CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mutant snoRNA overexpression, class 4
Resolution: 2.43 Å
EM Method: Single-particle
Fitted PDBs: 8qie
Q-score: 0.655
To Be Published
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Cryo-em structure of leishmania major 80s ribosome : lm32cs1c1 mutant snorna overexpression, class 4 (Complex from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s11 (20 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8rxh
Q-score: 0.603
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- P-site_trna_chain_s3 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- A-site_trna_chain_s2 (24 kDa, RNA from Leishmania major strain Friedlin)
- Mrna_chain_s5 (4 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- (2s)-2-[2-[4-[[(2r,3s,4s)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid (437 Da, Ligand)
- E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- Cryo-em structure of leishmania major 80s ribosome with a/p/e-site trna and mrna (Complex from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein s17 family protein (20 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8rxx
Q-score: 0.601
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ DOI: doi:10.1016/j.celrep.2024.114203 Pubmed: 38722744 ]
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- Mrna_chain_s5 (4 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein s17 family protein (20 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- 80s ribosome with a/p/e-site trna and mrna (Complex from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- P-site_trna_chain_s3 (24 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- A-site_trna_chain_s2 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : PARENTAL STRAIN
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8ovj
Q-score: 0.63
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ DOI: doi:10.1016/j.celrep.2024.114203 Pubmed: 38722744 ]
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- 80s ribosome from leishmania major (Complex from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s11 (20 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (6 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
Chaetomium thermophilum Methionine Aminopeptidase 2 autoproteolysis product at the 80S ribosome
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8oo0
Q-score: 0.494
Klein MA, Wild K, Kisonaite M, Sinning I
Nat Commun (2024) 15 pp. 716-716 [ DOI: doi:10.1038/s41467-024-44862-7 Pubmed: 38267453 ]
- 60s ribosomal protein l41-a (3 kDa, Protein from Thermochaetoides thermophila)
- 5.8s rrna (50 kDa, RNA from Thermochaetoides thermophila DSM 1495)
- Ribosomal protein l37 (10 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l23-like protein (14 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s29 (6 kDa, Protein from Thermochaetoides thermophila)
- Putative ribosomal protein (17 kDa, Protein from Thermochaetoides thermophila)
- Ribosome-associated molecular chaperone ssb1 (67 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l38 (9 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s9-like protein (22 kDa, Protein from Thermochaetoides thermophila)
- Ribosomal protein l18e/l15p domain-containing protein (16 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s22-like protein (14 kDa, Protein from Thermochaetoides thermophila)
- Ubiquitin-like domain-containing protein (14 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s27a-like protein (17 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l9-like protein (21 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l39 (6 kDa, Protein from Thermochaetoides thermophila)
- 60s acidic ribosomal protein p0 (33 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s0 (31 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s14-like protein (16 kDa, Protein from Thermochaetoides thermophila)
- 28s rrna (1 MDa, RNA from Thermochaetoides thermophila)
- Dolichyl-diphosphooligosaccharide--protein glycotransferase (14 kDa, Protein from Thermochaetoides thermophila)
- Putative 60s ribosomal protein (13 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s28-like protein (7 kDa, Protein from Thermochaetoides thermophila)
- Putative 60s ribosomal protein (15 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l29 (7 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s1 (29 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l7-like protein (28 kDa, Protein from Thermochaetoides thermophila)
- 18s rrna (578 kDa, RNA from Thermochaetoides thermophila DSM 1495)
- 40s ribosomal protein s26 (13 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l25-like protein (17 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s8 (23 kDa, Protein from Thermochaetoides thermophila)
- Ribosomal protein s27-like protein (8 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l12-like protein (17 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l36 (12 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l14-like protein (16 kDa, Protein from Thermochaetoides thermophila)
- Methionine aminopeptidase 2 (41 kDa, Protein from Thermochaetoides thermophila)
- Putative ribosomal protein (20 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s10-like protein (18 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l26-like protein (15 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s23-like protein (15 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l30-like protein (11 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s13-like protein (16 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l33-like protein (12 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l17-like protein (20 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s17-like protein (16 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s16-like protein (15 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s12 (15 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l3-like protein (44 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s2-like protein (28 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l20 (20 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s25 (10 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s24 (15 kDa, Protein from Thermochaetoides thermophila)
