Structure of Candida albicans 80S ribosome in complex with mefloquine
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8ogj
Q-score: 0.366
Kolosova O, Zgadzay Y, Yusupov M
To Be Published
- 40s ribosomal protein s27 (8 kDa, Protein from Candida albicans)
- 60s ribosomal protein l11-b (19 kDa, Protein from Candida albicans)
- 40s ribosomal protein s6 (27 kDa, Protein from Candida albicans)
- 40s ribosomal protein s18-b (17 kDa, Protein from Candida albicans)
- 60s ribosomal protein l38 (8 kDa, Protein from Candida albicans)
- 40s ribosomal protein s1 (29 kDa, Protein from Candida albicans)
- Candida albicans 80s ribosome in complex with mefloquine (3 MDa, Complex from Candida albicans)
- 60s ribosomal protein l2-b (27 kDa, Protein from Candida albicans)
- Ribosomal protein s23 (s12) (16 kDa, Protein from Candida albicans)
- 40s ribosomal protein s10-a (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s0 (28 kDa, Protein from Candida albicans)
- 60s ribosomal protein l13 (23 kDa, Protein from Candida albicans)
- 60s ribosomal protein l41 (3 kDa, Protein from Candida albicans)
- Mixture of endogenous e-trnas (24 kDa, RNA from Candida albicans)
- 40s ribosomal protein s24 (15 kDa, Protein from Candida albicans)
- 60s ribosomal protein l24-a (17 kDa, Protein from Candida albicans)
- 40s ribosomal protein s25 (11 kDa, Protein from Candida albicans)
- 60s ribosomal protein l28 (16 kDa, Protein from Candida albicans)
- Zinc ion (65 Da, Ligand)
- 18s ribosomal rna (575 kDa, RNA from Candida albicans)
- 60s ribosomal protein l42-b (12 kDa, Protein from Candida albicans)
- 40s ribosomal protein s28-b (7 kDa, Protein from Candida albicans)
- 60s ribosomal protein l3 (44 kDa, Protein from Candida albicans)
- 60s ribosomal protein l29 (7 kDa, Protein from Candida albicans)
- 60s ribosomal protein l9-b (21 kDa, Protein from Candida albicans)
- Spermine (fully protonated form) (206 Da, Ligand)
- 60s ribosomal protein l14-b (14 kDa, Protein from Candida albicans)
- 40s ribosomal protein s8 (22 kDa, Protein from Candida albicans)
- 60s ribosomal protein l23-a (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l39 (6 kDa, Protein from Candida albicans)
- 60s ribosomal protein l36 (11 kDa, Protein from Candida albicans)
- (11r,12s)- mefloquine (378 Da, Ligand)
- 60s ribosomal protein l34-b (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s30 (7 kDa, Protein from Candida albicans)
- 60s ribosomal protein l27 (15 kDa, Protein from Candida albicans)
- 40s ribosomal protein s22-a (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l6 (19 kDa, Protein from Candida albicans)
- 60s ribosomal protein l37-b (10 kDa, Protein from Candida albicans)
- Ribosomal protein l29 (14 kDa, Protein from Candida albicans)
- 40s ribosomal protein s11a (17 kDa, Protein from Candida albicans)
- 40s ribosomal protein s21 (9 kDa, Protein from Candida albicans)
- 5s ribosomal rna (38 kDa, RNA from Candida albicans)
- 25s ribosomal rna (1 MDa, RNA from Candida albicans)
- 40s ribosomal protein s12 (15 kDa, Protein from Candida albicans)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Candida albicans)
- 40s ribosomal protein s14-a (14 kDa, Protein from Candida albicans)
- Ubiquitin-40s ribosomal protein s31 fusion protein (22 kDa, Protein from Candida albicans)
- 60s ribosomal protein l20 (20 kDa, Protein from Candida albicans)
- 60s ribosomal protein l33-a (12 kDa, Protein from Candida albicans)
- 60s ribosomal protein l5 (34 kDa, Protein from Candida albicans)
- 60s ribosomal protein l25 (15 kDa, Protein from Candida albicans)
- Ribosomal protein s5 (26 kDa, Protein from Candida albicans)
- 40s ribosomal protein s16 (15 kDa, Protein from Candida albicans)
- 60s ribosomal protein l7-a (27 kDa, Protein from Candida albicans)
- 40s ribosomal protein s7 (21 kDa, Protein from Candida albicans)
- Ribosomal protein s4 (21 kDa, Protein from Candida albicans)
- Ribosomal protein l24 (14 kDa, Protein from Candida albicans)
- 40s ribosomal protein s19-a (16 kDa, Protein from Candida albicans)
- Ribosomal protein s7 (25 kDa, Protein from Candida albicans)
- Magnesium ion (24 Da, Ligand)
- 40s ribosomal protein s29a (6 kDa, Protein from Candida albicans)
- 60s ribosomal protein l19-a (21 kDa, Protein from Candida albicans)
- Ribosomal protein s3 (27 kDa, Protein from Candida albicans)
- 60s ribosomal protein l31-b (12 kDa, Protein from Candida albicans)
- 60s ribosomal protein l15-a (24 kDa, Protein from Candida albicans)
- 60s ribosomal protein l21-a (18 kDa, Protein from Candida albicans)
- Ribosomal protein l22 (21 kDa, Protein from Candida albicans)
- 40s ribosomal protein s13 (16 kDa, Protein from Candida albicans)
- 60s ribosomal protein l18-a (20 kDa, Protein from Candida albicans)
- 60s ribosomal protein l32 (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l4-b (39 kDa, Protein from Candida albicans)
- 60s ribosomal protein l22-b (14 kDa, Protein from Candida albicans)
- 60s ribosomal protein l40-b (6 kDa, Protein from Candida albicans)
- 60s ribosomal protein l10 (25 kDa, Protein from Candida albicans)
- 60s ribosomal protein l43-a (10 kDa, Protein from Candida albicans)
- Ribosomal protein s10 (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s26 (13 kDa, Protein from Candida albicans)
- 40s ribosomal protein s4 (29 kDa, Protein from Candida albicans)
- Ribosomal protein l13 (22 kDa, Protein from Candida albicans)
- 40s ribosomal protein s15 (15 kDa, Protein from Candida albicans)
- 40s ribosomal protein s17-b (15 kDa, Protein from Candida albicans)
- 5.8s ribosomal rna (50 kDa, RNA from Candida albicans)
- 60s ribosomal protein l8 (28 kDa, Protein from Candida albicans)
