AP-3 bound to myristoylated Arf1 (Q71L)
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 9c58
Q-score: 0.238
To Be Published
- Ap-3 complex subunit mu-1 (46 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Adp-ribosylation factor 1 (20 kDa, Protein from Homo sapiens)
- Ap-3 complex subunit sigma-1 (21 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Ap-3 bound to myristoylated arf1 (q71l) (240 kDa, Complex from Homo sapiens)
- Ap-3 complex subunit delta-1 (69 kDa, Protein from Homo sapiens)
- Ap-3 complex subunit beta-1 (76 kDa, Protein from Homo sapiens)
Human AP-3 dimer bound to myristoylated Arf1 (Q71L) and LAMP1 cargo on a lipid nanodisc
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 9c59
Q-score: 0.156
To Be Published
- Ap-3 complex subunit mu-1 (46 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Adp-ribosylation factor 1 (20 kDa, Protein from Homo sapiens)
- Ap-3 complex subunit sigma-1 (21 kDa, Protein from Homo sapiens)
- Lysosome-associated membrane glycoprotein 1 (1 kDa, Protein from Homo sapiens)
- Human ap-3 dimer bound to myristoylated arf1 (q71l) and lamp1 cargo on a lipid nanodisc (600 kDa, Complex from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Ap-3 complex subunit delta-1 (69 kDa, Protein from Homo sapiens)
- Ap-3 complex subunit beta-1 (76 kDa, Protein from Homo sapiens)
AP-3 Arf1 dimeric interface, focused refinement
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 9c5a
Q-score: 0.233
To Be Published
- Ap-3 complex subunit mu-1 (46 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Adp-ribosylation factor 1 (20 kDa, Protein from Homo sapiens)
- Lysosome-associated membrane glycoprotein 1 (1 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Ap-3 complex subunit beta-1 (77 kDa, Protein from Homo sapiens)
- Ap-3 arf1 dimeric interface, focused refinement (256 kDa, Complex)
AP-3 bound to myristoylated Arf1 (Q71L) and LAMPI on a lipid nanodisc; combined map
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 9c5b
Q-score: 0.18
To Be Published
- Ap-3 complex subunit delta-1 (69 kDa, Protein from Homo sapiens)
- Ap-3 complex subunit sigma-1 (21 kDa, Protein from Homo sapiens)
- Ap-3 complex subunit beta-1 (76 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Lysosome-associated membrane glycoprotein 1 (1 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Ap-3 bound to myristoylated arf1 (q71l) and lampi on a lipid nanodisc; combined map (215 kDa, Complex)
- Adp-ribosylation factor 1 (20 kDa, Protein from Homo sapiens)
- Ap-3 complex subunit mu-1 (46 kDa, Protein from Homo sapiens)
Structure of Human Adaptor Protein Complex AP-3 in the Apo State
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9c5c
Q-score: 0.211
To Be Published
- Ap-3 complex subunit delta-1 (66 kDa, Protein from Homo sapiens)
- Human adaptor protein complex ap-3 in the apo state (215 kDa, Complex from Homo sapiens)
- Ap-3 complex subunit mu-1 (14 kDa, Protein from Homo sapiens)
- Ap-3 complex subunit beta-1 (65 kDa, Protein from Homo sapiens)
- Ap-3 complex subunit sigma-1 (17 kDa, Protein from Homo sapiens)
Homology model of the full-length AP-3 complex in a compact open conformation
Resolution: 9.1 Å
EM Method: Single-particle
Fitted PDBs: 7p3x
Q-score: 0.085
Schoppe J, Schubert E, Apelbaum A, Yavavli E, Birkholz O, Stephanowitz H, Han Y, Perz A, Hofnagel O, Liu F, Piehler J, Raunser S, Ungermann C
J Biol Chem (2021) 297 pp. 101334-101334 [ Pubmed: 34688652 DOI: doi:10.1016/j.jbc.2021.101334 ]
- Ap-3 complex subunit delta (110 kDa, Protein from Saccharomyces cerevisiae)
- Full-length ap-3 complex from saccharomyces cerevisiae (Complex from Saccharomyces cerevisiae)
- Ap complex subunit sigma (21 kDa, Protein from Saccharomyces cerevisiae)
- Ap-3 complex subunit mu (54 kDa, Protein from Saccharomyces cerevisiae)
- Y55_g0035830.mrna.1.cds.1 (91 kDa, Protein from Saccharomyces cerevisiae)
Homology model of the full-length AP-3 complex in an intermediate open conformation
Resolution: 10.1 Å
EM Method: Single-particle
Fitted PDBs: 7p3y
Q-score: 0.093
Schoppe J, Schubert E, Apelbaum A, Yavavli E, Birkholz O, Stephanowitz H, Han Y, Perz A, Hofnagel O, Liu F, Piehler J, Raunser S, Ungermann C
J Biol Chem (2021) 297 pp. 101334-101334 [ Pubmed: 34688652 DOI: doi:10.1016/j.jbc.2021.101334 ]
- Ap-3 complex subunit delta (110 kDa, Protein from Saccharomyces cerevisiae)
- Full-length ap-3 complex from saccharomyces cerevisiae (Complex from Saccharomyces cerevisiae)
- Ap complex subunit sigma (21 kDa, Protein from Saccharomyces cerevisiae)
- Ap-3 complex subunit mu (54 kDa, Protein from Saccharomyces cerevisiae)
- Y55_g0035830.mrna.1.cds.1 (91 kDa, Protein from Saccharomyces cerevisiae)
Homology model of the full-length AP-3 complex in a stretched open conformation
Resolution: 10.5 Å
EM Method: Single-particle
Fitted PDBs: 7p3z
Q-score: 0.089
Schoppe J, Schubert E, Apelbaum A, Yavavli E, Birkholz O, Stephanowitz H, Han Y, Perz A, Hofnagel O, Liu F, Piehler J, Raunser S, Ungermann C
J Biol Chem (2021) 297 pp. 101334-101334 [ Pubmed: 34688652 DOI: doi:10.1016/j.jbc.2021.101334 ]
- Ap-3 complex subunit delta (110 kDa, Protein from Saccharomyces cerevisiae)
- Full-length ap-3 complex from saccharomyces cerevisiae (Complex from Saccharomyces cerevisiae)
- Ap complex subunit sigma (21 kDa, Protein from Saccharomyces cerevisiae)
- Ap-3 complex subunit mu (54 kDa, Protein from Saccharomyces cerevisiae)
- Y55_g0035830.mrna.1.cds.1 (91 kDa, Protein from Saccharomyces cerevisiae)