- Map2 autoproteolysis product in complex with the 80s ribosome (Complex from Thermochaetoides thermophila)
- 40s ribosomal protein s19-like protein (17 kDa, Protein from Thermochaetoides thermophila)
- Zinc ion (65 Da, Ligand)
- 40s ribosomal protein s30 (6 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s6 (27 kDa, Protein from Thermochaetoides thermophila)
- Ribosomal protein l18-like protein (24 kDa, Protein from Thermochaetoides thermophila)
- 5s rrna (38 kDa, RNA from Thermochaetoides thermophila DSM 1495)
- 60s ribosomal protein l4-like protein (39 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l16-like protein (23 kDa, Protein from Thermochaetoides thermophila)
- Ribosomal protein l34-like protein (13 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l10-like protein (25 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s20-like protein (13 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l44-like protein (12 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l27 (15 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s7 (23 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s3-like protein (27 kDa, Protein from Thermochaetoides thermophila)
- Putative guanine nucleotide-binding protein (35 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s5-like protein (23 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s4 (29 kDa, Protein from Thermochaetoides thermophila)
- Ribosomal protein l19 (22 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l5-like protein (35 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l6 (22 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l21-like protein (18 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l22-like protein (14 kDa, Protein from Thermochaetoides thermophila)
- Hyaluronan/mrna-binding protein domain-containing protein (32 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l32-like protein (15 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l8 (29 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l43-like protein (10 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s11-like protein (18 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l2-like protein (27 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l13 (24 kDa, Protein from Thermochaetoides thermophila)
- 60s ribosomal protein l24 (18 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s21-like protein (10 kDa, Protein from Thermochaetoides thermophila)
- 40s ribosomal protein s15-like protein (17 kDa, Protein from Thermochaetoides thermophila)
- Ribosomal protein l15 (24 kDa, Protein from Thermochaetoides thermophila)
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8a3w
Q-score: 0.607
To Be Published
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Cryo-em structure of leishmania major 80s ribosome wild type (Complex from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (6 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- Ul30_chain_c (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (576 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (491 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Small ribosomal subunit protein rack1 (34 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- El13_chain_i (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s11 (20 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
CRYO-EM STRUCTURE OF TRYPANOSOMA BRUCEI PROCYCLIC FORM 80S RIBOSOME : PARENTAL STRAIN
Resolution: 2.47 Å
EM Method: Single-particle
Fitted PDBs: 8ova
Q-score: 0.63
Rajan KS, Madmoni H, Bashan A, Taoka M, Aryal S, Nobe Y, Doniger T, Galili Kostin B, Blumberg A, Cohen-Chalamish S, Schwartz S, Rivalta A, Zimmerman E, Unger R, Isobe T, Yonath A, Michaeli S
Nat Commun (2023) 14 pp. 7462-7462 [ DOI: doi:10.1038/s41467-023-43263-6 Pubmed: 37985661 ]
- 40s ribosomal protein s26 (12 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s2, putative (28 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l32, putative (15 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein s10 (13 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l44 (12 kDa, Protein from Trypanosoma brucei brucei)
- 5.8s rrna (67 kDa, RNA from Trypanosoma brucei brucei)
- 60s ribosomal protein l10, putative (24 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s10, putative (19 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein l14, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l5, putative (34 kDa, Protein from Trypanosoma brucei brucei)
- Rna-binding protein (30 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal subunit protein l31, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s21, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l9, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l19, putative (29 kDa, Protein from Trypanosoma brucei brucei)
- E-site trna (6 kDa, RNA from Trypanosoma brucei brucei)
- 40s ribosomal protein s27, putative (9 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s6 (28 kDa, Protein from Trypanosoma brucei brucei)
- Lsua rrna (619 kDa, RNA from Trypanosoma brucei brucei)
- 40s ribosomal protein s18, putative (17 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l23a (18 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s14 (15 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s15a, putative (14 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein s19, putative (18 kDa, Protein from Trypanosoma brucei brucei)
