Yeast 80S, ES7s delta, eIF5A, Stm1 containing
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8bn3
Q-score: 0.597
Rauscher R, Eggers C, Dimitrova-Paternoga L, Shankar V, Rosina A, Cristodero M, Paternoga H, Wilson DN, Leidel SA, Polacek N
Nucleic Acids Res (2024) 52 pp. 4021-4036 [ Pubmed: 38324474 DOI: doi:10.1093/nar/gkae067 ]
- Rps22a isoform 1 (14 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es1 (24 kDa, Protein from Saccharomyces cerevisiae)
- Rps20 isoform 1 (12 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l21-a (18 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l3 (43 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l27-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l8-a (25 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l39 (6 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es4a (29 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l43-a (9 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l36-a (11 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l18-a (20 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s3 (24 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el41b (3 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l35-a (13 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s27-a (8 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l28 (16 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s30-a (6 kDa, Protein from Saccharomyces cerevisiae)
- Eukaryotic translation initiation factor 5a (15 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l31-a (12 kDa, Protein from Saccharomyces cerevisiae)
- 5.8s ribosomal rna (50 kDa, RNA from Saccharomyces cerevisiae)
- Rpl4a isoform 1 (39 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Spermidine (145 Da, Ligand)
- Dormant yeast 80s ribosome (3 MDa, Complex from Saccharomyces cerevisiae)
- 5s ribosomal rna (38 kDa, RNA from Saccharomyces cerevisiae)
- 25s ribosomal rna (1 MDa, RNA from Saccharomyces cerevisiae)
- 40s ribosomal protein s19-a (15 kDa, Protein from Saccharomyces cerevisiae)
- Es17 (13 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es10a (11 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s14-b (13 kDa, Protein from Saccharomyces cerevisiae)
- Rps5p (22 kDa, Protein from Saccharomyces cerevisiae)
- Rpl24a isoform 1 (11 kDa, Protein from Saccharomyces cerevisiae)
- Rps26b isoform 1 (11 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s23-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l29 (6 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l7-a (25 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el34a (12 kDa, Protein from Saccharomyces cerevisiae)
- 18s ribosomal rna (559 kDa, RNA from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us4a (21 kDa, Protein from Saccharomyces cerevisiae)
- Rpl32 isoform 1 (14 kDa, Protein from Saccharomyces cerevisiae)
- Stm1 isoform 1 (12 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein el37a (9 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us17a (17 kDa, Protein from Saccharomyces cerevisiae)
- 4-{(2r)-2-[(1s,3s,5s)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione (281 Da, Ligand)
- Rpl11b isoform 1 (19 kDa, Protein from Saccharomyces cerevisiae)
- Rps2 isoform 1 (23 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s16-a (15 kDa, Protein from Saccharomyces cerevisiae)
- Water (18 Da, Ligand)
- 40s ribosomal protein s13 (16 kDa, Protein from Saccharomyces cerevisiae)
- Rpl5 isoform 1 (33 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l33-a (12 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l13-a (21 kDa, Protein from Saccharomyces cerevisiae)
- Rps15 isoform 1 (14 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l2-a (27 kDa, Protein from Saccharomyces cerevisiae)
- Rpl38 isoform 1 (8 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es21a (9 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s25 (8 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l14-a (14 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein rack1 (34 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us2a (27 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l42-a (12 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l30 (10 kDa, Protein from Saccharomyces cerevisiae)
- Ribosomal protein l15 (24 kDa, Protein from Saccharomyces cerevisiae)
- Rpl10 isoform 1 (24 kDa, Protein from Saccharomyces cerevisiae)
- Rps29a isoform 1 (6 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l22-a (11 kDa, Protein from Saccharomyces cerevisiae)
- Potassium ion (39 Da, Ligand)
- 60s ribosomal protein l16-a (22 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l6-a (17 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l17-a (20 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s18-a (16 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l1-a (24 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l20-a (20 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l25 (13 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s7-a (21 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es6a (25 kDa, Protein from Saccharomyces cerevisiae)
- Rpl9a isoform 1 (21 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s24-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l19-a (21 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l23-a (14 kDa, Protein from Saccharomyces cerevisiae)
- Rps28a isoform 1 (7 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s8 (21 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l40-a (6 kDa, Protein from Saccharomyces cerevisiae)
- Rps31 isoform 1 (8 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l41-a (2 kDa, Protein from Saccharomyces cerevisiae)
- Large ribosomal subunit protein ul24a (14 kDa, Protein from Saccharomyces cerevisiae)
Context-specific inhibition of eukaryotic translation by macrolide antibiotics
Resolution: 2.877 Å
EM Method: Single-particle
Fitted PDBs: 7azy
Q-score: 0.58
Svetlov MS, Koller TO, Meydan S, Shankar V, Klepacki D, Polacek N, Guydosh NR, Vazquez-Laslop N, Wilson DN, Mankin AS
Nat Commun (2021) 12 pp. 2803-2803 [ Pubmed: 33990576 DOI: doi:10.1038/s41467-021-23068-1 ]
- 60s ribosomal protein l8-a (28 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l6-a (20 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l32 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 5s ribosomal rna (38 kDa, RNA from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l2-a (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l35-a (13 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l34-a (13 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l19-a (21 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Water (18 Da, Ligand)
- 60s ribosomal protein l5 (33 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l3 (43 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l39 (6 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l37-a (9 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Telithromycin (812 Da, Ligand)
