Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6f1t
Q-score: 0.269
Urnavicius L, Lau CK, Elshenawy MM, Morales-Rios E, Motz C, Yildiz A, Carter AP
Nature (2018) 554 pp. 202-206 [ Pubmed: 29420470 DOI: doi:10.1038/nature25462 ]
- Bicd family-like cargo adapter 1,bicd family-like cargo adapter 1,bicd family-like cargo adapter 1,bicdr-1 (42 kDa, Protein from Mus musculus)
- Arp1 actin related protein 1 homolog a (42 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- F-actin capping protein beta subunit (30 kDa, Protein from Sus scrofa)
- Cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1,dynein heavy chain,cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1,dynein heavy chain,cytoplasmic dynein 1 heavy chain 1,cytoplasmic dynein 1 heavy chain 1 (119 kDa, Protein from Homo sapiens)
- Cytoplasmic dynein 1 intermediate chain 2 (68 kDa, Protein from Homo sapiens)
- Dynactin subunit 3 (5 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (7 kDa, Protein from Sus scrofa)
- Dynactin 6 (20 kDa, Protein from Sus scrofa)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Cryo-em map of two dynein tail domains bound to dynactin and bicdr1 (Complex)
- Dynein light chain roadblock-type 1 (10 kDa, Protein from Homo sapiens)
- Bicd family-like cargo adapter 1 (Complex from Mus musculus)
- Dynein (Complex from Homo sapiens)
- Cytoplasmic dynein 1 light intermediate chain 2 (54 kDa, Protein from Homo sapiens)
- Actin, cytoplasmic 1 (41 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (7 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (50 kDa, Protein from Sus scrofa)
- Dynactin (Complex from Sus scrofa)
- Dynactin subunit 1 (4 kDa, Protein from Sus scrofa)
- Dynactin subunit 5 (20 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (10 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (52 kDa, Protein from Sus scrofa)
- Bicd family-like cargo adapter 1,bicd family-like cargo adapter 1,bicd family-like cargo adapter 1 (42 kDa, Protein from Mus musculus)
- Capping protein (actin filament) muscle z-line, alpha 1 (33 kDa, Protein from Sus scrofa)
- Dynactin subunit 1 (4 kDa, Protein from Sus scrofa)
- Dynactin subunit 4 (22 kDa, Protein from Sus scrofa)
- Actin related protein 10 homolog (43 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (2 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (5 kDa, Protein from Sus scrofa)
N terminal region of dynein tail domains in complex with dynactin filament and BICDR-1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6f1u
Q-score: 0.374
Urnavicius L, Lau CK, Elshenawy MM, Morales-Rios E, Motz C, Yildiz A, Carter AP
Nature (2018) 554 pp. 202-206 [ Pubmed: 29420470 DOI: doi:10.1038/nature25462 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Cytoplasmic dynein 1 intermediate chain 2 (68 kDa, Protein from Homo sapiens)
- Arp1 actin related protein 1 homolog a (42 kDa, Protein from Pig)
- Bicdr1 (Complex from Mus musculus)
- Cytoplasmic dynein (Complex from Homo sapiens)
- F-actin capping protein beta subunit (30 kDa, Protein from Pig)
- Capping protein (actin filament) muscle z-line, alpha 1 (33 kDa, Protein from Pig)
- Dynactin subunit 2 (2 kDa, Protein from Pig)
- Cytoplasmic dynein 1 heavy chain 1 (136 kDa, Protein from Homo sapiens)
- Two dynein tail domains bound to dynactin and bicdr1. (Complex)
- Dynactin filament (Complex from Sus scrofa)
- Bicd family-like cargo adapter 1 (65 kDa, Protein from Mus musculus)
- Dynactin subunit 2 (5 kDa, Protein from Pig)
Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3
Resolution: 6.7 Å
EM Method: Single-particle
Fitted PDBs: 6f38
Q-score: 0.23
Urnavicius L, Lau CK, Elshenawy MM, Morales-Rios E, Motz C, Yildiz A, Carter AP
Nature (2018) 554 pp. 202-206 [ Pubmed: 29420470 DOI: doi:10.1038/nature25462 ]
- Dynactin subunit 4 (22 kDa, Protein from Sus scrofa)
- Arp1 actin related protein 1 homolog a (42 kDa, Protein from Sus scrofa)
- Cytoplasmic dynein 1 heavy chain 1 (168 kDa, Protein from Homo sapiens)
- Dynactin subunit 2 (49 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- F-actin capping protein beta subunit (30 kDa, Protein from Sus scrofa)
- Hook3 (Complex from Homo sapiens)
- Cytoplasmic dynein 1 intermediate chain 2 (68 kDa, Protein from Homo sapiens)
