Cytoplasmic dynein (A1) bound to BICDR1
Resolution: 4.37 Å
EM Method: Single-particle
Fitted PDBs: 7z8k
Q-score: 0.29
Nature (2022) 610 pp. 212-216 [ Pubmed: 36071160 DOI: doi:10.1038/s41586-022-05186-y ]
- Bicdr1 (130 kDa, Cellular component from Mus musculus)
- Cytoplasmic dynein 1 heavy chain 1 (533 kDa, Protein from Homo sapiens)
- Cytoplasmic dynein 1 light intermediate chain 2 (54 kDa, Protein from Homo sapiens)
- Cytoplasmic dynein 1 intermediate chain 2 (63 kDa, Protein from Homo sapiens)
- Complex of dynein, dynactin, and bicdr1 bound to microtubules (4 MDa, Complex)
- Dynein, cytoplasmic 1 (1 MDa, Cellular component from Homo sapiens)
- Arp1 actin related protein 1 homolog a (42 kDa, Protein from Sus scrofa)
- Bicd family-like cargo adapter 1 (65 kDa, Protein from Mus musculus)
- Dynactin (1 MDa, Cellular component from Sus scrofa)
The pointed end complex of dynactin bound to BICDR1
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6znm
Q-score: 0.34
Lau CK, O'Reilly FJ, Santhanam B, Lacey SE, Rappsilber J, Carter AP
EMBO J (2021) 40 pp. e106164-e106164 [ Pubmed: 33734450 DOI: doi:10.15252/embj.2020106164 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Bicdr1 (Complex from Mus musculus)
- Actin, cytoplasmic 1 (41 kDa, Protein from Sus scrofa)
- Arp11 (46 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (44 kDa, Protein from Sus scrofa)
- Dynactin subunit 4 (52 kDa, Protein from Sus scrofa)
- Dynactin 6 (20 kDa, Protein from Sus scrofa)
- Dynactin (Complex from Sus scrofa)
- Bicd family-like cargo adapter 1,bicd family-like cargo adapter 1,bicdr1 (58 kDa, Protein from Mus musculus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Dynein-dynactin-bicdr1 complex (1 MDa, Complex)
- Arp1 actin related protein 1 homolog a (42 kDa, Protein from Sus scrofa)
- Dynactin subunit 5 (20 kDa, Protein from Sus scrofa)
The pointed end complex of dynactin bound to Hook3
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6znn
Q-score: 0.264
Lau CK, O'Reilly FJ, Santhanam B, Lacey SE, Rappsilber J, Carter AP
EMBO J (2021) 40 pp. e106164-e106164 [ Pubmed: 33734450 DOI: doi:10.15252/embj.2020106164 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Hook3 (7 kDa, Protein from Homo sapiens)
- Hook3 (Complex from Homo sapiens)
- Actin, cytoplasmic 1 (41 kDa, Protein from Sus scrofa)
- Arp11 (46 kDa, Protein from Sus scrofa)
- Dynactin subunit 2 (44 kDa, Protein from Sus scrofa)
- Dynactin subunit 4 (52 kDa, Protein from Sus scrofa)
- Putative hook3 coiled coil (5 kDa, Protein from Homo sapiens)
- Dynactin 6 (20 kDa, Protein from Sus scrofa)
- Hook3 (7 kDa, Protein from Homo sapiens)
- Dynactin (Complex from Sus scrofa)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Dynein-dynactin-hook3 complex (Complex)
- Arp1 actin related protein 1 homolog a (42 kDa, Protein from Sus scrofa)
- Dynactin subunit 5 (20 kDa, Protein from Sus scrofa)
CryoEM structure of dynactin complex at 4.1 angstrom resolution
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5adx
Q-score: 0.301
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
Science (2015) 347 pp. 1441-1446 [ DOI: doi:10.1126/science.aaa4080 Pubmed: 25814576 ]
- Actin related protein 1 (42 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 6 (27 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 4 (62 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 3 (22 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 2 (50 kDa, Protein from Sus scrofa domesticus)
- Actin related protein 11 (46 kDa, Protein from Sus scrofa domesticus)
- Dynactin complex from pig brain (1 MDa, Sample)
- Beta-actin (43 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 1 (150 kDa, Protein from Sus scrofa domesticus)
- Actin capping protein (33 kDa, Protein from Sus scrofa domesticus)
- Dynactin subunit 5 (25 kDa, Protein from Sus scrofa domesticus)