Ternary complex of translating ribosome, NAC and METAP1
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8p2k
Q-score: 0.483
Gamerdinger M, Jia M, Schloemer R, Rabl L, Jaskolowski M, Khakzar KM, Ulusoy Z, Wallisch A, Jomaa A, Hunaeus G, Scaiola A, Diederichs K, Ban N, Deuerling E
Science (2023) 380 pp. 1238-1243 [ Pubmed: 37347872 DOI: doi:10.1126/science.adg3297 ]
- Transcription factor btf3 (14 kDa, Protein from Homo sapiens)
- Ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
- Ribosome translating a cytosolic peptide (Complex from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein sa (32 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s14 (16 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
- El42 (12 kDa, Protein from Oryctolagus cuniculus)
- 5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
- 5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
- Nascent polypeptide-associated complex subunit alpha (23 kDa, Protein from Homo sapiens)
- Ribosomal protein s15a (14 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein ul30 (29 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l12 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s30 (14 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein ul1 (24 kDa, Protein from Oryctolagus cuniculus)
- Us9 (19 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s6 (28 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l8 (28 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l30 (12 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s21 (9 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s18 (17 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s29 (6 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s9 (22 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l32 (15 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l22 (14 kDa, Protein from Oryctolagus cuniculus)
- Spermine (202 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Spermidine (145 Da, Ligand)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- 40s ribosomal protein s13 (17 kDa, Protein from Oryctolagus cuniculus)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Any 5'-monophosphate nucleotide (214 Da, Ligand)
- Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s8 (24 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s5 (22 kDa, Protein from Oryctolagus cuniculus)
- 60s acidic ribosomal protein p0 (34 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3 (31 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s25 (13 kDa, Protein from Oryctolagus cuniculus)
- S10_plectin domain-containing protein (18 kDa, Protein from Oryctolagus cuniculus)
- Glucose-6-phosphate isomerase (7 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s27a (18 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal_l23en domain-containing protein (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
- Unknown atom or ion (Ligand)
- 60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l39-like (6 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s2 (31 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein us19 (17 kDa, Protein from Oryctolagus cuniculus)
- Water (18 Da, Ligand)
- 40s ribosomal protein s11 (18 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l37a (10 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
- P-site val-trna (24 kDa, RNA from Oryctolagus cuniculus)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s23 (15 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l5 eukaryotic c-terminal domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
- Complex of nac and metap1 at the tennel exit of translating ribosome (Complex)
- Acetylamino-acetic acid (117 Da, Ligand)
- 40s ribosomal protein us10 (13 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3a (30 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Rack1 (35 kDa, Protein from Oryctolagus cuniculus)
- 18s rrna (603 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l13a (23 kDa, Protein from Oryctolagus cuniculus)
- Es26 (13 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l13 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l28 (15 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- Ul22 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (26 kDa, Protein from Oryctolagus cuniculus)
- El18 (21 kDa, Protein from Oryctolagus cuniculus)
- E-site trna (15 kDa, RNA from Oryctolagus cuniculus)
- 40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s19 (16 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
- Methionine aminopeptidase 1 (43 kDa, Protein from Homo sapiens)
- Ternary complex of translating ribosome, nac and metap1 (Complex from Oryctolagus cuniculus)
- 60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l7a (30 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s7 (47 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein es17 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s28 (7 kDa, Protein from Oryctolagus cuniculus)
Ternary complex of ribosome nascent chain with SRP and NAC
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7qwq
Q-score: 0.426
Jomaa A, Gamerdinger M, Hsieh HH, Wallisch A, Chandrasekaran V, Ulusoy Z, Scaiola A, Hegde RS, Shan SO, Ban N, Deuerling E
Science (2022) 375 pp. 839-844 [ DOI: doi:10.1126/science.abl6459 Pubmed: 35201867 ]
- Ribosomal protein l22 (11 kDa, Protein from Oryctolagus cuniculus)
- 5.8s ribosomal rna (50 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle proteins (Complex from Homo sapiens)
- Ribosomal protein l39 (6 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l13a (56 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l17 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
- Nascent chain preprolactin (Complex from Homo sapiens)
- Ul30 (26 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- Srp rna 7sl (Complex from Homo sapiens)
- Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
- El18 (21 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle subunit srp68 (70 kDa, Protein from Homo sapiens)
- El42 (16 kDa, Protein from Oryctolagus cuniculus)
- 5s ribosomal rna (38 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal_l23en domain-containing protein (17 kDa, Protein from Oryctolagus cuniculus)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- El43 (10 kDa, Protein from Oryctolagus cuniculus)