- Dynactin subunit 3 (5 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (52 kDa, Protein from Sus scrofa)
- Dynactin 6 (20 kDa, Protein from Sus scrofa)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Dynactin subunit 2 (7 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (5 kDa, Protein from Sus scrofa)
- Dynein light chain roadblock-type 1 (10 kDa, Protein from Homo sapiens)
- Dynein (Complex from Homo sapiens)
- Cytoplasmic dynein 1 light intermediate chain 2 (54 kDa, Protein from Homo sapiens)
- Actin, cytoplasmic 1 (41 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (7 kDa, Protein from Sus scrofa)
- Dynactin (Complex from Sus scrofa)
- Dynactin subunit 1 (4 kDa, Protein from Sus scrofa)
- Dynactin subunit 5 (20 kDa, Protein from Sus scrofa)
- Hook3 (18 kDa, Protein from Homo sapiens)
- Dynactin subunit 2 (3 kDa, Protein from Sus scrofa)
- Complex of two dynein tail domains bound to dynactin and hook3 (Complex)
- Capping protein (actin filament) muscle z-line, alpha 1 (33 kDa, Protein from Sus scrofa)
- Dynactin subunit 1 (4 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (10 kDa, Protein from Sus scrofa)
- Actin related protein 10 homolog (43 kDa, Protein from Sus scrofa)
CryoEM structure of dynactin complex at 6.3 angstrom resolution
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
Science (2015) 347 pp. 1441-1446 [ DOI: doi:10.1126/science.aaa4080 Pubmed: 25814576 ]
- Dynactin complex from pig brain (1 MDa, Sample)
- Arp1 (43 kDa, Protein from Sus scrofa domesticus)
CryoEM structure of dynactin complex with p150-glued projection
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
Science (2015) 347 pp. 1441-1446 [ DOI: doi:10.1126/science.aaa4080 Pubmed: 25814576 ]
- Actin related protein 1 (42 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 6 (27 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 4 (62 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 3 (22 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 2 (50 kDa, Protein from Sus scrofa domesticus)
- Actin related protein 11 (46 kDa, Protein from Sus scrofa domesticus)
- Dynactin complex from pig brain (1 MDa, Sample)
- Beta-actin (43 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 1 (150 kDa, Protein from Sus scrofa domesticus)
- Actin capping protein (33 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 5 (25 kDa, Protein from Sus scrofa domesticus)
CryoEM structure of dynactin complex at 4.1 angstrom resolution
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5adx
Q-score: 0.301
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
Science (2015) 347 pp. 1441-1446 [ DOI: doi:10.1126/science.aaa4080 Pubmed: 25814576 ]
- Actin related protein 1 (42 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 6 (27 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 4 (62 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 3 (22 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 2 (50 kDa, Protein from Sus scrofa domesticus)
- Actin related protein 11 (46 kDa, Protein from Sus scrofa domesticus)
- Dynactin complex from pig brain (1 MDa, Sample)
- Beta-actin (43 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 1 (150 kDa, Protein from Sus scrofa domesticus)
- Actin capping protein (33 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 5 (25 kDa, Protein from Sus scrofa domesticus)
CryoEM reconstruction of dynactin complex from pig brain at 4.0 Angstrom resolution overall
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 5adx
Q-score: 0.229
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
Science (2015) 347 pp. 1441-1446 [ DOI: doi:10.1126/science.aaa4080 Pubmed: 25814576 ]
- Actin related protein 1 (42 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 6 (27 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 4 (62 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 3 (22 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 2 (50 kDa, Protein from Sus scrofa domesticus)
- Actin related protein 11 (46 kDa, Protein from Sus scrofa domesticus)
- Dynactin complex from pig brain (1 MDa, Sample)
- Beta-actin (43 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 1 (150 kDa, Protein from Sus scrofa domesticus)
- Actin capping protein (33 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 5 (25 kDa, Protein from Sus scrofa domesticus)