- 60s ribosomal protein l30 (11 kDa, Protein from Candida albicans)
Drosophila melanogaster Testis 80S ribosome
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6xu6
Q-score: 0.441
Hopes T, Norris K, Agapiou M, McCarthy CGP, Lewis PA, O'Connell MJ, Fontana J, Aspden JL
Nucleic Acids Res (2022) 50 pp. 2240-2257 [ DOI: doi:10.1093/nar/gkab606 Pubmed: 34283226 ]
- 60s ribosomal protein l29 (8 kDa, Protein from Drosophila melanogaster)
- 28s ribosomal rna (1 MDa, RNA from Drosophila melanogaster)
- Lp04564p (41 kDa, Protein from Drosophila melanogaster)
- 5.8s ribosomal rna (39 kDa, RNA from Drosophila melanogaster)
- 40s ribosomal protein s24 (14 kDa, Protein from Drosophila melanogaster)
- Re62581p (18 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l18 (21 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l7 (26 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s20 (11 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l28 (14 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s4 (29 kDa, Protein from Drosophila melanogaster)
- 2s ribosomal rna (9 kDa, RNA from Drosophila melanogaster)
- 40s ribosomal protein s3a (25 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l27a (17 kDa, Protein from Drosophila melanogaster)
- Geo07455p1 (17 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l10 (25 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l32 (15 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s28 (7 kDa, Protein from Drosophila melanogaster)
- Re25263p (11 kDa, Protein from Drosophila melanogaster)
- Geo07301p1 (14 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l9 (21 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s18 (15 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l18a (20 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s16 (16 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l19 (24 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l11 (20 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l3 (46 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s12 (13 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s7 (22 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s17 (14 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l41 (3 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l7a (27 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s26 (12 kDa, Protein from Drosophila melanogaster)
- Ip17216p (13 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s10b (10 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l17 (21 kDa, Protein from Drosophila melanogaster)
- Ubiquitin-60s ribosomal protein l40 (6 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l4 (44 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l39 (6 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s15aa (14 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l27 (15 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l13 (24 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s5a (21 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l5 (33 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s3 (25 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s8 (23 kDa, Protein from Drosophila melanogaster)
- Guanine nucleotide-binding protein subunit beta-like protein (35 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s19a (16 kDa, Protein from Drosophila melanogaster)
- Geo07453p1 (15 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s27 (9 kDa, Protein from Drosophila melanogaster)
- Probable 60s ribosomal protein l37-b (9 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s25 (8 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l23 (14 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s23 (16 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s9 (21 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s30 (6 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s11 (18 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s29 (6 kDa, Protein from Drosophila melanogaster)
- Drosophila melanogaster testis 80s ribosome (Complex from Drosophila melanogaster)
- 40s ribosomal protein sa (24 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l15 (24 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l10a-2 (24 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s6 (26 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s2 (24 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l36 (13 kDa, Protein from Drosophila melanogaster)
- Ubiquitin-40s ribosomal protein s27a (9 kDa, Protein from Drosophila melanogaster)
- Ta01007p (12 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s13 (17 kDa, Protein from Drosophila melanogaster)
- 18s ribosomal rna (641 kDa, RNA from Drosophila melanogaster)
- 60s ribosomal protein l8 (27 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s14a (13 kDa, Protein from Drosophila melanogaster)
- Rh48056p (12 kDa, Protein from Drosophila melanogaster)
- Ribosomal protein l22-like protein (11 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l38 (8 kDa, Protein from Drosophila melanogaster)
- Fi02809p (14 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l37a (10 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s21 (8 kDa, Protein from Drosophila melanogaster)
- Ribosomal protein l6, isoform a (26 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l24 (6 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l13a (23 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l14 (18 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l31 (12 kDa, Protein from Drosophila melanogaster)
- 5s ribosomal rna (38 kDa, RNA from Drosophila melanogaster)
Drosophila melanogaster Testis polysome ribosome
