The pointed end complex of dynactin bound to Hook3
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6znn
Q-score: 0.264
Lau CK, O'Reilly FJ, Santhanam B, Lacey SE, Rappsilber J, Carter AP
EMBO J (2021) 40 pp. e106164-e106164 [ Pubmed: 33734450 DOI: doi:10.15252/embj.2020106164 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Hook3 (7 kDa, Protein from Homo sapiens)
- Hook3 (Complex from Homo sapiens)
- Actin, cytoplasmic 1 (41 kDa, Protein from Sus scrofa)
- Arp11 (46 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (44 kDa, Protein from Sus scrofa)
- Dynactin subunit 4 (52 kDa, Protein from Sus scrofa)
- Putative hook3 coiled coil (5 kDa, Protein from Homo sapiens)
- Dynactin 6 (20 kDa, Protein from Sus scrofa)
- Hook3 (7 kDa, Protein from Homo sapiens)
- Dynactin (Complex from Sus scrofa)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Dynein-dynactin-hook3 complex (Complex)
- Arp1 actin related protein 1 homolog a (42 kDa, Protein from Sus scrofa)
- Dynactin subunit 5 (20 kDa, Protein from Sus scrofa)
Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3
Resolution: 6.7 Å
EM Method: Single-particle
Fitted PDBs: 6f38
Q-score: 0.23
Urnavicius L, Lau CK, Elshenawy MM, Morales-Rios E, Motz C, Yildiz A, Carter AP
Nature (2018) 554 pp. 202-206 [ Pubmed: 29420470 DOI: doi:10.1038/nature25462 ]
- Dynactin subunit 4 (22 kDa, Protein from Sus scrofa)
- Arp1 actin related protein 1 homolog a (42 kDa, Protein from Sus scrofa)
- Cytoplasmic dynein 1 heavy chain 1 (168 kDa, Protein from Homo sapiens)
- Dynactin subunit 2 (49 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- F-actin capping protein beta subunit (30 kDa, Protein from Sus scrofa)
- Hook3 (Complex from Homo sapiens)
- Cytoplasmic dynein 1 intermediate chain 2 (68 kDa, Protein from Homo sapiens)
- Dynactin subunit 3 (5 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (52 kDa, Protein from Sus scrofa)
- Dynactin 6 (20 kDa, Protein from Sus scrofa)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Dynactin subunit 2 (7 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (5 kDa, Protein from Sus scrofa)
- Dynein light chain roadblock-type 1 (10 kDa, Protein from Homo sapiens)
- Dynein (Complex from Homo sapiens)
- Cytoplasmic dynein 1 light intermediate chain 2 (54 kDa, Protein from Homo sapiens)
- Actin, cytoplasmic 1 (41 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (7 kDa, Protein from Sus scrofa)
- Dynactin (Complex from Sus scrofa)
- Dynactin subunit 1 (4 kDa, Protein from Sus scrofa)
- Dynactin subunit 5 (20 kDa, Protein from Sus scrofa)
- Hook3 (18 kDa, Protein from Homo sapiens)
- Dynactin subunit 2 (3 kDa, Protein from Sus scrofa)
- Complex of two dynein tail domains bound to dynactin and hook3 (Complex)
- Capping protein (actin filament) muscle z-line, alpha 1 (33 kDa, Protein from Sus scrofa)
- Dynactin subunit 1 (4 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (10 kDa, Protein from Sus scrofa)
- Actin related protein 10 homolog (43 kDa, Protein from Sus scrofa)