High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7xnx
Q-score: 0.58
Zhou F, Aroua N, Liu Y, Rohde C, Cheng J, Wirth AK, Fijalkowska D, Gollner S, Lotze M, Yun H, Yu X, Pabst C, Sauer T, Oellerich T, Serve H, Rollig C, Bornhauser M, Thiede C, Baldus C, Frye M, Raffel S, Krijgsveld J, Jeremias I, Beckmann R, Trumpp A, Muller-Tidow C
Cancer Discov (2023) 13 pp. 332-347 [ Pubmed: 36259929 DOI: doi:10.1158/2159-8290.CD-22-0210 ]
- 40s ribosomal protein s28 (7 kDa, Protein from human)
- 40s ribosomal protein s24 (15 kDa, Protein from human)
- 60s ribosomal protein l21 (18 kDa, Protein from human)
- 60s ribosomal protein l19 (23 kDa, Protein from human)
- 40s ribosomal protein s8 (24 kDa, Protein from human)
- 60s ribosomal protein l38 (8 kDa, Protein from human)
- 60s ribosomal protein l22 (14 kDa, Protein from human)
- 40s ribosomal protein s17 (15 kDa, Protein from human)
- 60s ribosomal protein l7 (29 kDa, Protein from human)
- Ribosomal protein l10 isoform a (24 kDa, Protein from human)
- 40s ribosomal protein s2 (31 kDa, Protein from human)
- 40s ribosomal protein s25 (13 kDa, Protein from human)
- 40s ribosomal protein s27 (9 kDa, Protein from human)
- 40s ribosomal protein s15a (14 kDa, Protein from human)
- 40s ribosomal protein s21 (9 kDa, Protein from human)
- 60s ribosomal protein l30 (12 kDa, Protein from human)
- 60s ribosomal protein l34 (13 kDa, Protein from human)
- 28s rrna (1 MDa, RNA from human)
- 40s ribosomal protein s9 (22 kDa, Protein from human)
- 40s ribosomal protein s14 (16 kDa, Protein from human)
- 40s ribosomal protein s6 (28 kDa, Protein from human)
- Trna (24 kDa, RNA from human)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l31 (14 kDa, Protein from human)
- 60s ribosomal protein l23 (14 kDa, Protein from human)
- 40s ribosomal protein s5 (22 kDa, Protein from human)
- 60s ribosomal protein l6 (32 kDa, Protein from human)
- 60s ribosomal protein l37 (11 kDa, Protein from human)
- 60s ribosomal protein l36a (12 kDa, Protein from human)
- 60s ribosomal protein l37a (10 kDa, Protein from human)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from human)
- 40s ribosomal protein s7 (22 kDa, Protein from human)
- 40s ribosomal protein s18 (17 kDa, Protein from human)
- 60s ribosomal protein l35a (12 kDa, Protein from human)
- 60s ribosomal protein l27 (32 kDa, Protein from human)
- 40s ribosomal protein s3a (30 kDa, Protein from human)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from human)
- 40s ribosomal protein s29 (6 kDa, Protein from human)
- 40s ribosomal protein s10 (18 kDa, Protein from human)
- 60s ribosomal protein l29 (17 kDa, Protein from human)
- 60s ribosomal protein l3 (46 kDa, Protein from human)
- Ubiquitin-40s ribosomal protein s27a (15 kDa, Protein from human)
- 60s ribosomal protein l23a (17 kDa, Protein from human)
- 5.8s rrna (50 kDa, RNA from human)
- 60s ribosomal protein l39 (6 kDa, Protein from human)
- Water (18 Da, Ligand)
- 60s ribosomal protein l15 (24 kDa, Protein from human)
- 60s ribosomal protein l14 (23 kDa, Protein from human)
- 40s ribosomal protein s13 (17 kDa, Protein from human)
- 40s ribosomal protein s19 (16 kDa, Protein from human)
- 60s ribosomal protein l28 (15 kDa, Protein from human)
- 60s ribosomal protein l18 (21 kDa, Protein from human)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from human)