- Sodium ion (22 Da, Ligand)
- 60s ribosomal protein l28, putative (16 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s8 (25 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l35a, putative (17 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal proteins s11, putative (20 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s25 (12 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l39, putative (6 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein sa (31 kDa, Protein from Trypanosoma brucei brucei)
- Srrna-1 (69 kDa, RNA from Trypanosoma brucei brucei)
- 40s ribosomal protein s3a (29 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l30 (11 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s5, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s30 (7 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s15, putative (17 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein l3, mitochondrial, putative (48 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l29 (8 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l35, putative (15 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l13 (25 kDa, Protein from Trypanosoma brucei brucei)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s23, putative (15 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s4 (30 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l4 (41 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein l41 (4 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein l15 (26 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l7, putative (29 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l11, putative (22 kDa, Protein from Trypanosoma brucei brucei)
- Srrna-2 (59 kDa, RNA from Trypanosoma brucei brucei)
- 60s ribosomal protein l22, putative (15 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l13a, putative (25 kDa, Protein from Trypanosoma brucei brucei)
- Srrna-4 (43 kDa, RNA from Trypanosoma brucei brucei)
- Water (18 Da, Ligand)
- 60s ribosomal protein l21e, putative (18 kDa, Protein from Trypanosoma brucei brucei)
- Zinc ion (65 Da, Ligand)
- Us14 (6 kDa, Protein from Trypanosoma brucei brucei)
- 5s rrna (38 kDa, RNA from Trypanosoma brucei brucei)
- 40s ribosomal protein s16, putative (17 kDa, Protein from Trypanosoma brucei brucei)
- Ubiquitin-60s ribosomal protein l40 (16 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l37a, putative (10 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l24, putative (14 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l6, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein l36, putative (12 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s24 (15 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l27a (16 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s13, putative (17 kDa, Protein from Trypanosoma brucei brucei)
- Probable 40s ribosomal protein s9 (22 kDa, Protein from Trypanosoma brucei brucei)
- Cryo-em structure of trypanosoma brucei procyclic form 80s ribosome : parental strain (Complex from Trypanosoma brucei brucei)
- 40s ribosomal protein s3, putative (24 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l26, putative (16 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s17, putative (16 kDa, Protein from Trypanosoma brucei brucei)
- Potassium ion (39 Da, Ligand)
- 60s ribosomal protein l2, putative (28 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s12 (15 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l34, putative (19 kDa, Protein from Trypanosoma brucei brucei)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l38, putative (9 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l17, putative (19 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s33, putative (11 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l18a (20 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein l37 (10 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l18 (21 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s7 (23 kDa, Protein from Trypanosoma brucei brucei)
- Ssu rrna (734 kDa, RNA from Trypanosoma brucei brucei)
- 60s ribosomal protein l27 (15 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l7a (30 kDa, Protein from Trypanosoma brucei brucei)
- Srrna-6 (24 kDa, RNA from Trypanosoma brucei brucei)
- Lsub rrna (494 kDa, RNA from Trypanosoma brucei brucei)
- 60s ribosomal protein l23, putative (14 kDa, Protein from Trypanosoma brucei brucei)
CRYO-EM STRUCTURE OF TRYPANOSOMA BRUCEI PROCYCLIC FORM 80S RIBOSOME : TB11CS6H1 snoRNA mutant
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8ove
Q-score: 0.605
Rajan KS, Madmoni H, Bashan A, Taoka M, Aryal S, Nobe Y, Doniger T, Galili Kostin B, Blumberg A, Cohen-Chalamish S, Schwartz S, Rivalta A, Zimmerman E, Unger R, Isobe T, Yonath A, Michaeli S
Nat Commun (2023) 14 pp. 7462-7462 [ DOI: doi:10.1038/s41467-023-43263-6 Pubmed: 37985661 ]
- Ribosomal protein s19, putative (18 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l34, putative (19 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s27, putative (9 kDa, Protein from Trypanosoma brucei brucei)
- 80s ribosome (Complex from Trypanosoma brucei brucei)
- 40s ribosomal protein s21, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l23, putative (14 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l30 (11 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s6 (28 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s15a, putative (14 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l35a, putative (17 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l19, putative (29 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein l14, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l29 (8 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l5, putative (34 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s4 (30 kDa, Protein from Trypanosoma brucei brucei)
