beta/alpha1 region of ApoB 100
Reimund M, Dearborn AD, Graziano G, Lei H, Ciancone AM, Kumar A, Holewinski R, Neufeld EB, O'Reilly FJ, Remaley AT, Marcotrigiano J
Nature (2025) 638 pp. 829-835 [ Pubmed: 39663455 DOI: doi:10.1038/s41586-024-08223-0 ]
- Apolipoprotein b-100 (516 kDa, Protein from Homo sapiens)
- Legobody mbp/igg-binding protein a/igg-binding protein g fusion (Complex from Escherichia coli)
- Apolipoprotein b 100 on ldl with ldl receptor and legobody (Complex)
- Low density lipoprotein apob 100 (Complex from Homo sapiens)
- Ldl receptor (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Legobody fab (Complex from Mus musculus)
ApoB 100 beta barrel bound to LDLR beta propeller
Reimund M, Dearborn AD, Graziano G, Lei H, Ciancone AM, Kumar A, Holewinski R, Neufeld EB, O'Reilly FJ, Remaley AT, Marcotrigiano J
Nature (2025) 638 pp. 829-835 [ Pubmed: 39663455 DOI: doi:10.1038/s41586-024-08223-0 ]
- Apolipoprotein b-100 (516 kDa, Protein from Homo sapiens)
- Apob100 (Complex from Homo sapiens)
- Legobody mbp/igg-binding protein a/igg-binding protein g fusion (Complex from Escherichia coli)
- Ldl apob100 bound to ldlr (Complex)
- Ldlr (Complex from Homo sapiens)
- Low-density lipoprotein receptor (95 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Legobody fab (Complex from Mus musculus)
Middle Region of Apolipoprotein B 100 bound to Low Density Lipoprotein Receptor
Reimund M, Dearborn AD, Graziano G, Lei H, Ciancone AM, Kumar A, Holewinski R, Neufeld EB, O'Reilly FJ, Remaley AT, Marcotrigiano J
Nature (2025) 638 pp. 829-835 [ Pubmed: 39663455 DOI: doi:10.1038/s41586-024-08223-0 ]
- Apolipoprotein b 100 (516 kDa, Protein from Homo sapiens)
- Middle of apob100 bound to ldl receptor and legobody (Complex)
- Maltose/maltodextrin-binding periplasmic protein,immunoglobulin g-binding protein a,immunoglobulin g-binding protein g (59 kDa, Protein from Streptococcus sp. 'group G')
- Calcium ion (40 Da, Ligand)
- Apob100 nanobody 4 (14 kDa, Protein from Camelus bactrianus)
- Legobody 8d3 fab light chain (24 kDa, Protein from Mus musculus)
- Low-density lipoprotein receptor (95 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Legobody 8d3 fab heavy chain (25 kDa, Protein from Mus musculus)
Apolipoprotein B 100 bound to LDL receptor and legobody
Reimund M, Dearborn AD, Graziano G, Lei H, Ciancone AM, Kumar A, Holewinski R, Neufeld EB, O'Reilly FJ, Remaley AT, Marcotrigiano J
Nature (2025) 638 pp. 829-835 [ Pubmed: 39663455 DOI: doi:10.1038/s41586-024-08223-0 ]
- Maltodextrin-binding protein,immunoglobulin g-binding protein a,immunoglobulin g-binding protein g (59 kDa, Protein from Escherichia coli)
- Apoliprotein b 100 from ldl bound to ldl receptor and legobody (Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Apolipoprotein b-100 (516 kDa, Protein from Homo sapiens)
- Legobody 8d3 fab light chain (24 kDa, Protein from Mus musculus)
- Apob100 nanobody 4 (14 kDa, Protein from Camelus bactrianus)
- Low-density lipoprotein receptor (95 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Legobody 8d3 fab heavy chain (25 kDa, Protein from Mus musculus)
Nanobody 4 bound to Apolipoprotein B 100
Reimund M, Dearborn AD, Graziano G, Lei H, Ciancone AM, Kumar A, Holewinski R, Neufeld EB, O'Reilly FJ, Remaley AT, Marcotrigiano J
Nature (2025) 638 pp. 829-835 [ Pubmed: 39663455 DOI: doi:10.1038/s41586-024-08223-0 ]
- Maltodextrin-binding protein,immunoglobulin g-binding protein a,immunoglobulin g-binding protein g (59 kDa, Protein from Escherichia coli)
- Calcium ion (40 Da, Ligand)
- Legobody 8d3 fab light chain (24 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Apob100 nanobody 4 (14 kDa, Protein from Camelus bactrianus)
- Middle of apob100 bound to ldl receptor and legobody (Complex from Homo sapiens)
- Apolipoprotein b 100 (516 kDa, Protein from Homo sapiens)
- Low-density lipoprotein receptor (88 kDa, Protein from Homo sapiens)
- Legobody 8d3 fab heavy chain (25 kDa, Protein from Mus musculus)
3D reconstruction of LDL at 37C (human body temperature) using cryo-EM techniques
Kumar V, Butcher SJ, Oorni K, Engelhardt P, Heikkonen J, Kaski K, Ala-Korpela M, Kovanen PT
PLoS One (2011) 6 pp. e18841-e18841 [ Pubmed: 21573056 DOI: doi:10.1371/journal.pone.0018841 ]
- Apob-100 (Protein from Homo sapiens)
- Ldl at 37c (Sample)