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 6xu7
Q-score: 0.308
Hopes T, Norris K, Agapiou M, McCarthy CGP, Lewis PA, O'Connell MJ, Fontana J, Aspden JL
Nucleic Acids Res (2022) 50 pp. 2240-2257 [ DOI: doi:10.1093/nar/gkab606 Pubmed: 34283226 ]
- 40s ribosomal protein s16 (16 kDa, Protein from Drosophila melanogaster)
- Probable 60s ribosomal protein l37-b (9 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l13 (24 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l17 (21 kDa, Protein from Drosophila melanogaster)
- Geo07453p1 (15 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein sa (24 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l39 (6 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l10a-2 (24 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l11 (20 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s20 (11 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l29 (8 kDa, Protein from Drosophila melanogaster)
- Ubiquitin-60s ribosomal protein l40 (6 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s6 (26 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s30 (6 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l28 (14 kDa, Protein from Drosophila melanogaster)
- Fi02809p (14 kDa, Protein from Drosophila melanogaster)
- Geo07301p1 (14 kDa, Protein from Drosophila melanogaster)
- 2s ribosomal rna (9 kDa, RNA from Drosophila melanogaster)
- 40s ribosomal protein s15aa (14 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l36 (13 kDa, Protein from Drosophila melanogaster)
- Ribosomal protein l6, isoform a (26 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l4 (44 kDa, Protein from Drosophila melanogaster)
- Re62581p (18 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l9 (21 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s2 (24 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l41 (3 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l19 (24 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s27 (9 kDa, Protein from Drosophila melanogaster)
- 28s ribosomal rna (1 MDa, RNA from Drosophila melanogaster)
- 40s ribosomal protein s8 (23 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l27 (15 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l7 (26 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l23 (14 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s7 (22 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s29 (6 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s3a (25 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s17 (14 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s10b (10 kDa, Protein from Drosophila melanogaster)
- Geo07455p1 (17 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l18a (20 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l3 (46 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l24 (6 kDa, Protein from Drosophila melanogaster)
- Ta01007p (12 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s21 (8 kDa, Protein from Drosophila melanogaster)
- Guanine nucleotide-binding protein subunit beta-like protein (35 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l5 (33 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s11 (18 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s13 (17 kDa, Protein from Drosophila melanogaster)
- P-trna (24 kDa, RNA from Drosophila melanogaster)
- 60s ribosomal protein l27a (17 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s12 (13 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s18 (16 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l10 (25 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l18 (21 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l32 (15 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s28 (7 kDa, Protein from Drosophila melanogaster)
- 18s ribosomal rna (641 kDa, RNA from Drosophila melanogaster)
- 5s ribosomal rna (38 kDa, RNA from Drosophila melanogaster)
- 40s ribosomal protein s14a (14 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l31 (13 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l13a (23 kDa, Protein from Drosophila melanogaster)
- Ubiquitin-40s ribosomal protein s27a (9 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s19a (16 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s4 (29 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s5a (21 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s23 (16 kDa, Protein from Drosophila melanogaster)
- 5.8s ribosomal rna (39 kDa, RNA from Drosophila melanogaster)
- 60s ribosomal protein l14 (18 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l38 (8 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l8 (27 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s3 (25 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s24 (14 kDa, Protein from Drosophila melanogaster)
- Rh48056p (12 kDa, Protein from Drosophila melanogaster)
- Mrna (3 kDa, RNA from Drosophila melanogaster)
- 40s ribosomal protein s9 (21 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l7a (27 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l15 (24 kDa, Protein from Drosophila melanogaster)
- 40s ribosomal protein s25 (8 kDa, Protein from Drosophila melanogaster)
- Ip17216p (13 kDa, Protein from Drosophila melanogaster)
- 60s ribosomal protein l37a (10 kDa, Protein from Drosophila melanogaster)
- Re25263p (11 kDa, Protein from Drosophila melanogaster)
- Ribosomal protein l22-like protein (11 kDa, Protein from Drosophila melanogaster)
- Drosophila melanogaster testis polysome ribosome (Complex from Drosophila melanogaster)
- 40s ribosomal protein s26 (12 kDa, Protein from Drosophila melanogaster)