- Lsub rrna (494 kDa, RNA from Trypanosoma brucei brucei)
- Ribosomal protein s10 (13 kDa, Protein from Trypanosoma brucei brucei)
- Srrna 6 (24 kDa, RNA from Trypanosoma brucei brucei)
- 60s ribosomal protein l27a (16 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s10, putative (19 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein l36, putative (12 kDa, Protein from Trypanosoma brucei brucei)
- E-site trna (6 kDa, RNA from Trypanosoma brucei brucei)
- 40s ribosomal protein s3a (29 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s3, putative (24 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l7a (30 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l38, putative (9 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s13, putative (17 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l11, putative (22 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal proteins s11, putative (20 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s24 (15 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l10, putative (24 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s17, putative (16 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s2, putative (28 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s18, putative (17 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l28, putative (16 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l32, putative (15 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s33, putative (11 kDa, Protein from Trypanosoma brucei brucei)
- Sodium ion (22 Da, Ligand)
- 60s ribosomal protein l9, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein l37 (10 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal subunit protein l31, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l18a (20 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l21e, putative (18 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l26, putative (16 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l39, putative (6 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l6, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- Water (18 Da, Ligand)
- Putative ribosomal protein s29 (6 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s30 (7 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s26 (12 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l17, putative (19 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l27 (15 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein l41 (4 kDa, Protein from Trypanosoma brucei brucei)
- 5s rrna (38 kDa, RNA from Trypanosoma brucei brucei)
- Ribosomal protein l15 (26 kDa, Protein from Trypanosoma brucei brucei)
- 5.8s rrna (67 kDa, RNA from Trypanosoma brucei brucei)
- Srrna 4 (43 kDa, RNA from Trypanosoma brucei brucei)
- 60s ribosomal protein l22, putative (15 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l44 (12 kDa, Protein from Trypanosoma brucei brucei)
- His-thr-cys-thr (461 Da, Protein from Trypanosoma brucei brucei)
- Ribosomal protein l3, mitochondrial, putative (48 kDa, Protein from Trypanosoma brucei brucei)
- Ribosomal protein l24 (14 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s23, putative (15 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l13a, putative (25 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s16, putative (17 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s14 (15 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s25 (12 kDa, Protein from Trypanosoma brucei brucei)
- Ssu rrna (734 kDa, RNA from Trypanosoma brucei brucei)
- Rna-binding protein (30 kDa, Protein from Trypanosoma brucei brucei)
- Magnesium ion (24 Da, Ligand)
- Srrna 2 (59 kDa, RNA from Trypanosoma brucei brucei)
- 60s ribosomal protein l35, putative (15 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l13 (25 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l23a (18 kDa, Protein from Trypanosoma brucei brucei)
- Potassium ion (39 Da, Ligand)
- Lus_alpha rrna (619 kDa, RNA from Trypanosoma brucei brucei)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s8 (25 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein sa (31 kDa, Protein from Trypanosoma brucei brucei)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Trypanosoma brucei brucei)
- Probable 40s ribosomal protein s9 (22 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l4 (41 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s7 (23 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s15, putative (17 kDa, Protein from Trypanosoma brucei brucei)
- 40s ribosomal protein s5, putative (21 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l18 (21 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l2, putative (28 kDa, Protein from Trypanosoma brucei brucei)
- 60s ribosomal protein l7, putative (29 kDa, Protein from Trypanosoma brucei brucei)
- Srrna 1 (69 kDa, RNA from Trypanosoma brucei brucei)
- 60s ribosomal protein l37a, putative (10 kDa, Protein from Trypanosoma brucei brucei)
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT
Resolution: 2.46 Å
EM Method: Single-particle
Fitted PDBs: 8a98
Q-score: 0.653
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ DOI: doi:10.1016/j.celrep.2024.114203 Pubmed: 38722744 ]
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Cryo-em structure of leishmania major 80s ribosome snorna mutant (Complex from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (6 kDa, RNA from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- Small ribosomal subunit protein rack1 (34 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- El13_chain_i (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s11 (20 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
Cryo-EM structure of the plant 80S ribosome
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8b2l
Q-score: 0.639