- 60s ribosomal protein l28 (16 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l36-a (11 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l23-a (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l21-a (18 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l9-a (21 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l24-a (17 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l29 (6 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l33-a (12 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l31-a (12 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l27-a (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 25s ribosomal rna (1 MDa, RNA from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 5.8s ribosomal rna (50 kDa, RNA from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l10 (25 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l16-a (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l13-a (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l20-a (20 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l18-a (20 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l43-a (10 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l38 (8 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l4-a (39 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l22-a (13 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l17-a (20 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal subunit with 25s rrna mutation g2400a and telithromycin bound in the nascent peptide exit tunnel (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l26-a (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l42-a (12 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l11-b (19 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l25 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l15-a (24 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l7-a (27 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 60s ribosomal protein l14-a (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7nrc
Q-score: 0.378
Pochopien AA, Beckert B, Kasvandik S, Berninghausen O, Beckmann R, Tenson T, Wilson DN
PNAS (2021) 118 [ Pubmed: 33790014 DOI: doi:10.1073/pnas.2022756118 ]
- 60s ribosomal protein l8-a (25 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l5 (33 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s7-a (21 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s31 (8 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l9-a (21 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l35-a (13 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s1-a (26 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s21-a (9 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s28-a (7 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l19-a (21 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l23-a (14 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s15 (13 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l10 (25 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l17-a (20 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l30 (10 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l27-a (15 kDa, Protein from Saccharomyces cerevisiae S288C)
- Eif5a (16 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s14-b (13 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l26-a (14 kDa, Protein from Saccharomyces cerevisiae S288C)
- Gir2 (4 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l40-a (6 kDa, Protein from Saccharomyces cerevisiae S288C)
- 5s rrna (121-mer) (38 kDa, RNA from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s11-a (16 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s3 (24 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l18-a (20 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s25-a (9 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l4-a (39 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l14-a (14 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l16-a (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s6-a (26 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s4-a (29 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l2-a (27 kDa, Protein from Saccharomyces cerevisiae S288C)
- L1 60s ribosomal protein (17 kDa, Protein from Saccharomyces cerevisiae S288C)
- Structure of the yeast gcn1-bound leading stalled 80s ribosome with bound rbg2, gir2, a- and p-trna and eif5a (Complex from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s9-a (21 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s24-a (15 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l29 (6 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s16-a (15 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l25 (13 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s12 (13 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l36-a (11 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l37-a (9 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l7-a (25 kDa, Protein from Saccharomyces cerevisiae S288C)
- 25s rrna (3184-mer) (1 MDa, RNA from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s23-a (15 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s19-a (15 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l24-a (7 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s20 (11 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s27-a (8 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s5 (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l20-a (20 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s30-a (6 kDa, Protein from Saccharomyces cerevisiae S288C)
- 18s rrna (1771-mer) (579 kDa, RNA from Saccharomyces cerevisiae S288C)
- Rna (5'-r(p*ap*up*gp*ap*ap*a)-3') (1 kDa, RNA from Saccharomyces cerevisiae S288C)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s0-a (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- Trna (75-mer) (24 kDa, RNA from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l33-a (12 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s10-a (11 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l34-a (12 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s13 (16 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l28 (16 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s26-b (11 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l39 (6 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l31-a (12 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s29-a (6 kDa, Protein from Saccharomyces cerevisiae S288C)
- Gcn1 (98 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l11-b (19 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s17-b (14 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s2 (23 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l42-a (11 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l32 (14 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s18-a (16 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l38 (8 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l43-a (9 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s8-a (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l15-a (24 kDa, Protein from Saccharomyces cerevisiae S288C)
- 40s ribosomal protein s22-a (14 kDa, Protein from Saccharomyces cerevisiae S288C)
- Trna (76-mer) (24 kDa, RNA from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l6-b (19 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l13-a (21 kDa, Protein from Saccharomyces cerevisiae S288C)
- 5.8s rrna (158-mer) (50 kDa, RNA from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l22-a (11 kDa, Protein from Saccharomyces cerevisiae S288C)
- Ribosome-interacting gtpase 2 (40 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l21-a (18 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l41-a (3 kDa, Protein from Saccharomyces cerevisiae S288C)
- 60s ribosomal protein l3 (43 kDa, Protein from Saccharomyces cerevisiae S288C)
