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli K-12)
- Glutamine (146 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s5 (16 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli K-12)
- Mrna (Complex from Escherichia coli K-12)
- Structure of an escherichia coli 70s ribosome stalled by tetracenomycin x during translation of an maaapqk(c) peptide (Complex from Escherichia coli K-12)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli K-12)
- Maaapqk nascent peptide (716 Da, Protein from Escherichia coli K-12)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli K-12)
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal subunit (Complex from Escherichia coli K-12)
- 16s ribosomal rna (497 kDa, RNA from Escherichia coli K-12)
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s19 (9 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s7 (16 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli K-12)
- Mrna (4 kDa, RNA from Escherichia coli K-12)
- Water (18 Da, Ligand)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s11 (12 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s18 (7 kDa, Protein from Escherichia coli K-12)
- Cysteine (121 Da, Ligand)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli K-12)
- Tetracenomycin x (486 Da, Ligand)
- Trna-lys (24 kDa, RNA from Escherichia coli K-12)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s13 (12 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s2 (24 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli K-12)
- Trna-gln (24 kDa, RNA from Escherichia coli K-12)
- 30s ribosomal protein s21 (6 kDa, Protein from Escherichia coli K-12)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli K-12)
- Magnesium ion (24 Da, Ligand)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli K-12)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli K-12)
- Maaapqk-trna-lys (p site) (Complex)
- 50s ribosomal protein l33 (5 kDa, Protein from Escherichia coli K-12)
- Trna-cys (a site) (Complex from Escherichia coli K-12)
- Trna-gln (e site) (Complex from Escherichia coli K-12)
- 50s ribosomal protein l23 (10 kDa, Protein from Escherichia coli K-12)
Majumdar C, Walker JA, Francis MB, Schepartz A, Cate JHD
ACS Cent Sci (2023) 9 pp. 1160-1169 [ DOI: doi:10.1021/acscentsci.3c00153 Pubmed: 37396857 ]
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli)
- 70s e.coli ribosome (Complex from Escherichia coli)
- 30s ribosomal protein s3 (26 kDa, Protein from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli)
- Spermidine (145 Da, Ligand)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- Mrna (9 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s6 (15 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli)
- A-site oabz-trnaphe (24 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s2 (26 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- Paromomycin (615 Da, Ligand)
- 30s ribosomal protein s11 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli)
- 2-amino-benzamide (136 Da, Ligand)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 16s rrna (499 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s5 (17 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- 30s ribosomal protein s19 (10 kDa, Protein from Escherichia coli)
- N-formylmethionine (177 Da, Ligand)
- Ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate) (346 Da, Ligand)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- Water (18 Da, Ligand)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s18 (9 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s21 (8 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s13 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli)
- P-site fmet-trnafmet (24 kDa, RNA from Escherichia coli)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
Resolution: 2.09 Å
EM Method: Single-particle
Fitted PDBs: 8g6y
Q-score: 0.724
Majumdar C, Walker JA, Francis MB, Schepartz A, Cate JHD
ACS Cent Sci (2023) 9 pp. 1160-1169 [ DOI: doi:10.1021/acscentsci.3c00153 Pubmed: 37396857 ]
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- A-site trna phe (24 kDa, RNA from Escherichia coli)
- Mrna (9 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- P-site trna fmet (24 kDa, RNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
- 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate) (346 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli)
- N-formylmethionine (177 Da, Ligand)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- Water (18 Da, Ligand)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 3-aminopyridine-4-carboxamide (137 Da, Ligand)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s subunit of e.coli ribosome (Complex from Escherichia coli)
Cutibacterium acnes 70S ribosome with mRNA, P-site tRNA and Sarecycline bound
Resolution: 2.78 Å
EM Method: Single-particle
Fitted PDBs: 8crx
Q-score: 0.519
Lomakin IB, Devarkar SC, Patel S, Grada A, Bunick CG
Nucleic Acids Res (2023) 51 pp. 2915-2930 [ Pubmed: 36864821 DOI: doi:10.1093/nar/gkad103 ]
- 50s ribosomal protein l6 (19 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s16 (15 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l3 (23 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s4 (23 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l20 (13 kDa, Protein from Cutibacterium acnes)
- P-site initiator trna (24 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s5 (22 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s20 (9 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l5 (23 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l4 (32 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s10 (11 kDa, Protein from Cutibacterium acnes)
- 70s ribosome with mrna, p-site trna and sarecycline bound (Complex from Cutibacterium acnes)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l15 (15 kDa, Protein from Cutibacterium acnes)
- 5s ribosomal rna (38 kDa, RNA from Cutibacterium acnes)
- 50s ribosomal protein l18 (13 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s12 (13 kDa, Protein from Cutibacterium acnes)
- Rna (1537-mer) (498 kDa, RNA from Cutibacterium acnes)
