The F1 region of ammocidin-bound Saccharomyces cerevisiae ATP synthase
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7md2
Q-score: 0.52
Reisman BJ, Guo H, Ramsey HE, Wright MT, Reinfeld BI, Ferrell PB, Sulikowski GA, Rathmell WK, Savona MR, Plate L, Rubinstein JL, Bachmann BO
bioRxiv (2021) [ DOI: doi:10.1101/2021.05.31.445492 ]
- Atp synthase subunit epsilon, mitochondrial (6 kDa, Protein from Saccharomyces cerevisiae)
- (3~{e},5~{z},7~{e},9~{r},10~{s},11~{e},13~{e},15~{e},17~{r},18~{s},20~{s})-20-[(1~{r})-1-[(2~{s},3~{r},4~{r},5~{s},6~{r})-5-[(2~{s},4~{s},5~{s},6~{r})-5-[(2~{s},4~{r},5~{r},6~{r})-4,6-dimethyl-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-methyl-4-oxidanyl-oxan-2-yl]oxy-3-methoxy-6-(3-methoxypropyl)-5-methyl-2,4-bis(oxidanyl)oxan-2-yl]ethyl]-5,18-dimethoxy-3,7,9,11,13,15-hexamethyl-10-[(2~{r},3~{s},4~{r},5~{r},6~{s})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-17-oxidanyl-1-oxacycloicosa-3,5,7,11,13,15-hexaen-2-one (1 kDa, Ligand)
- Atp synthase subunit gamma (30 kDa, Protein from Saccharomyces cerevisiae)
- Atp synthase subunit alpha (55 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Atp synthase subunit beta (51 kDa, Protein from Saccharomyces cerevisiae)
- The f1 region of ammocidin-bound saccharomyces cerevisiae atp synthase (400 kDa, Complex from Saccharomyces cerevisiae)
The F1 region of apoptolidin-bound Saccharomyces cerevisiae ATP synthase
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7md3
Q-score: 0.46
Reisman BJ, Guo H, Ramsey HE, Wright MT, Reinfeld BI, Ferrell PB, Sulikowski GA, Rathmell WK, Savona MR, Plate L, Rubinstein JL, Bachmann BO
bioRxiv (2021) [ DOI: doi:10.1101/2021.05.31.445492 ]
- Phosphate ion (94 Da, Ligand)
- Atp synthase subunit beta (51 kDa, Protein from Saccharomyces cerevisiae)
- Atp synthase subunit alpha (55 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Atp synthase subunit gamma (30 kDa, Protein from Saccharomyces cerevisiae)
- Atp synthase subunit epsilon, mitochondrial (6 kDa, Protein from Saccharomyces cerevisiae)
- The f1 region of apoptolidin-bound saccharomyces cerevisiae atp synthase (400 kDa, Complex from Saccharomyces cerevisiae)
- (3~{e},5~{e},7~{e},9~{r},10~{r},11~{e},13~{e},17~{s},18~{s},20~{s})-18-methoxy-20-[(~{r})-[(2~{r},3~{r},4~{s},5~{r},6~{r})-6-[(2~{r})-3-methoxy-2-[(2~{r},4~{s},5~{s},6~{s})-5-[(2~{s},4~{r},5~{r},6~{r})-4-methoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-4,6-dimethyl-4-oxidanyl-oxan-2-yl]oxy-propyl]-3,5-dimethyl-2,4-bis(oxidanyl)oxan-2-yl]-oxidanyl-methyl]-10-[(2~{r},3~{s},4~{s},5~{r},6~{s})-5-methoxy-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-3,5,7,9,13-pentamethyl-17-oxidanyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one (1 kDa, Ligand)