- L8 (26 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l32 (18 kDa, Protein from Oryctolagus cuniculus)
- Srp rna 7sl (54 kDa, RNA from Homo sapiens)
- Nascent chain preprolactin (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
- Nascent polypeptide-associated complex subunit alpha (23 kDa, Protein from Homo sapiens)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- Ubiquitin a-52 residue ribosomal protein fusion product 1 (14 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle 19 kda protein (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l28 (15 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle 54 kda protein (55 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (24 kDa, Protein from Oryctolagus cuniculus)
- Ternary ribosome-nascent chain srp nac complex (Complex)
- Ribosome (Complex from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (11 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
- Isoform 2 of transcription factor btf3 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l34 (14 kDa, Protein from Oryctolagus cuniculus)
- Ul3 (46 kDa, Protein from Homo sapiens)
- Isoform 2 of transcription factor btf3 (Complex from Homo sapiens)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
Structure of the ribosome-nascent chain containing an ER signal sequence in complex with NAC
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7qwr
Q-score: 0.454
Jomaa A, Gamerdinger M, Hsieh HH, Wallisch A, Chandrasekaran V, Ulusoy Z, Scaiola A, Hegde RS, Shan SO, Ban N, Deuerling E
Science (2022) 375 pp. 839-844 [ DOI: doi:10.1126/science.abl6459 Pubmed: 35201867 ]
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Ribosomal protein l32 (18 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l34 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l22 (12 kDa, Protein from Oryctolagus cuniculus)
- Isoform 2 of transcription factor btf3 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
- L13 (24 kDa, Protein from Oryctolagus cuniculus)
- El42 (16 kDa, Protein from Oryctolagus cuniculus)
- El43 (10 kDa, Protein from Oryctolagus cuniculus)
- 5.8s ribosomal rna (50 kDa, RNA from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- Ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- Nascent chain pre-prolactin (Complex from Homo sapiens)
- 60s ribosomal protein l13a (56 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l28 (15 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l30 (12 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l40 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (24 kDa, Protein from Oryctolagus cuniculus)
- El18 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (11 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- Ul30 (26 kDa, Protein from Oryctolagus cuniculus)
- Nascent chain pre-prolactin (2 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l8 (26 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
- 5s ribosomal rna (38 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
- Nascent polypeptide-associated complex subunit alpha (23 kDa, Protein from Homo sapiens)
- Isoform 2 of transcription factor btf3 (Complex from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l39 (6 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- Ribosome (Complex from Oryctolagus cuniculus)
- Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l17 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l18a (20 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal_l23en domain-containing protein (17 kDa, Protein from Oryctolagus cuniculus)
- Nascent polypeptide-associated complex subunit alpha (Complex from Homo sapiens)
- Ribosome-nascent chain containing an er signal sequence in complex with nac (Complex)
- 60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7qws
Q-score: -0.054
Jomaa A, Gamerdinger M, Hsieh HH, Wallisch A, Chandrasekaran V, Ulusoy Z, Scaiola A, Hegde RS, Shan SO, Ban N, Deuerling E
Science (2022) 375 pp. 839-844 [ DOI: doi:10.1126/science.abl6459 Pubmed: 35201867 ]
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- Ribosomal protein l32 (18 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l34 (14 kDa, Protein from Oryctolagus cuniculus)
- Ribosome translating beta-tubulin in complex with ttc5 and nac (Complex)
- Nascent chain tubulin beta (2 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
- El42 (16 kDa, Protein from Oryctolagus cuniculus)
- El43 (10 kDa, Protein from Oryctolagus cuniculus)
- 5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- Ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l28 (15 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l30 (12 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (24 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (11 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l13 (24 kDa, Protein from Oryctolagus cuniculus)
- Ul30 (26 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l40 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
- Nascent chain tubulin beta (Complex from Homo sapiens)
- 60s ribosomal protein l8 (26 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l13a (56 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l18a (20 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal_l18_c domain-containing protein (34 kDa, Protein from Oryctolagus cuniculus)
- 5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
- Tetratricopeptide repeat protein 5 (Complex from Homo sapiens)
- Tetratricopeptide repeat protein 5 (48 kDa, Protein from Homo sapiens)
- Nascent polypeptide-associated complex subunit alpha (23 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l18 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l39 (6 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- Ribosome (Complex from Oryctolagus cuniculus)
- Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l17 (17 kDa, Protein from Oryctolagus cuniculus)
- Transcription factor btf3 (17 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal_l23en domain-containing protein (17 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Ribosomal protein l22 (12 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7obr
Q-score: 0.492
Jomaa A, Eitzinger S, Zhu Z, Chandrasekar S, Kobayashi K, Shan SO, Ban N
Cell Rep (2021) 36 pp. 109350-109350 [ Pubmed: 34260909 DOI: doi:10.1016/j.celrep.2021.109350 ]
- 60s ribosomal protein l13 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l13a (23 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l34 (14 kDa, Protein from Oryctolagus cuniculus)
- 5.8s ribosomal rna (50 kDa, RNA from Oryctolagus cuniculus)
- El43 (10 kDa, Protein from Oryctolagus cuniculus)
- Rnc-srp complex (Complex from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- El32 (18 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- El28 (15 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle 54 kda protein (55 kDa, Protein from Canis lupus familiaris)
- 60s ribosomal protein l5 (34 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle 19 (16 kDa, Protein from Canis lupus familiaris)
- Signal recognition particle 9 kda protein (10 kDa, Protein from Canis lupus familiaris)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- El18 (21 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (24 kDa, Protein from Oryctolagus cuniculus)
- Ul29 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (11 kDa, Protein from Oryctolagus cuniculus)
- Ul30 (26 kDa, Protein from Oryctolagus cuniculus)
- El39 (6 kDa, Protein from Oryctolagus cuniculus)
- Ul15 (16 kDa, Protein from Oryctolagus cuniculus)
- Ul22 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l8 (26 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
- Rnc-srp complex (Complex from Canis lupus familiaris)
- El31 (14 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l24 (7 kDa, Protein from Oryctolagus cuniculus)
- 5s ribosomal rna (38 kDa, RNA from Oryctolagus cuniculus)
- El42 (12 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle subunit srp68 (70 kDa, Protein from Canis lupus familiaris)
- Dipeptidyl aminopeptidase b (7 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- El38 (8 kDa, Protein from Oryctolagus cuniculus)
- Ul3 (45 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein el19 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l30 (10 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (28 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- El21 (18 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle subunit srp72 (74 kDa, Protein from Canis lupus familiaris)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- Srp rna (80 kDa, RNA from Canis lupus familiaris)
- Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Oryctolagus cuniculus)
- Rnc-srp complex (Complex)
- Signal recognition particle 14 kda protein (12 kDa, Protein from Canis lupus familiaris)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Ribosomal protein l22 (11 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- Ul23 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l18a (20 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein el40 (6 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Polypeptide nascent chain (Complex from Saccharomyces cerevisiae)
- 60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7nfx
Q-score: 0.432
Lee JH, Jomaa A, Chung S, Hwang Fu YH, Qian R, Sun X, Hsieh HH, Chandrasekar S, Bi X, Mattei S, Boehringer D, Weiss S, Ban N, Shan SO
Sci Adv (2021) 7 [ DOI: doi:10.1126/sciadv.abg0942 Pubmed: 34020957 ]
- El39 (6 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle receptor subunit beta (29 kDa, Protein from Homo sapiens)
- Ribosome nascent chain complex with srp and srp receptor (3 MDa, Complex)
- Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle 54 kda protein (55 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle 19 kda protein (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- Ul3 (46 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (24 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l24 (7 kDa, Protein from Oryctolagus cuniculus)
- El42 (12 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle receptor subunit alpha (69 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Srp rna 7sl (96 kDa, RNA from Homo sapiens)
- El18 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l34 (14 kDa, Protein from Oryctolagus cuniculus)
- El20 (20 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- El43 (10 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- 5.8s ribosomal rna (50 kDa, RNA from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- El21 (18 kDa, Protein from Oryctolagus cuniculus)
- El31 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- El36 (12 kDa, Protein from Oryctolagus cuniculus)
- El28 (15 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle subunit srp68 (70 kDa, Protein from Homo sapiens)
- Ribosomal proteins (Complex from Oryctolagus cuniculus)
- Ul22 (17 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle subunit srp72 (74 kDa, Protein from Homo sapiens)
- Srp (Complex from Homo sapiens)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- Ul15 (16 kDa, Protein from Oryctolagus cuniculus)
- Ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Oryctolagus cuniculus)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Ul30 (26 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle 14 kda protein (14 kDa, Protein from Homo sapiens)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- Ul2 (26 kDa, Protein from Oryctolagus cuniculus)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
- Signal sequence (Complex from Homo sapiens)
- El30 (10 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle 9 kda protein (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein el19 (21 kDa, Protein from Oryctolagus cuniculus)
- Ul23 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l13 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- El38 (8 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein el40 (6 kDa, Protein from Oryctolagus cuniculus)
- 5s ribosomal rna (38 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l5 (34 kDa, Protein from Oryctolagus cuniculus)
- Ul29 (14 kDa, Protein from Oryctolagus cuniculus)
- Signal sequence (1 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l22 (11 kDa, Protein from Oryctolagus cuniculus)
- 28s ribosomal rna (1 MDa, RNA from Oryctolagus cuniculus)
- El32 (15 kDa, Protein from Oryctolagus cuniculus)