Smirnova J, Loerke J, Kleinau G, Schmidt A, Burger J, Meyer EH, Mielke T, Scheerer P, Bock R, Spahn CMT, Zoschke R
Nat Plants (2023) 9 pp. 987-1000 [ DOI: doi:10.1038/s41477-023-01407-y Pubmed: 37156858 ]
- 40s ribosomal protein s26 (14 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s25 (11 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l41 (3 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l7a (29 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l34 (13 kDa, Protein from Nicotiana tabacum)
- El31 (60s ribosomal protein l31) (13 kDa, Protein from Nicotiana tabacum)
- El28 (60s ribosomal protein l28) (15 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l39-3 (6 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s24 (15 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s5-like (23 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s9-2-like (23 kDa, Protein from Nicotiana tabacum)
- Ribosomal protein l15 (24 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s27 (9 kDa, Protein from Nicotiana tabacum)
- 50s ribosomal protein l22, chloroplastic (20 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s3a (29 kDa, Protein from Nicotiana tabacum)
- 5s rrna (38 kDa, RNA from Nicotiana tabacum)
- 40s ribosomal protein s16 (16 kDa, Protein from Nicotiana tabacum)
- 18s rrna (583 kDa, RNA from Nicotiana tabacum)
- Ul16 (60s ribosomal protein l10) (25 kDa, Protein from Nicotiana tabacum)
- El6 (60s ribosomal protein l6) (25 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s3-2-like (27 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l13 (23 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s15-like (17 kDa, Protein from Nicotiana tabacum)
- Ul5 (60s ribosomal protein l11) (20 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l38 (8 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l14-1 (15 kDa, Protein from Nicotiana tabacum)
- Ul15 (60s ribosomal protein l27a) (16 kDa, Protein from Nicotiana tabacum)
- Spermine (202 Da, Ligand)
- 40s ribosomal protein s4 (29 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s6 (28 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l44 (12 kDa, Protein from Nicotiana tabacum)
- Zinc ion (65 Da, Ligand)
- Spermidine (145 Da, Ligand)
- 40s ribosomal protein s8 (25 kDa, Protein from Nicotiana tabacum)
- Nascent chain (2 kDa, Protein from Nicotiana tabacum)
- Ribosomal protein l19 (25 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l32-1 (15 kDa, Protein from Nicotiana tabacum)
- El36 (60s ribosomal protein l36) (12 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l24-like (18 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l23a (17 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s20-2 (13 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein sa (35 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s10-1-like (23 kDa, Protein from Nicotiana tabacum)
- Ul2 (60s ribosomal protein l8) (28 kDa, Protein from Nicotiana tabacum)
- Ubiquitin-40s ribosomal protein s27a-like (17 kDa, Protein from Nicotiana tabacum)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l23 (15 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s23 (15 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s28 (7 kDa, Protein from Nicotiana tabacum)
- 25s rrna (1 MDa, RNA from Nicotiana tabacum)
- 40s ribosomal protein s21 (9 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l37a (10 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l29 (7 kDa, Protein from Nicotiana tabacum)
- Water (18 Da, Ligand)
- 60s ribosomal protein l5-like (34 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l30-like (12 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l18-2-like (20 kDa, Protein from Nicotiana tabacum)
- Ul24 (60s ribosomal protein l26) (16 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s30 (6 kDa, Protein from Nicotiana tabacum)
- Guanine nucleotide-binding protein subunit beta-like protein (36 kDa, Protein from Nicotiana tabacum)
- Ul4 (60s ribosomal protein l4) (44 kDa, Protein from Nicotiana tabacum)
- Ul13 (60s ribosomal protein l13a) (23 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l7-4-like (28 kDa, Protein from Nicotiana tabacum)
- Magnesium ion (24 Da, Ligand)
- El33 (60s ribosomal protein l35a) (12 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l18a (21 kDa, Protein from Nicotiana tabacum)
- 30s ribosomal protein s15, chloroplastic (17 kDa, Protein from Nicotiana tabacum)
- Potassium ion (39 Da, Ligand)
- Trna (24 kDa, RNA from Nicotiana tabacum)
- Ul3 (60s ribosomal protein l3) (44 kDa, Protein from Nicotiana tabacum)
- 40s subunit of the cytosolic 80s ribosome from tobacco (Complex from Nicotiana tabacum)
- 40s ribosomal protein s11-like (17 kDa, Protein from Nicotiana tabacum)
- Mrna (3 kDa, RNA from Nicotiana tabacum)
- 60s ribosomal protein l22-2-like (14 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s18 (17 kDa, Protein from Nicotiana tabacum)
- Ul6 (60s ribosomal protein l9) (22 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s19-3 (16 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l21-1-like (18 kDa, Protein from Nicotiana tabacum)
- Ribosomal protein l37 (10 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s14-2 (16 kDa, Protein from Nicotiana tabacum)
- 60s ribosomal protein l35-like (14 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s29 (6 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s2-3-like (30 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s12 (15 kDa, Protein from Nicotiana tabacum)
- 5.8s rrna (52 kDa, RNA from Nicotiana tabacum)
- 40s ribosomal protein s15a-1 (14 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s17-like (16 kDa, Protein from Nicotiana tabacum)
- El27 (60s ribosomal protein l27) (15 kDa, Protein from Nicotiana tabacum)
- 40s ribosomal protein s7 (22 kDa, Protein from Nicotiana tabacum)