- 5s rrna (38 kDa, RNA from human)
- 60s ribosomal protein l41 (3 kDa, Protein from human)
- 60s ribosomal protein l26 (17 kDa, Protein from human)
- 40s ribosomal protein s26 (13 kDa, Protein from human)
- 60s ribosomal protein l24 (17 kDa, Protein from human)
- 40s ribosomal protein s12 (14 kDa, Protein from human)
- 60s ribosomal protein l9 (21 kDa, Protein from human)
- 60s ribosomal protein l8 (28 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l13 (24 kDa, Protein from human)
- 40s ribosomal protein s16 (16 kDa, Protein from human)
- 60s ribosomal protein l11 (20 kDa, Protein from human)
- Potassium ion (39 Da, Ligand)
- 40s ribosomal protein s11 (18 kDa, Protein from human)
- Ribosome (Complex from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from human)
- 40s ribosomal protein s3 (26 kDa, Protein from human)
- 40s ribosomal protein s30 (6 kDa, Protein from human)
- 60s ribosomal protein l4 (47 kDa, Protein from human)
- 60s ribosomal protein l36 (12 kDa, Protein from human)
- 40s ribosomal protein sa (32 kDa, Protein from human)
- 40s ribosomal protein s15 (17 kDa, Protein from human)
- 40s ribosomal protein s23 (15 kDa, Protein from human)
- 60s ribosomal protein l13a (23 kDa, Protein from human)
- 60s ribosomal protein l7a (30 kDa, Protein from human)
- 60s ribosomal protein l32 (15 kDa, Protein from human)
- 18s rrna (603 kDa, RNA from human)
- 60s ribosomal protein l18a (20 kDa, Protein from human)
- 40s ribosomal protein s20 (13 kDa, Protein from human)
- 60s ribosomal protein l5 (34 kDa, Protein from human)
- 60s ribosomal protein l35 (14 kDa, Protein from human)
High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7xny
Q-score: 0.56
Zhou F, Aroua N, Liu Y, Rohde C, Cheng J, Wirth AK, Fijalkowska D, Gollner S, Lotze M, Yun H, Yu X, Pabst C, Sauer T, Oellerich T, Serve H, Rollig C, Bornhauser M, Thiede C, Baldus C, Frye M, Raffel S, Krijgsveld J, Jeremias I, Beckmann R, Trumpp A, Muller-Tidow C
Cancer Discov (2023) 13 pp. 332-347 [ Pubmed: 36259929 DOI: doi:10.1158/2159-8290.CD-22-0210 ]
- 40s ribosomal protein s28 (7 kDa, Protein from human)
- 40s ribosomal protein s24 (15 kDa, Protein from human)
- 60s ribosomal protein l21 (18 kDa, Protein from human)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from human)
- 60s ribosomal protein l19 (23 kDa, Protein from human)
- 40s ribosomal protein s8 (24 kDa, Protein from human)
- 60s ribosomal protein l38 (8 kDa, Protein from human)
- 60s ribosomal protein l22 (14 kDa, Protein from human)
- 40s ribosomal protein s17 (15 kDa, Protein from human)
- 60s ribosomal protein l7 (29 kDa, Protein from human)
- Ribosomal protein l10 isoform a (24 kDa, Protein from human)
- 40s ribosomal protein s2 (31 kDa, Protein from human)
- 40s ribosomal protein s25 (13 kDa, Protein from human)
- 40s ribosomal protein s27 (9 kDa, Protein from human)
- 40s ribosomal protein s15a (14 kDa, Protein from human)
- 40s ribosomal protein s21 (9 kDa, Protein from human)
- 60s ribosomal protein l30 (12 kDa, Protein from human)
- 60s ribosomal protein l34 (13 kDa, Protein from human)
- 28s rrna (1 MDa, RNA from human)
- 40s ribosomal protein s9 (22 kDa, Protein from human)
- 40s ribosomal protein s14 (16 kDa, Protein from human)
- 5.8s rrna (50 kDa, RNA from human)