Resolution: 4.36 Å
EM Method: Single-particle
Fitted PDBs: 7nrd
Q-score: 0.363
Pochopien AA, Beckert B, Kasvandik S, Berninghausen O, Beckmann R, Tenson T, Wilson DN
PNAS (2021) 118 [ Pubmed: 33790014 DOI: doi:10.1073/pnas.2022756118 ]
- 40s ribosomal protein s20 (11 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s27-a (8 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s24-a (15 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l11-b (19 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s18-a (16 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l37-a (9 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l14-a (14 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l20-a (20 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s21-a (9 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l24-a (7 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l13-a (21 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s19-a (15 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s12 (13 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s14-b (13 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l38 (8 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s16-a (15 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l5 (33 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l19-a (21 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l34-a (12 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l39 (6 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s29-a (6 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s25-a (7 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s5 (22 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l22-a (11 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l43-a (9 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s28-a (7 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s26-b (11 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s4-a (29 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l42-a (11 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l16-a (22 kDa, Protein from Baker's yeast)
- 25s rrna (3184-mer) (1 MDa, RNA from Saccharomyces cerevisiae S288C)
- Mrna (32-mer) (9 kDa, RNA from Saccharomyces cerevisiae S288c)
- 40s ribosomal protein s30-a (5 kDa, Protein from Baker's yeast)
- 5s rrna (121-mer) (38 kDa, RNA from Saccharomyces cerevisiae S288c)
- Multiprotein-bridging factor 1 (13 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s2 (23 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s9-a (21 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l7-a (25 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l18-a (20 kDa, Protein from Baker's yeast)
- Tpa_inf: saccharomyces cerevisiae s288c chromosome xii, complete sequence (579 kDa, RNA from Saccharomyces cerevisiae S288C)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l36-a (11 kDa, Protein from Baker's yeast)
- Ubiquitin-40s ribosomal protein s31 (8 kDa, Protein from Baker's yeast)
- Structure of the yeast gcn1-bound coilliding stalled 80s ribosome with mbf1, gir2, a/p-trna and p/e-trna (Complex from Saccharomyces cerevisiae S288c)
- 40s ribosomal protein s10-a (11 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l17-a (20 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l41-b (3 kDa, Protein from Baker's yeast)
- Trna (75-mer) (24 kDa, RNA from Baker's yeast)
- 60s ribosomal protein l32 (14 kDa, Protein from Baker's yeast)
- Ubiquitin-60s ribosomal protein l40 (6 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l25 (13 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s13 (16 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s6-a (24 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l15-a (24 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l4-a (39 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l26-a (14 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s8-a (21 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l8-a (25 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l31-a (12 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s11-a (16 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l2-a (27 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l23-a (14 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l29 (6 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l6-b (18 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s1-a (24 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s17-b (14 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s15 (13 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l3 (43 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l10 (25 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l33-a (12 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s3 (24 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l28 (16 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l21-a (18 kDa, Protein from Baker's yeast)
- 5.8s rrna (158-mer) (50 kDa, RNA from Saccharomyces cerevisiae S288c)
- 60s ribosomal protein l9-a (21 kDa, Protein from Baker's yeast)
- Trna (77-mer) (24 kDa, RNA from Saccharomyces cerevisiae S288c)
- 60s ribosomal protein l30 (10 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s0-a (22 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s23-a (15 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s7-a (21 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l35-a (13 kDa, Protein from Baker's yeast)
- 40s ribosomal protein s22-a (14 kDa, Protein from Baker's yeast)
- 60s ribosomal protein l27-a (15 kDa, Protein from Baker's yeast)
Tetracenomycin X bound to the human ribosome
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6y6x
Q-score: 0.546
Osterman IA, Wieland M, Maviza TP, Lashkevich KA, Lukianov DA, Komarova ES, Zakalyukina YV, Buschauer R, Shiriaev DI, Leyn SA, Zlamal JE, Biryukov MV, Skvortsov DA, Tashlitsky VN, Polshakov VI, Cheng J, Polikanov YS, Bogdanov AA, Osterman AL, Dmitriev SE, Beckmann R, Dontsova OA, Wilson DN, Sergiev PV
Nat Chem Biol (2020) 16 pp. 1071-1077 [ DOI: doi:10.1038/s41589-020-0578-x Pubmed: 32601485 ]
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (13 kDa, Protein from Homo sapiens)
- Tetracenomycin x (486 Da, Ligand)
- 60s ribosomal protein l7a (27 kDa, Protein from Homo sapiens)
- Ubiquitin-60s ribosomal protein l40 (6 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (11 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l30 (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10-like (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l10a (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (13 kDa, Protein from Homo sapiens)
- 28s ribosomal rna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l31 (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (45 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (26 kDa, Protein from Homo sapiens)
- 5s ribosomal rna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l14 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (41 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- Tetracenomycin bound to the human ribosome (Complex from Homo sapiens)
- 60s ribosomal protein l24 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (26 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (11 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (14 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 5.8s ribosomal rna (50 kDa, RNA from Homo sapiens)