- 30s ribosomal protein s11 (14 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s6 (11 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l23 (11 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l27 (9 kDa, Protein from Cutibacterium acnes)
- 32mf mrna (7 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l28 (6 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s9 (18 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein bs22 (4 kDa, Protein from Cutibacterium acnes)
- Water (18 Da, Ligand)
- 50s ribosomal protein l34 (5 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l14 (13 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l35 (7 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l22 (16 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l19 (13 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s13 (14 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s19 (10 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l36 (4 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s17 (10 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l25 (22 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s18 (8 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l29 (8 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l30 (6 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l33 (6 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s14 type z (6 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s15 (10 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l16 (15 kDa, Protein from Cutibacterium acnes)
- 23s ribosomal rna (1 MDa, RNA from Cutibacterium acnes)
- 50s ribosomal protein l13 (16 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l32 (6 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l17 (20 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l21 (11 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s3 (29 kDa, Protein from Cutibacterium acnes)
- 30s ribosomal protein s2 (31 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l2 (30 kDa, Protein from Cutibacterium acnes)
- Magnesium ion (24 Da, Ligand)
- 30s ribosomal protein s7 (17 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l31 (7 kDa, Protein from Cutibacterium acnes)
- Sarecycline (487 Da, Ligand)
- 30s ribosomal protein s8 (14 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l24 (13 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein bl37 (2 kDa, Protein from Cutibacterium acnes)
Resolution: 2.31 Å
EM Method: Single-particle
Fitted PDBs: 8g6x
Q-score: 0.693
Majumdar C, Walker JA, Francis MB, Schepartz A, Cate JHD
ACS Cent Sci (2023) 9 pp. 1160-1169 [ DOI: doi:10.1021/acscentsci.3c00153 Pubmed: 37396857 ]
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli)
- Spermidine (145 Da, Ligand)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- A-site trna phe (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- Mrna (9 kDa, RNA from Escherichia coli)
- P-site trna fmet (24 kDa, RNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 3-aminobenzamide (136 Da, Ligand)
- Spermine (202 Da, Ligand)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
- 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate) (346 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli)
- N-formylmethionine (177 Da, Ligand)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- Water (18 Da, Ligand)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- 50s subunit of e.coli ribosome (Complex from Escherichia coli)
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8cvm
Q-score: 0.565
Lomakin IB, Devarkar SC, Patel S, Grada A, Bunick CG
Nucleic Acids Res (2023) 51 pp. 2915-2930 [ Pubmed: 36864821 DOI: doi:10.1093/nar/gkad103 ]
- 50s ribosomal protein l6 (19 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l3 (23 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l20 (13 kDa, Protein from Cutibacterium acnes)
- 50s subunit from 70s ribosome with mrna, p-site trna and sarecycline bound (Complex from Cutibacterium acnes)
- 50s ribosomal protein l5 (23 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l4 (32 kDa, Protein from Cutibacterium acnes)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l15 (15 kDa, Protein from Cutibacterium acnes)
- 5s ribosomal rna (38 kDa, RNA from Cutibacterium acnes)
- 50s ribosomal protein l18 (13 kDa, Protein from Cutibacterium acnes)
- Initiator fmet rna (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l27 (9 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l28 (6 kDa, Protein from Cutibacterium acnes)
- Water (18 Da, Ligand)
- 50s ribosomal protein l34 (5 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l14 (13 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l35 (7 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l22 (16 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l19 (13 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l36 (4 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l25 (22 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l29 (8 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l30 (6 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l33 (6 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l16 (15 kDa, Protein from Cutibacterium acnes)
- 23s ribosomal rna (1 MDa, RNA from Cutibacterium acnes)
- 50s ribosomal protein l13 (16 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l32 (6 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l17 (20 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l21 (11 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein l2 (30 kDa, Protein from Cutibacterium acnes)
- Magnesium ion (24 Da, Ligand)
- 50s ribosomal protein l31 (7 kDa, Protein from Cutibacterium acnes)
- Sarecycline (487 Da, Ligand)
- 50s ribosomal protein l24 (13 kDa, Protein from Cutibacterium acnes)
- 50s ribosomal protein bl37 (2 kDa, Protein from Cutibacterium acnes)
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 8akn
Q-score: 0.647
Koller TO, Morici M, Berger M, Safdari HA, Lele DS, Beckert B, Kaur KJ, Wilson DN
Nat Chem Biol (2023) 19 pp. 1072-1081 [ Pubmed: 36997646 DOI: doi:10.1038/s41589-023-01293-7 ]
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s13 (13 kDa, Protein from Escherichia coli BW25113)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli BW25113)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli BW25113)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli BW25113)