- 40s ribosomal protein s6 (28 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 18s rrna (603 kDa, RNA from human)
- 60s ribosomal protein l31 (14 kDa, Protein from human)
- 60s ribosomal protein l23 (14 kDa, Protein from human)
- 40s ribosomal protein s5 (22 kDa, Protein from human)
- 60s ribosomal protein l6 (32 kDa, Protein from human)
- 60s ribosomal protein l37 (11 kDa, Protein from human)
- 60s ribosomal protein l36a (12 kDa, Protein from human)
- 60s ribosomal protein l37a (10 kDa, Protein from human)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from human)
- 60s ribosomal protein l27 (15 kDa, Protein from human)
- 40s ribosomal protein s7 (22 kDa, Protein from human)
- 40s ribosomal protein s18 (17 kDa, Protein from human)
- 60s ribosomal protein l35a (12 kDa, Protein from human)
- 40s ribosomal protein s3a (30 kDa, Protein from human)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from human)
- 40s ribosomal protein s29 (6 kDa, Protein from human)
- 40s ribosomal protein s10 (18 kDa, Protein from human)
- 60s ribosomal protein l29 (17 kDa, Protein from human)
- 60s ribosomal protein l3 (46 kDa, Protein from human)
- 60s ribosomal protein l23a (17 kDa, Protein from human)
- 60s ribosomal protein l39 (6 kDa, Protein from human)
- 5s rrna (38 kDa, RNA from human)
- Water (18 Da, Ligand)
- 60s ribosomal protein l15 (24 kDa, Protein from human)
- 60s ribosomal protein l14 (23 kDa, Protein from human)
- 40s ribosomal protein s13 (17 kDa, Protein from human)
- 40s ribosomal protein s19 (16 kDa, Protein from human)
- 60s ribosomal protein l28 (15 kDa, Protein from human)
- 60s ribosomal protein l18 (21 kDa, Protein from human)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from human)
- 60s ribosomal protein l41 (3 kDa, Protein from human)
- 60s ribosomal protein l26 (17 kDa, Protein from human)
- 40s ribosomal protein s26 (13 kDa, Protein from human)
- 60s ribosomal protein l24 (17 kDa, Protein from human)
- 40s ribosomal protein s12 (14 kDa, Protein from human)
- 60s ribosomal protein l9 (21 kDa, Protein from human)
- 60s ribosomal protein l8 (28 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l13 (24 kDa, Protein from human)
- 40s ribosomal protein s16 (16 kDa, Protein from human)
- 60s ribosomal protein l11 (20 kDa, Protein from human)
- Potassium ion (39 Da, Ligand)
- 40s ribosomal protein s11 (18 kDa, Protein from human)
- Ribosome (Complex from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from human)
- 40s ribosomal protein s3 (26 kDa, Protein from human)
- 40s ribosomal protein s30 (6 kDa, Protein from human)
- 60s ribosomal protein l4 (47 kDa, Protein from human)
- 60s ribosomal protein l36 (12 kDa, Protein from human)
- 40s ribosomal protein sa (32 kDa, Protein from human)
- 40s ribosomal protein s15 (17 kDa, Protein from human)
- 40s ribosomal protein s23 (15 kDa, Protein from human)
- 60s ribosomal protein l13a (23 kDa, Protein from human)
- 60s ribosomal protein l27a (16 kDa, Protein from human)
- 60s ribosomal protein l7a (30 kDa, Protein from human)
- 60s ribosomal protein l32 (15 kDa, Protein from human)
- 60s ribosomal protein l18a (20 kDa, Protein from human)
- 40s ribosomal protein s20 (13 kDa, Protein from human)
- 60s ribosomal protein l5 (34 kDa, Protein from human)
- 60s ribosomal protein l35 (14 kDa, Protein from human)