Actin 1 from T. gondii in filaments bound to MgADP and jasplakinolide
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8trn
Q-score: 0.575
Hvorecny KL, Sladewski TE, De La Cruz EM, Kollman JM, Heaslip AT
Nat Commun (2024) 15 pp. 1840-1840 [ Pubmed: 38418447 DOI: doi:10.1038/s41467-024-46111-3 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Jasplakinolide (709 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Filament of actin 1 from t. gondii with mgadp and jasplakinolide (Complex from Toxoplasma gondii)
- Actin (41 kDa, Protein from Toxoplasma gondii)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 8d17
Q-score: 0.518
Reynolds MJ, Hachicho C, Carl AG, Gong R, Alushin GM
Nature (2022) 611 pp. 380-386 [ Pubmed: 36289330 DOI: doi:10.1038/s41586-022-05366-w ]
- Straight f-actin 1, adp nucleotide state (15 MDa, Complex from Gallus gallus)
- Magnesium ion (24 Da, Ligand)
- Actin, alpha skeletal muscle (42 kDa, Protein from chicken)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Resolution: 3.77 Å
EM Method: Helical reconstruction
Fitted PDBs: 7aln
Q-score: 0.402
Robert-Paganin J, Xu XP, Swift MF, Auguin D, Robblee JP, Lu H, Fagnant PM, Krementsova EB, Trybus KM, Houdusse A, Volkmann N, Hanein D
Nat Commun (2021) 12 pp. 1892-1892 [ Pubmed: 33767187 DOI: doi:10.1038/s41467-021-22093-4 ]
- Actomyosin complex from plasmodium falciparum (Complex from Plasmodium falciparum (isolate 3D7))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Myosin-a (92 kDa, Protein from Plasmodium falciparum (isolate 3D7))
- Jasplakinolide (709 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Actin-1 (41 kDa, Protein from Plasmodium falciparum (isolate 3D7))
Structure of PfMyoA decorated Plasmodium Act1 filament
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 6tu7
Q-score: 0.55
Vahokoski J, Calder LJ, Lopez AJ, Molloy JE, Kursula I, Rosenthal PB
PLoS Pathog (2022) 18 pp. e1010408-e1010408 [ DOI: doi:10.1371/journal.ppat.1010408 Pubmed: 35377914 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin-1 (42 kDa, Protein from Plasmodium falciparum 3D7)
- Pfmyoa decorated pfact1 filament (Complex from Plasmodium falciparum 3D7)
- Myosin-a (92 kDa, Protein from Plasmodium falciparum 3D7)
- Magnesium ion (24 Da, Ligand)
- Jasplakinolide (709 Da, Ligand)
Cryo-EM structure of jasplakinolide-stabilized malaria parasite F-actin at near-atomic resolution
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 5ogw
Q-score: 0.424
Pospich S, Kumpula EP, von der Ecken J, Vahokoski J, Kursula I, Raunser S
PNAS (2017) 114 pp. 10636-10641 [ DOI: doi:10.1073/pnas.1707506114 Pubmed: 28923924 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin-1 (42 kDa, Protein from Plasmodium falciparum (isolate HB3))
- Plasmodium falciparum actin 1 filament stabilized by jasplakinolide (Complex from Plasmodium falciparum HB3)
- Jasplakinolide (709 Da, Ligand)
- Magnesium ion (24 Da, Ligand)