- Isoleucine-trna (24 kDa, RNA from Escherichia coli BW25113)
- 30s ribosomal protein s2 (26 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli BW25113)
- Spermine (202 Da, Ligand)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s5 (17 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli BW25113)
- Cryo-em structure of the proline-rich antimicrobial peptide drosocin bound to the terminating ribosome (2 MDa, Complex from Escherichia coli BW25113)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s21 (8 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s18 (9 kDa, Protein from Escherichia coli BW25113)
- Mrna (2 kDa, RNA from Escherichia coli BW25113)
- Peptide chain release factor rf1 (40 kDa, Protein from Escherichia coli BW25113)
- 2-acetamido-2-deoxy-alpha-d-galactopyranose (221 Da, Ligand)
- Water (18 Da, Ligand)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s11 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s6, fully modified isoform (15 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s3 (26 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli BW25113)
- Phenylalanine-trna (24 kDa, RNA from Escherichia coli BW25113)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli BW25113)
- 16s ribosomal rna (497 kDa, RNA from Escherichia coli BW25113)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s19 (10 kDa, Protein from Escherichia coli BW25113)
- Drosocin1 (2 kDa, Protein from Drosophila melanogaster)
- Magnesium ion (24 Da, Ligand)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli BW25113)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli BW25113)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8am9
Q-score: 0.594
Koller TO, Morici M, Berger M, Safdari HA, Lele DS, Beckert B, Kaur KJ, Wilson DN
Nat Chem Biol (2023) 19 pp. 1072-1081 [ Pubmed: 36997646 DOI: doi:10.1038/s41589-023-01293-7 ]
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli BW25113)
- Cryo-em structure of the proline-rich antimicrobial peptide drosocin bound to the elongating ribosome (2 MDa, Complex from Escherichia coli K-12)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s13 (13 kDa, Protein from Escherichia coli BW25113)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli BW25113)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli BW25113)
- 16s ribosomal rna (497 kDa, RNA from Escherichia coli BW25113)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli BW25113)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s2 (26 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli BW25113)
- Mrna (3 kDa, RNA from Escherichia coli BW25113)
- Spermine (202 Da, Ligand)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s5 (17 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s21 (8 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s18 (9 kDa, Protein from Escherichia coli BW25113)
- Initiator trna (24 kDa, RNA from Escherichia coli BW25113)
- Leucine trna (27 kDa, RNA from Escherichia coli BW25113)
- 2-acetamido-2-deoxy-alpha-d-galactopyranose (221 Da, Ligand)
- Water (18 Da, Ligand)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s11 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s6, fully modified isoform (15 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s3 (26 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s19 (10 kDa, Protein from Escherichia coli BW25113)
- Drosocin1 (2 kDa, Protein from Drosophila melanogaster)
- Magnesium ion (24 Da, Ligand)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli BW25113)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli BW25113)
Resolution: 2.1 Å
EM Method: Single-particle
Fitted PDBs: 8ana
Q-score: 0.695
Koller TO, Morici M, Berger M, Safdari HA, Lele DS, Beckert B, Kaur KJ, Wilson DN
Nat Chem Biol (2023) 19 pp. 1072-1081 [ Pubmed: 36997646 DOI: doi:10.1038/s41589-023-01293-7 ]
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli BW25113)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli BW25113)
- Spermine (202 Da, Ligand)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli BW25113)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli BW25113)
- 2-acetamido-2-deoxy-alpha-d-galactopyranose (221 Da, Ligand)
- Water (18 Da, Ligand)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli BW25113)
- Cryo-em structure of the proline-rich antimicrobial peptide drosocin bound to the 50s ribosomal subunit (1 MDa, Complex from Escherichia coli K-12)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli BW25113)
- Drosocin1 (2 kDa, Protein from Drosophila melanogaster)
- Magnesium ion (24 Da, Ligand)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli BW25113)
E. coli 70S ribosome bound to thermorubin and fMet-tRNA
Resolution: 1.96 Å
EM Method: Single-particle
Fitted PDBs: 8aye
Q-score: 0.734
Parajuli NP, Emmerich A, Mandava CS, Pavlov MY, Sanyal S
Nat Commun (2023) 14 pp. 918-918 [ Pubmed: 36806263 DOI: doi:10.1038/s41467-023-36528-7 ]
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l31 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s21 (8 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s13 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- Mrna (1 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s19 (10 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s11 (13 kDa, Protein from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- 30s ribosomal protein s5 (17 kDa, Protein from Escherichia coli)
- E. coli 70s ribosome bound to thermorubin and fmet-trna (Complex from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli)
- P-site trna-fmet (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s6, fully modified isoform (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s3 (26 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s18 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s2 (26 kDa, Protein from Escherichia coli)
- E-site trna (589 Da, RNA from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- Thermorubin (600 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 16s rrna (499 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli)