CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8rxh
Q-score: 0.603
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- P-site_trna_chain_s3 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- A-site_trna_chain_s2 (24 kDa, RNA from Leishmania major strain Friedlin)
- Mrna_chain_s5 (4 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- (2s)-2-[2-[4-[[(2r,3s,4s)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid (437 Da, Ligand)
- E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- Cryo-em structure of leishmania major 80s ribosome with a/p/e-site trna and mrna (Complex from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein s17 family protein (20 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8rxx
Q-score: 0.601
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ DOI: doi:10.1016/j.celrep.2024.114203 Pubmed: 38722744 ]
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- Mrna_chain_s5 (4 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein s17 family protein (20 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- 80s ribosome with a/p/e-site trna and mrna (Complex from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- P-site_trna_chain_s3 (24 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- A-site_trna_chain_s2 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : PARENTAL STRAIN
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8ovj
Q-score: 0.63
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ DOI: doi:10.1016/j.celrep.2024.114203 Pubmed: 38722744 ]
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- 80s ribosome from leishmania major (Complex from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s11 (20 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (6 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7obr
Q-score: 0.492
Jomaa A, Eitzinger S, Zhu Z, Chandrasekar S, Kobayashi K, Shan SO, Ban N
Cell Rep (2021) 36 pp. 109350-109350 [ Pubmed: 34260909 DOI: doi:10.1016/j.celrep.2021.109350 ]
- 60s ribosomal protein l13 (24 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l13a (23 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l34 (14 kDa, Protein from Oryctolagus cuniculus)
- 5.8s ribosomal rna (50 kDa, RNA from Oryctolagus cuniculus)
- El43 (10 kDa, Protein from Oryctolagus cuniculus)
- Rnc-srp complex (Complex from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- El32 (18 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- El28 (15 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle 54 kda protein (55 kDa, Protein from Canis lupus familiaris)
- 60s ribosomal protein l5 (34 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle 19 (16 kDa, Protein from Canis lupus familiaris)
- Signal recognition particle 9 kda protein (10 kDa, Protein from Canis lupus familiaris)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- El18 (21 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (24 kDa, Protein from Oryctolagus cuniculus)
- Ul29 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (11 kDa, Protein from Oryctolagus cuniculus)
- Ul30 (26 kDa, Protein from Oryctolagus cuniculus)
- El39 (6 kDa, Protein from Oryctolagus cuniculus)
- Ul15 (16 kDa, Protein from Oryctolagus cuniculus)
- Ul22 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l8 (26 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l4 (46 kDa, Protein from Oryctolagus cuniculus)
- Rnc-srp complex (Complex from Canis lupus familiaris)
- El31 (14 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l24 (7 kDa, Protein from Oryctolagus cuniculus)
- 5s ribosomal rna (38 kDa, RNA from Oryctolagus cuniculus)
- El42 (12 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle subunit srp68 (70 kDa, Protein from Canis lupus familiaris)
- Dipeptidyl aminopeptidase b (7 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- El38 (8 kDa, Protein from Oryctolagus cuniculus)
- Ul3 (45 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein el19 (21 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l30 (10 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l6 (28 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- El21 (18 kDa, Protein from Oryctolagus cuniculus)
- Signal recognition particle subunit srp72 (74 kDa, Protein from Canis lupus familiaris)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- Srp rna (80 kDa, RNA from Canis lupus familiaris)
- Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- El33 (12 kDa, Protein from Oryctolagus cuniculus)
- Rnc-srp complex (Complex)
- Signal recognition particle 14 kda protein (12 kDa, Protein from Canis lupus familiaris)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Ribosomal protein l22 (11 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- Ul23 (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l18a (20 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein el40 (6 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Polypeptide nascent chain (Complex from Saccharomyces cerevisiae)
- 60s ribosomal protein l7a (36 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
Structure of human ribosome in classical-PRE state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6y0g
Q-score: 0.488
Bhaskar V, Graff-Meyer A, Schenk AD, Cavadini S, von Loeffelholz O, Natchiar SK, Artus-Revel CG, Hotz HR, Bretones G, Klaholz BP, Chao JA
Cell Rep (2020) 31 pp. 107473-107473 [ Pubmed: 32268098 DOI: doi:10.1016/j.celrep.2020.03.037 ]
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- Human ribosomes in the classical-pre state (4 MDa, Complex from Homo sapiens)
- 40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- Nascent peptide (188 Da, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s30 (6 kDa, Protein from Homo sapiens)
- 18s ribosomal rna (602 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10-like (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
- Trna (24 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- 28s ribosomal rna (1 MDa, RNA from Homo sapiens)
- 40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
- 4-{(2r)-2-[(1s,3s,5s)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione (281 Da, Ligand)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
- 5.8s ribosomal rna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
- Mrna (8 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
Cryo-EM map of human ribosome in POST state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6y2l
Q-score: 0.537
Bhaskar V, Graff-Meyer A, Schenk AD, Cavadini S, von Loeffelholz O, Natchiar SK, Artus-Revel CG, Hotz HR, Bretones G, Klaholz BP, Chao JA
Cell Rep (2020) 31 pp. 107473-107473 [ Pubmed: 32268098 DOI: doi:10.1016/j.celrep.2020.03.037 ]
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
- Trna (24 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s30 (6 kDa, Protein from Homo sapiens)
- 28s ribosomal rna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 5s ribosomal rna (38 kDa, RNA from Homo sapiens)
- Mrna (8 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- 40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
- Human ribosomes in the classical-pre state (4 MDa, Complex from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10-like (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- 4-{(2r)-2-[(1s,3s,5s)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione (281 Da, Ligand)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 5.8s ribosomal rna (50 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- 18s ribosomal rna (602 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- Nascent polypeptide (188 Da, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
Cryo-EM map of human ribosome in hybrid-PRE state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6y57
Q-score: 0.462
Bhaskar V, Graff-Meyer A, Schenk AD, Cavadini S, von Loeffelholz O, Natchiar SK, Artus-Revel CG, Hotz HR, Bretones G, Klaholz BP, Chao JA
Cell Rep (2020) 31 pp. 107473-107473 [ DOI: doi:10.1016/j.celrep.2020.03.037 Pubmed: 32268098 ]
- 40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- 60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 18s ribosomal rna (602 kDa, RNA from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
- A/p trna (24 kDa, RNA from Homo sapiens)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- Mrna (4 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 5s ribosomal rna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 5.8s ribosomal rna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s30 (6 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- Human ribosomes in the classical-pre state (4 MDa, Complex from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- 28s ribosomal rna (1 MDa, RNA from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10-like (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
- P/e trna (24 kDa, RNA from Homo sapiens)